NZ222939A - Human interleukin-3, production using genetic engineering methods, antibodies to human interleukin-3 and screening of dna library with 3' untranslated region - Google Patents

Human interleukin-3, production using genetic engineering methods, antibodies to human interleukin-3 and screening of dna library with 3' untranslated region

Info

Publication number
NZ222939A
NZ222939A NZ222939A NZ22293987A NZ222939A NZ 222939 A NZ222939 A NZ 222939A NZ 222939 A NZ222939 A NZ 222939A NZ 22293987 A NZ22293987 A NZ 22293987A NZ 222939 A NZ222939 A NZ 222939A
Authority
NZ
New Zealand
Prior art keywords
human
dna
protein
pgb
sequence
Prior art date
Application number
NZ222939A
Other languages
English (en)
Inventor
Lambertus Christiaan Dorssers
Gerard Wagemaker
Yvonne Johanna Vos
Leen Robert Willem Van
Original Assignee
Gist Brocades Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades Nv filed Critical Gist Brocades Nv
Publication of NZ222939A publication Critical patent/NZ222939A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/5403IL-3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NZ222939A 1986-12-16 1987-12-16 Human interleukin-3, production using genetic engineering methods, antibodies to human interleukin-3 and screening of dna library with 3' untranslated region NZ222939A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP86202285 1986-12-16
EP87201322 1987-07-13

Publications (1)

Publication Number Publication Date
NZ222939A true NZ222939A (en) 1991-03-26

Family

ID=26103432

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ222939A NZ222939A (en) 1986-12-16 1987-12-16 Human interleukin-3, production using genetic engineering methods, antibodies to human interleukin-3 and screening of dna library with 3' untranslated region

Country Status (14)

Country Link
JP (2) JPH01502157A (ja)
AT (1) ATE161882T1 (ja)
AU (1) AU617095B2 (ja)
CA (1) CA1341503C (ja)
DE (1) DE3752158T2 (ja)
ES (1) ES2113338T3 (ja)
FI (1) FI102293B (ja)
GR (1) GR3025857T3 (ja)
IE (1) IE81129B1 (ja)
IL (1) IL84852A (ja)
NO (1) NO180544C (ja)
NZ (1) NZ222939A (ja)
PT (1) PT86381B (ja)
WO (1) WO1988004691A1 (ja)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR871029B (en) * 1986-07-14 1987-11-02 Genetics Inst Novel osteoinductive factors
US6238889B1 (en) 1986-12-16 2001-05-29 Dsm N.V. Molecular cloning and expression of the Pro8 isoform of human IL-3
OA09736A (en) * 1987-02-18 1993-11-30 Schering Biotech Corp "Human interleukin-3 and muteins thereof".
US5304637A (en) * 1987-07-13 1994-04-19 Gist-Brocades N.V. Expression and purification of human interleukin-3 and muteins thereof
GB2210883B (en) * 1987-10-08 1992-01-02 British Bio Technology Synthetic interleukin-3 gene
US6384194B1 (en) 1987-12-16 2002-05-07 Dsm N.V. Expression and purification of human interleukin-3 and muteins thereof
EP0425536A4 (en) * 1988-07-20 1992-01-02 Immunex Corporation Nonglycosylated human interleukin-3 compositions
NZ232913A (en) * 1989-03-15 1992-08-26 Gist Brocades Nv Il-3 produced recombinantly and purified to homogeneity; vectors and pharmaceutical preparations
US5128450A (en) * 1989-06-30 1992-07-07 Urdal David L Nonglycosylated human interleukin-3 analog proteins
US5516512A (en) 1989-08-14 1996-05-14 Gist-Brocades, N.V. N- and C-terminal truncation and deletion mutants of human interleukin-3
ES2106017T3 (es) 1989-08-14 1997-11-01 Gist Brocades Nv Mutantes de interleucina-3 humana.
DK0596881T3 (da) * 1991-08-01 1997-10-13 Fond Nat Transfusion Sanguine Ekspression i ikke-tumurale humane lymofoblastoider med en integrativ vektor
US5738849A (en) * 1992-11-24 1998-04-14 G. D. Searle & Co. Interleukin-3 (IL-3) variant fusion proteins, their recombinant production, and therapeutic compositions comprising them
WO1994012639A2 (en) * 1992-11-24 1994-06-09 G. D. Searle & Co. Interleukin-3 (il-3) mutant polypeptides
US5501962A (en) * 1993-06-21 1996-03-26 G. D. Searle & Co. Interleuken-3 (IL-3) human/murine hybrid polypeptides and recombinant production of the same
US6017523A (en) * 1995-06-06 2000-01-25 G.D. Searle & Co. Therapeutic methods employing mutant human interleukin-3 (IL-3) polypeptides
WO1999041382A2 (en) * 1998-02-17 1999-08-19 Hyseq, Inc. A novel interleukin-3 and uses thereof
JP2008527981A (ja) * 2005-01-25 2008-07-31 アポロ ライフ サイエンシズ リミテッド 治療目的および診断目的のためにパラメーターにより選択されたgm−csf、il−3、il−4、il−5、ならびにそのキメラ
WO2007123689A1 (en) * 2006-04-03 2007-11-01 New England Biolabs, Inc. Expression, secretion and purification of recombinant bovine serum albumin (rbsa) and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4695542A (en) * 1983-10-04 1987-09-22 Dnax Research Institute Of Molecular And Cellular Biology, Inc. cDNA clones coding for polypeptides exhibiting multi-lineage cellular growth factor activity
AU570762B2 (en) * 1983-12-23 1988-03-24 Australian National University, The Cloning of cdna for il-3
GR871029B (en) * 1986-07-14 1987-11-02 Genetics Inst Novel osteoinductive factors

Also Published As

Publication number Publication date
NO883614L (no) 1988-08-12
IE81129B1 (en) 2000-03-22
IL84852A0 (en) 1988-06-30
WO1988004691A1 (en) 1988-06-30
PT86381A (en) 1988-01-01
FI883688A (fi) 1988-08-08
DE3752158D1 (de) 1998-02-12
PT86381B (pt) 1990-11-20
ATE161882T1 (de) 1998-01-15
ES2113338T3 (es) 1998-05-01
GR3025857T3 (en) 1998-04-30
FI102293B1 (fi) 1998-11-13
FI102293B (fi) 1998-11-13
JPH1080286A (ja) 1998-03-31
AU1057788A (en) 1988-07-15
DE3752158T2 (de) 1998-05-20
NO180544B (no) 1997-01-27
NO883614D0 (no) 1988-08-12
AU617095B2 (en) 1991-11-21
JPH01502157A (ja) 1989-08-03
FI883688A0 (fi) 1988-08-08
CA1341503C (en) 2006-04-04
IL84852A (en) 1994-06-24
IE873409L (en) 1988-06-12
NO180544C (no) 1997-05-07

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