NZ245244A - Preparation of tigogenin-; 11-ketotigogenin-, hecogenin-, and diosgenin-beta-0-cellobioside heptaalkanoate from the relevant steroid in the presence of zinc fluoride or cyanide - Google Patents

Preparation of tigogenin-; 11-ketotigogenin-, hecogenin-, and diosgenin-beta-0-cellobioside heptaalkanoate from the relevant steroid in the presence of zinc fluoride or cyanide

Info

Publication number
NZ245244A
NZ245244A NZ245244A NZ24524492A NZ245244A NZ 245244 A NZ245244 A NZ 245244A NZ 245244 A NZ245244 A NZ 245244A NZ 24524492 A NZ24524492 A NZ 24524492A NZ 245244 A NZ245244 A NZ 245244A
Authority
NZ
New Zealand
Prior art keywords
tigogenin
cellobioside
zinc
recited
hecogenin
Prior art date
Application number
NZ245244A
Other languages
English (en)
Inventor
Douglas J M Allen
Frank R Busch
John F Lambert
Russell J Shine
Stanley W Walinsky
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NZ245244A publication Critical patent/NZ245244A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NZ245244A 1991-11-25 1992-11-24 Preparation of tigogenin-; 11-ketotigogenin-, hecogenin-, and diosgenin-beta-0-cellobioside heptaalkanoate from the relevant steroid in the presence of zinc fluoride or cyanide NZ245244A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79757491A 1991-11-25 1991-11-25

Publications (1)

Publication Number Publication Date
NZ245244A true NZ245244A (en) 1995-04-27

Family

ID=25171219

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ245244A NZ245244A (en) 1991-11-25 1992-11-24 Preparation of tigogenin-; 11-ketotigogenin-, hecogenin-, and diosgenin-beta-0-cellobioside heptaalkanoate from the relevant steroid in the presence of zinc fluoride or cyanide

Country Status (13)

Country Link
EP (1) EP0619822A1 (enrdf_load_html_response)
JP (1) JPH0826064B2 (enrdf_load_html_response)
AU (1) AU659506B2 (enrdf_load_html_response)
CA (1) CA2123684A1 (enrdf_load_html_response)
FI (1) FI942394L (enrdf_load_html_response)
HU (1) HUT67035A (enrdf_load_html_response)
IL (1) IL103797A0 (enrdf_load_html_response)
MX (1) MX9206761A (enrdf_load_html_response)
NZ (1) NZ245244A (enrdf_load_html_response)
PT (1) PT101088A (enrdf_load_html_response)
TW (1) TW232699B (enrdf_load_html_response)
WO (1) WO1993011150A1 (enrdf_load_html_response)
ZA (1) ZA929081B (enrdf_load_html_response)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2578399B2 (ja) * 1992-06-26 1997-02-05 ファイザー インク. ステロイド−β−O−セロビオシドヘプタアルカノエートの製造方法
DK0647235T3 (da) * 1992-06-26 1997-10-27 Pfizer Fremgangsmåde til steroide peracylglycosider
EP0647234A1 (en) * 1992-06-26 1995-04-12 Pfizer Inc. Steroidal glycosides for treating hypercholesterolemia
CN1121722A (zh) * 1993-04-28 1996-05-01 美国辉瑞有限公司 螺甾烷基苷结晶-水合物
US5502038A (en) * 1993-06-21 1996-03-26 Medical Research Foundation Of Oregon Cholesterol sequestrant glycosides that inhibit intestinal cholesterol absorption
EP0737202A1 (en) * 1993-12-28 1996-10-16 Pfizer Inc. Hypocholesterolemic agents
US6150336A (en) * 1995-05-29 2000-11-21 Pfizer Inc. Steroidal glycosides
US5756470A (en) * 1996-10-29 1998-05-26 Schering Corporation Sugar-substituted 2-azetidinones useful as hypocholesterolemic agents
US6982251B2 (en) 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
US7071181B2 (en) 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
CN100509058C (zh) 2001-01-26 2009-07-08 先灵公司 过氧化物酶体增殖物激活受体(ppar)活化剂和甾醇吸收抑制剂的组合药以及对于血管适应症的治疗
RS50406B (sr) 2001-01-26 2009-12-31 Schering Corporation, Upotreba supstituisanih jedinjenja azetidinona za lečenje sitosterolemije
ATE345793T1 (de) 2001-09-21 2006-12-15 Schering Corp Behandlung von xanthom mittels azetidinon- derivate als hemmer der sterol absorption
US7056906B2 (en) 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
US7053080B2 (en) 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
JP2006508188A (ja) 2002-11-06 2006-03-09 シェーリング コーポレイション 脱髄の処置のためのコレステロール吸収インヒビター
WO2004081003A1 (en) 2003-03-07 2004-09-23 Schering Corporation Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholeterolemia
US7459442B2 (en) 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
MXPA05009502A (es) 2003-03-07 2005-10-18 Schering Corp Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia.
MXPA05009503A (es) 2003-03-07 2005-10-18 Schering Corp Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4602003A (en) * 1982-05-17 1986-07-22 Medical Research Foundation Of Oregon Synthetic compounds to inhibit intestinal absorption of cholesterol in the treatment of hypercholesterolemia
US4602005A (en) * 1982-05-17 1986-07-22 Medical Research Foundation Of Oregon Tigogenin cellobioside for treating hypercholesterolemia and atherosclerosis

Also Published As

Publication number Publication date
AU2775892A (en) 1993-06-28
FI942394A7 (fi) 1994-05-24
TW232699B (enrdf_load_html_response) 1994-10-21
JPH06510794A (ja) 1994-12-01
AU659506B2 (en) 1995-05-18
WO1993011150A1 (en) 1993-06-10
FI942394A0 (fi) 1994-05-24
PT101088A (pt) 1994-02-28
EP0619822A1 (en) 1994-10-19
IL103797A0 (en) 1993-04-04
ZA929081B (en) 1994-05-24
HUT67035A (en) 1995-01-30
MX9206761A (es) 1995-01-31
HU9401374D0 (en) 1994-08-29
FI942394L (fi) 1994-05-24
JPH0826064B2 (ja) 1996-03-13
CA2123684A1 (en) 1993-06-10

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