NZ244816A - Lyophilised pharmaceutical compositions of ifosfamide and urea - Google Patents

Lyophilised pharmaceutical compositions of ifosfamide and urea

Info

Publication number
NZ244816A
NZ244816A NZ244816A NZ24481692A NZ244816A NZ 244816 A NZ244816 A NZ 244816A NZ 244816 A NZ244816 A NZ 244816A NZ 24481692 A NZ24481692 A NZ 24481692A NZ 244816 A NZ244816 A NZ 244816A
Authority
NZ
New Zealand
Prior art keywords
ifosfamide
urea
lyophilizate
weight
compositions
Prior art date
Application number
NZ244816A
Other languages
English (en)
Inventor
Robert Lee Alexander
Robert Joseph Behme
Joseph Arthur Scott
Dana Brooke
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of NZ244816A publication Critical patent/NZ244816A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/665Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Materials For Medical Uses (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Cosmetics (AREA)
NZ244816A 1991-10-23 1992-10-20 Lyophilised pharmaceutical compositions of ifosfamide and urea NZ244816A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/781,436 US5227373A (en) 1991-10-23 1991-10-23 Lyophilized ifosfamide compositions

Publications (1)

Publication Number Publication Date
NZ244816A true NZ244816A (en) 1994-06-27

Family

ID=25122737

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ244816A NZ244816A (en) 1991-10-23 1992-10-20 Lyophilised pharmaceutical compositions of ifosfamide and urea

Country Status (24)

Country Link
US (1) US5227373A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0538858B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP3576180B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR100247161B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN1046202C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE175354T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU658011B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2081061A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CZ (1) CZ282445B6 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE69228105T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK0538858T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EG (1) EG20114A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2125880T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI107701B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR3029835T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (2) HU221428B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL103496A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MX (1) MX9206105A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MY (1) MY109794A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ244816A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RU (1) RU2106138C1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SK (1) SK279869B6 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TW217987B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA928104B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (33)

