NZ207184A - Naphthyl and indenyl derivatives of imidazole and pyrimidine:pharmaceutical compositions - Google Patents

Naphthyl and indenyl derivatives of imidazole and pyrimidine:pharmaceutical compositions

Info

Publication number
NZ207184A
NZ207184A NZ207184A NZ20718484A NZ207184A NZ 207184 A NZ207184 A NZ 207184A NZ 207184 A NZ207184 A NZ 207184A NZ 20718484 A NZ20718484 A NZ 20718484A NZ 207184 A NZ207184 A NZ 207184A
Authority
NZ
New Zealand
Prior art keywords
methyl
dihydro
compound
imidazole
naphthalenyl
Prior art date
Application number
NZ207184A
Other languages
English (en)
Inventor
D M Bailey
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of NZ207184A publication Critical patent/NZ207184A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/58Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/18Monohydroxylic alcohols containing only six-membered aromatic rings as cyclic part
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/34Monohydroxylic alcohols containing six-membered aromatic rings and other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/06Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/22Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NZ207184A 1983-03-14 1984-02-16 Naphthyl and indenyl derivatives of imidazole and pyrimidine:pharmaceutical compositions NZ207184A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/475,193 US4540705A (en) 1983-03-14 1983-03-14 Antidepressant imidazolines and related compounds

Publications (1)

Publication Number Publication Date
NZ207184A true NZ207184A (en) 1986-12-05

Family

ID=23886585

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ207184A NZ207184A (en) 1983-03-14 1984-02-16 Naphthyl and indenyl derivatives of imidazole and pyrimidine:pharmaceutical compositions

Country Status (16)

Country Link
US (1) US4540705A (OSRAM)
EP (1) EP0125410A3 (OSRAM)
JP (1) JPS59193875A (OSRAM)
KR (1) KR900001216B1 (OSRAM)
AU (1) AU568839B2 (OSRAM)
CA (1) CA1215369A (OSRAM)
DK (1) DK112984A (OSRAM)
ES (1) ES8601907A1 (OSRAM)
FI (1) FI840839A7 (OSRAM)
GR (1) GR81813B (OSRAM)
IL (1) IL70966A (OSRAM)
NO (1) NO840893L (OSRAM)
NZ (1) NZ207184A (OSRAM)
PH (1) PH19715A (OSRAM)
PT (1) PT78195B (OSRAM)
ZA (1) ZA841323B (OSRAM)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9016800D0 (en) * 1990-07-31 1990-09-12 Shell Int Research Tetrahydropyrimidine derivatives
HUP0004037A3 (en) * 1997-10-02 2002-03-28 Daiichi Seiyaku Co Novel dihydronaphthalene compounds and process for producing the same
US6559157B2 (en) 1997-10-02 2003-05-06 Daiichi Pharmaceutical Co., Ltd. Dihydronaphthalene compounds
US6841684B2 (en) 1997-12-04 2005-01-11 Allergan, Inc. Imidiazoles having reduced side effects
US6329369B1 (en) 1997-12-04 2001-12-11 Allergan Sales, Inc. Methods of treating pain and other conditions
EP1266897A3 (en) * 1997-12-19 2003-12-03 Eli Lilly And Company Hypoglycemic imidazoline compounds
WO1999032112A1 (en) * 1997-12-19 1999-07-01 Eli Lilly And Company Method for treating diabetes
US6410562B1 (en) 1998-12-18 2002-06-25 Eli Lilly And Company Hypoglycemic imidazoline compounds
FR2787451B1 (fr) * 1998-12-18 2001-01-26 Adir Nouveaux composes imidazoliniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
BRPI0707315A2 (pt) * 2006-01-27 2011-05-03 Hoffmann La Roche uso de 2-imidazol substituìdo de derivados de imidazolina
ES2381589T3 (es) 2006-10-19 2012-05-29 F. Hoffmann-La Roche Ag Aminometil-4-imidazoles
BRPI0718054A2 (pt) 2006-11-02 2013-11-05 Hoffmann La Roche 2-imidazóis substituídos como moduladores de receptores associados à traços de aminas
EP2084152A2 (en) 2006-11-16 2009-08-05 F. Hoffmann-Roche AG Substituted 4-imidazoles
JP2010513238A (ja) 2006-12-13 2010-04-30 エフ.ホフマン−ラ ロシュ アーゲー 微量アミン関連受容体(taar)に対するリガンドとしての新規2−イミダゾール
US20080146523A1 (en) 2006-12-18 2008-06-19 Guido Galley Imidazole derivatives
US7582691B2 (en) * 2007-01-17 2009-09-01 Sabic Innovative Plastics Ip B.V. Poly(arylene ether) compositions and articles
KR101174191B1 (ko) 2007-02-02 2012-08-14 에프. 호프만-라 로슈 아게 중추 신경계 장애의 치료용 taar1 리간드로서 2-아미노옥사졸린
JP5130305B2 (ja) 2007-02-15 2013-01-30 エフ.ホフマン−ラ ロシュ アーゲー Taar1リガンドとしての2−アミノオキサゾリン
CA2691082A1 (en) 2007-07-02 2009-01-08 F. Hoffmann-La Roche Ag 2 -imidazolines having a good affinity to the trace amine associated receptors (taars)
JP2010531836A (ja) 2007-07-03 2010-09-30 エフ.ホフマン−ラ ロシュ アーゲー 4−イミダゾリン及びそれらの抗うつ剤としての使用
AU2008281918A1 (en) 2007-07-27 2009-02-05 F. Hoffmann-La Roche Ag 2-azetidinemethaneamines and 2-pyrrolidinemethaneamines as TAAR-ligands
CA2695331A1 (en) 2007-08-03 2009-02-12 F. Hoffmann-La Roche Ag Pyridinecarboxamide and benzamide derivatives as taar1 ligands
US8242153B2 (en) 2008-07-24 2012-08-14 Hoffmann-La Roche Inc. 4,5-dihydro-oxazol-2YL derivatives
US8354441B2 (en) 2009-11-11 2013-01-15 Hoffmann-La Roche Inc. Oxazoline derivatives
US9452980B2 (en) 2009-12-22 2016-09-27 Hoffmann-La Roche Inc. Substituted benzamides
JP6814814B2 (ja) 2016-03-17 2021-01-20 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft Taarのアゴニストとしての活性を有する5−エチル−4−メチル−ピラゾール−3−カルボキサミド誘導体

