NZ245244A - Preparation of tigogenin-; 11-ketotigogenin-, hecogenin-, and diosgenin-beta-0-cellobioside heptaalkanoate from the relevant steroid in the presence of zinc fluoride or cyanide - Google Patents
Preparation of tigogenin-; 11-ketotigogenin-, hecogenin-, and diosgenin-beta-0-cellobioside heptaalkanoate from the relevant steroid in the presence of zinc fluoride or cyanideInfo
- Publication number
- NZ245244A NZ245244A NZ245244A NZ24524492A NZ245244A NZ 245244 A NZ245244 A NZ 245244A NZ 245244 A NZ245244 A NZ 245244A NZ 24524492 A NZ24524492 A NZ 24524492A NZ 245244 A NZ245244 A NZ 245244A
- Authority
- NZ
- New Zealand
- Prior art keywords
- tigogenin
- cellobioside
- zinc
- recited
- hecogenin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US79757491A | 1991-11-25 | 1991-11-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
NZ245244A true NZ245244A (en) | 1995-04-27 |
Family
ID=25171219
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NZ245244A NZ245244A (en) | 1991-11-25 | 1992-11-24 | Preparation of tigogenin-; 11-ketotigogenin-, hecogenin-, and diosgenin-beta-0-cellobioside heptaalkanoate from the relevant steroid in the presence of zinc fluoride or cyanide |
Country Status (13)
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2578399B2 (ja) * | 1992-06-26 | 1997-02-05 | ファイザー インク. | ステロイド−β−O−セロビオシドヘプタアルカノエートの製造方法 |
DK0647235T3 (da) * | 1992-06-26 | 1997-10-27 | Pfizer | Fremgangsmåde til steroide peracylglycosider |
EP0647234A1 (en) * | 1992-06-26 | 1995-04-12 | Pfizer Inc. | Steroidal glycosides for treating hypercholesterolemia |
CN1121722A (zh) * | 1993-04-28 | 1996-05-01 | 美国辉瑞有限公司 | 螺甾烷基苷结晶-水合物 |
US5502038A (en) * | 1993-06-21 | 1996-03-26 | Medical Research Foundation Of Oregon | Cholesterol sequestrant glycosides that inhibit intestinal cholesterol absorption |
EP0737202A1 (en) * | 1993-12-28 | 1996-10-16 | Pfizer Inc. | Hypocholesterolemic agents |
US6150336A (en) * | 1995-05-29 | 2000-11-21 | Pfizer Inc. | Steroidal glycosides |
US5756470A (en) * | 1996-10-29 | 1998-05-26 | Schering Corporation | Sugar-substituted 2-azetidinones useful as hypocholesterolemic agents |
US6982251B2 (en) | 2000-12-20 | 2006-01-03 | Schering Corporation | Substituted 2-azetidinones useful as hypocholesterolemic agents |
US7071181B2 (en) | 2001-01-26 | 2006-07-04 | Schering Corporation | Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors |
CN100509058C (zh) | 2001-01-26 | 2009-07-08 | 先灵公司 | 过氧化物酶体增殖物激活受体(ppar)活化剂和甾醇吸收抑制剂的组合药以及对于血管适应症的治疗 |
RS50406B (sr) | 2001-01-26 | 2009-12-31 | Schering Corporation, | Upotreba supstituisanih jedinjenja azetidinona za lečenje sitosterolemije |
ATE345793T1 (de) | 2001-09-21 | 2006-12-15 | Schering Corp | Behandlung von xanthom mittels azetidinon- derivate als hemmer der sterol absorption |
US7056906B2 (en) | 2001-09-21 | 2006-06-06 | Schering Corporation | Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women |
US7053080B2 (en) | 2001-09-21 | 2006-05-30 | Schering Corporation | Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors |
JP2006508188A (ja) | 2002-11-06 | 2006-03-09 | シェーリング コーポレイション | 脱髄の処置のためのコレステロール吸収インヒビター |
WO2004081003A1 (en) | 2003-03-07 | 2004-09-23 | Schering Corporation | Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholeterolemia |
US7459442B2 (en) | 2003-03-07 | 2008-12-02 | Schering Corporation | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof |
MXPA05009502A (es) | 2003-03-07 | 2005-10-18 | Schering Corp | Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia. |
MXPA05009503A (es) | 2003-03-07 | 2005-10-18 | Schering Corp | Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia. |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4602003A (en) * | 1982-05-17 | 1986-07-22 | Medical Research Foundation Of Oregon | Synthetic compounds to inhibit intestinal absorption of cholesterol in the treatment of hypercholesterolemia |
US4602005A (en) * | 1982-05-17 | 1986-07-22 | Medical Research Foundation Of Oregon | Tigogenin cellobioside for treating hypercholesterolemia and atherosclerosis |
-
1992
- 1992-10-15 CA CA002123684A patent/CA2123684A1/en not_active Abandoned
- 1992-10-15 AU AU27758/92A patent/AU659506B2/en not_active Ceased
- 1992-10-15 WO PCT/US1992/008638 patent/WO1993011150A1/en not_active Application Discontinuation
- 1992-10-15 JP JP5510090A patent/JPH0826064B2/ja not_active Expired - Lifetime
- 1992-10-15 EP EP92921860A patent/EP0619822A1/en not_active Withdrawn
- 1992-10-15 FI FI942394A patent/FI942394L/fi not_active Application Discontinuation
- 1992-10-15 HU HU9401374A patent/HUT67035A/hu unknown
- 1992-10-20 TW TW081108325A patent/TW232699B/zh active
- 1992-11-19 IL IL103797A patent/IL103797A0/xx unknown
- 1992-11-23 PT PT101088A patent/PT101088A/pt not_active Application Discontinuation
- 1992-11-24 NZ NZ245244A patent/NZ245244A/en unknown
- 1992-11-24 ZA ZA929081A patent/ZA929081B/xx unknown
- 1992-11-24 MX MX9206761A patent/MX9206761A/es not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU2775892A (en) | 1993-06-28 |
FI942394A7 (fi) | 1994-05-24 |
TW232699B (enrdf_load_html_response) | 1994-10-21 |
JPH06510794A (ja) | 1994-12-01 |
AU659506B2 (en) | 1995-05-18 |
WO1993011150A1 (en) | 1993-06-10 |
FI942394A0 (fi) | 1994-05-24 |
PT101088A (pt) | 1994-02-28 |
EP0619822A1 (en) | 1994-10-19 |
IL103797A0 (en) | 1993-04-04 |
ZA929081B (en) | 1994-05-24 |
HUT67035A (en) | 1995-01-30 |
MX9206761A (es) | 1995-01-31 |
HU9401374D0 (en) | 1994-08-29 |
FI942394L (fi) | 1994-05-24 |
JPH0826064B2 (ja) | 1996-03-13 |
CA2123684A1 (en) | 1993-06-10 |
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