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WO1995007083A1 (en) * 1993-09-10 1995-03-16 F.H. Faulding & Co. Limited Ifosfamide lyophilisate composition
US5789000A (en) * 1994-11-14 1998-08-04 Bionumerik Pharmaceuticals, Inc. Sterile aqueous parenteral formulations of cis-diammine dichloro platinum
DE19529057B4 (de) * 1995-08-08 2007-12-13 Baxter Healthcare S.A. Ifosfamid-Lyophilisat-Zubereitungen
KR100246757B1 (ko) 1997-05-09 2000-03-15 윤종용 트랜스컨덕턴스 가변방법 및 회로와 그를 이용한 가변 대역 필터 및 가변 이득 증폭기
DE19733305A1 (de) * 1997-08-01 1999-02-04 Asta Medica Ag Pharmazeutische Zusammensetzung enthaltend Ifosfamid und Carnitin
AU1555099A (en) * 1997-10-13 1999-05-03 Stada Arzneimittel A.G. Liquid presentations of oxazaphosphorine-containing pharmaceutical products
US5972912A (en) * 1998-12-17 1999-10-26 S.P. Pharmaceuticals Method for lyophilizing ifosfamide
CN1126547C (zh) * 2000-07-19 2003-11-05 南京振中生物工程有限公司 香菇多糖冻干粉针剂及其制备方法
US6613927B1 (en) 2002-02-08 2003-09-02 American Pharmaceutical Partners, Inc. Sterile lyophilized ifosfamide and associated methods
PL205936B1 (pl) 2002-02-22 2010-06-30 Schering Corp Farmaceutyczny preparat zawierający termozolomid oraz sposób jego wytwarzania
KR101037313B1 (ko) * 2002-09-05 2011-05-26 바라트 쎄럼스 앤드 백신스 리미티드 메스나를 함유하는 안정한 액체 옥스아자포스포린 조성물
DE60332385D1 (de) * 2002-12-02 2010-06-10 Bharat Serums & Vaccines Ltd Ifosfamid-zusammensetzungen zur parenteralen verabreichung und verfahren für ihre herstellung
US7199111B2 (en) * 2002-12-02 2007-04-03 Bharat Serums & Vaccines Ltd. Aqueous ifosfamide compositions for parenteral administration and a process for their preparations
DK1667655T3 (da) * 2003-10-01 2011-10-24 Baxter Int Ny anvendelse, farmaceutiske præparater og en fremgangsmåde til deres fremstilling
AU2005317047A1 (en) * 2004-11-05 2006-06-22 Cephalon, Inc. Cancer treatments
US8436190B2 (en) 2005-01-14 2013-05-07 Cephalon, Inc. Bendamustine pharmaceutical compositions
EP1973406B1 (en) 2005-12-28 2014-03-12 Advanced Bionutrition Corporation A delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form
US8968721B2 (en) 2005-12-28 2015-03-03 Advanced Bionutrition Corporation Delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form and methods of making same
EP2071917B1 (en) * 2006-09-29 2012-11-21 Infa S.A. Packaging system for pharmaceutical compositions and kit for intravenous administration
WO2008076975A1 (en) 2006-12-18 2008-06-26 Advanced Bionutrition Corporation A dry food product containing live probiotic
AU2008251921A1 (en) * 2007-05-08 2008-11-20 Merck Sharp & Dohme Corp. Methods of treatment using intravenous formulations comprising temozolomide
AR072777A1 (es) 2008-03-26 2010-09-22 Cephalon Inc Formas solidas de clorhidrato de bendamustina
EP2326306A1 (en) 2008-09-25 2011-06-01 Cephalon, Inc. Liquid formulations of bendamustine
US8076366B2 (en) * 2009-01-15 2011-12-13 Cephalon, Inc. Forms of bendamustine free base
CA2986751A1 (en) 2009-03-27 2010-09-30 Intervet International B.V. Microparticulated vaccines for the oral or nasal vaccination and boostering of animals including fish
DK2435554T3 (en) * 2009-05-26 2017-10-30 Advanced Bionutrition Corp STABLE DRY POWDER COMPOSITION WITH BIOLOGICALLY ACTIVE MICRO-ORGANISMS AND / OR BIOACTIVE MATERIALS AND PROCEDURES FOR ITS PREPARATION
US9504750B2 (en) 2010-01-28 2016-11-29 Advanced Bionutrition Corporation Stabilizing composition for biological materials
WO2011094469A2 (en) 2010-01-28 2011-08-04 Advanced Bionutrition Corporation Dry glassy composition comprising a bioactive material
JP5727611B2 (ja) 2010-08-13 2015-06-03 アドバンスド バイオニュートリション コーポレイション 生体物質用の乾燥貯蔵安定化組成物
ES2750749T3 (es) 2014-01-06 2020-03-27 Auxin Surgery Sa Composiciones de Mesna liofilizadas
US10342769B2 (en) 2014-11-14 2019-07-09 Navinta Iii Inc Carmustine pharmaceutical composition
ES2881809T3 (es) 2015-07-29 2021-11-30 Advanced Bionutrition Corp Composiciones probióticas secas estables para usos dietéticos especiales
JP6706988B2 (ja) * 2016-07-20 2020-06-10 日本化薬株式会社 ボルテゾミブを含有する医薬組成物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3732340A (en) * 1966-07-11 1973-05-08 Asta Werke Ag Chem Fab N',o-propylene phosphoric acid ester diamides
US4537883A (en) * 1982-11-12 1985-08-27 Mead Johnson & Company Lyophilized cyclophosphamide
ZA851062B (en) * 1984-03-01 1985-11-27 Asta Werke Ag Chem Fab Salts of oxazaphosphorine derivatives and process for their production
DE3722043A1 (de) * 1986-07-11 1988-01-14 Asta Werke Ag Chem Fab Loesungen von oxazaphosphorinen mit verbesserter stabilitaet und verfahren zu deren herstellung
NO873860L (no) * 1986-10-31 1988-05-02 Asta Pharma Ag Ifosfamid-lyofilisat og fremgangsmaate til deres fremstilling.
ES2021771B3 (es) * 1987-03-06 1991-11-16 Asta Pharma Ag Procedimiento para la obtencion de ifosfamida con propiedades mejoradas.
EP0334083B1 (de) * 1988-03-19 1991-07-24 ASTA Pharma Aktiengesellschaft Ifosfamid-Mesna-Lyophilisat und Verfahren zu dessen Herstellung
US5036060A (en) * 1988-07-25 1991-07-30 Fujisawa Usa, Inc. Cyclophosphamide

Also Published As

Publication number Publication date
US5227373A (en) 1993-07-13
ATE175354T1 (de) 1999-01-15
IL103496A0 (en) 1993-03-15
SK317692A3 (en) 1995-11-08
RU2106138C1 (ru) 1998-03-10
DE69228105T2 (de) 1999-08-26
HU211293A9 (en) 1995-11-28
DE69228105D1 (de) 1999-02-18
FI924797A0 (fi) 1992-10-22
MY109794A (en) 1997-06-30
TW217987B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-12-21
CZ282445B6 (cs) 1997-07-16
EP0538858A1 (en) 1993-04-28
SK279869B6 (sk) 1999-04-13
JP3576180B2 (ja) 2004-10-13
FI107701B (fi) 2001-09-28
CZ317692A3 (en) 1993-09-15
CN1046202C (zh) 1999-11-10
IL103496A (en) 1996-07-23
CN1073358A (zh) 1993-06-23
HU221428B (en) 2002-10-28
CA2081061A1 (en) 1993-04-24
DK0538858T3 (da) 1999-08-30
AU658011B2 (en) 1995-03-30
FI924797L (fi) 1993-04-24
ES2125880T3 (es) 1999-03-16
JPH05246856A (ja) 1993-09-24
KR930007453A (ko) 1993-05-20
ZA928104B (en) 1993-07-20
GR3029835T3 (en) 1999-06-30
EG20114A (en) 1997-07-31
HUT69384A (en) 1995-09-28
HU9203306D0 (en) 1992-12-28
EP0538858B1 (en) 1999-01-07
AU2716692A (en) 1993-04-29
KR100247161B1 (ko) 2000-04-01
MX9206105A (es) 1993-04-01

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