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2731471A (en) * 1956-01-17 Nxg hi
US2161938A (en) * 1934-07-31 1939-06-13 Soc Of Chemical Ind Imidazolines
FR926661A (fr) * 1941-07-09 1947-10-08 Lovens Kemiske Fabrik V Aug Ko Méthyle-imidazolines substituées et leur procédé de préparation
GB757650A (en) * 1953-06-15 1956-09-19 Pfizer & Co C Improvements in or relating to substituted imidazolines and the preparation thereof
DE1150180B (de) * 1962-04-12 1963-06-12 Merck Ag E Mittel zur Vorbehandlung der Haut fuer die Rasur
GB1317514A (en) * 1970-11-30 1973-05-23 Erba Carlo Spa Imidazoline derivatives
US4085209A (en) * 1975-02-05 1978-04-18 Rohm And Haas Company Preparation and safening effect of 1-substituted imidazole metal salt complexes

Also Published As

Publication number Publication date
NO840893L (no) 1984-09-17
KR840008327A (ko) 1984-12-14
AU2487784A (en) 1984-09-20
KR900001216B1 (ko) 1990-02-28
EP0125410A3 (en) 1987-01-14
ZA841323B (en) 1984-10-31
PT78195A (en) 1984-04-01
DK112984D0 (da) 1984-02-28
ES530345A0 (es) 1985-11-16
EP0125410A2 (en) 1984-11-21
US4540705A (en) 1985-09-10
FI840839A7 (fi) 1984-09-15
ES8601907A1 (es) 1985-11-16
IL70966A (en) 1987-08-31
FI840839A0 (fi) 1984-03-02
GR81813B (OSRAM) 1984-12-12
JPS59193875A (ja) 1984-11-02
PT78195B (en) 1986-04-24
AU568839B2 (en) 1988-01-14
IL70966A0 (en) 1984-05-31
DK112984A (da) 1984-09-15
PH19715A (en) 1986-06-17
CA1215369A (en) 1986-12-16

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