NZ244371A - Pyridyl-substituted benzylsulphides and analogues and pharmaceutical compositions - Google Patents

Pyridyl-substituted benzylsulphides and analogues and pharmaceutical compositions

Info

Publication number
NZ244371A
NZ244371A NZ244371A NZ24437192A NZ244371A NZ 244371 A NZ244371 A NZ 244371A NZ 244371 A NZ244371 A NZ 244371A NZ 24437192 A NZ24437192 A NZ 24437192A NZ 244371 A NZ244371 A NZ 244371A
Authority
NZ
New Zealand
Prior art keywords
pyridyl
methoxyphenyl
carboxyethenyl
phenyl
octyloxy
Prior art date
Application number
NZ244371A
Other languages
English (en)
Inventor
Pamela Anne Chambers
Robert A Daines
Dalia R Jakas
William D Kingsbury
Israil Pendrak
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of NZ244371A publication Critical patent/NZ244371A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/65One oxygen atom attached in position 3 or 5

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
NZ244371A 1991-09-19 1992-09-17 Pyridyl-substituted benzylsulphides and analogues and pharmaceutical compositions NZ244371A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US76271091A 1991-09-19 1991-09-19
US79093191A 1991-11-12 1991-11-12
US80959391A 1991-12-18 1991-12-18
US93286992A 1992-08-20 1992-08-20
CN93103596A CN1092409A (zh) 1991-09-19 1993-03-19 用于治疗白三烯有关的疾病的化合物

Publications (1)

Publication Number Publication Date
NZ244371A true NZ244371A (en) 1995-11-27

Family

ID=36809157

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ244371A NZ244371A (en) 1991-09-19 1992-09-17 Pyridyl-substituted benzylsulphides and analogues and pharmaceutical compositions

Country Status (12)

Country Link
EP (1) EP0604529A1 (zh)
JP (1) JPH06510786A (zh)
CN (1) CN1092409A (zh)
AP (1) AP333A (zh)
AU (1) AU2573592A (zh)
CA (1) CA2119467A1 (zh)
IL (1) IL103205A0 (zh)
MA (1) MA22649A1 (zh)
MX (1) MX9205358A (zh)
NZ (1) NZ244371A (zh)
PT (1) PT100881A (zh)
WO (1) WO1993006085A1 (zh)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3181917B2 (ja) * 1992-06-30 2001-07-03 スミスクライン・ビーチャム・コーポレイション フェニルチオメチルピリジニルアルケノアート類の製造方法
GB9313145D0 (en) * 1993-06-25 1993-08-11 Smithkline Beecham Plc Process
IL115420A0 (en) 1994-09-26 1995-12-31 Zeneca Ltd Aminoheterocyclic derivatives
EP0812194B1 (en) * 1995-03-02 2000-08-16 Smithkline Beecham Corporation Use of substituted pyridine compounds for treating atopic dermatitis and contact dermatitis
GB9508137D0 (en) * 1995-04-21 1995-06-07 Smithkline Beecham Plc Formulation
JP2000504336A (ja) 1996-02-02 2000-04-11 ゼネカ・リミテッド 薬学製剤として有用なヘテロ環式化合物
GB9602166D0 (en) 1996-02-02 1996-04-03 Zeneca Ltd Aminoheterocyclic derivatives
US5929096A (en) * 1996-02-29 1999-07-27 Smithkline Beecham Corporation Method for treating atopic dermatitis and contact dermatitis
KR20000029984A (ko) * 1996-08-14 2000-05-25 사라 엔 람베쓰 치환된피리미딘유도체및이의약학적용도
AU4557397A (en) * 1996-09-26 1998-04-17 Novartis Ag Aryl-substituted acrylamides with leukotriene b4 (ltb-4) receptor antagonist activity
UA56197C2 (uk) 1996-11-08 2003-05-15 Зенека Лімітед Гетероциклічні похідні
US6440972B1 (en) 1997-02-13 2002-08-27 Zeneca Limited Heterocyclic compounds useful as oxido-squalene cyclase inhibitors
DE69815509T2 (de) 1997-02-13 2004-05-13 Astrazeneca Ab Heterozyklische verbindungen die als oxido-squalen-zyklase-inhibitoren anwendung finden
GB9715895D0 (en) 1997-07-29 1997-10-01 Zeneca Ltd Heterocyclic compounds
GB9902989D0 (en) 1999-02-11 1999-03-31 Zeneca Ltd Heterocyclic derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4056619A (en) * 1975-09-08 1977-11-01 Warner-Lambert Company 1-Substituted-2-(2-pyridinyl)ethanone N-oxides
CA1322004C (en) * 1987-11-25 1993-09-07 Merck Frosst Canada Incorporated Pyridyl styrene dialkanoic acids
HUT64747A (en) * 1990-06-07 1994-02-28 Smithkline Beecham Corp Process for producing benzoic acid derivatives and pharmaceutical preparatives containing them

Also Published As

Publication number Publication date
AP333A (en) 1994-04-25
AU2573592A (en) 1993-04-27
JPH06510786A (ja) 1994-12-01
PT100881A (pt) 1993-10-29
AP9200428A0 (en) 1992-10-31
IL103205A0 (en) 1993-02-21
MA22649A1 (fr) 1993-04-01
WO1993006085A1 (en) 1993-04-01
CA2119467A1 (en) 1993-04-01
MX9205358A (es) 1993-07-01
CN1092409A (zh) 1994-09-21
EP0604529A1 (en) 1994-07-06

Similar Documents

Publication Publication Date Title
AP333A (en) Phenyl-substituted pyridyl aliphatic compounds for treating leukotriene-related diseases.
AU655428B2 (en) Benzoic acid derivatives
AU707102B2 (en) Pharmaceutical pyridine compounds
US5643914A (en) Pharmaceutical pyridine compounds
IE911912A1 (en) Pyridyl-benzoic acid derivatives for treating¹leukotriene-related diseases
US5656636A (en) Pyridine compounds for treating leukotriene-related diseases
WO1991018883A1 (en) Amide linked pyridyle-benzoic acid derivatives for treating leukotriene-related diseases
WO1991018879A1 (en) Phthalamic acids and their isomers for treating leukotriene-related diseases
EP0639975A1 (en) Heterocyclic-substituted pyridine compounds and uses
WO1995015950A1 (en) Compounds
WO1993011768A1 (en) Pyridyl compounds for psoriasis treatment
WO1993022285A1 (en) Leukotriene antagonists
EP0732919A1 (en) Diphenyl-2-propenoates and homologs thereof useful for treating diseases associated with leukotriene b4
SI9200314A (sl) Spojine za zdravuanje bolezni, ki so v zvezi z levkotrieni