ATE264304T1 - Dihydronaphthalinderivate und verfahren zur herstellung derselben - Google Patents
Dihydronaphthalinderivate und verfahren zur herstellung derselbenInfo
- Publication number
- ATE264304T1 ATE264304T1 AT98945556T AT98945556T ATE264304T1 AT E264304 T1 ATE264304 T1 AT E264304T1 AT 98945556 T AT98945556 T AT 98945556T AT 98945556 T AT98945556 T AT 98945556T AT E264304 T1 ATE264304 T1 AT E264304T1
- Authority
- AT
- Austria
- Prior art keywords
- inhibiting activity
- cancer
- dihydronaphthaline
- derivatives
- producing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Endocrinology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP28426397 | 1997-10-02 | ||
| PCT/JP1998/004426 WO1999018075A1 (en) | 1997-10-02 | 1998-10-01 | Novel dihydronaphthalene compounds and process for producing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE264304T1 true ATE264304T1 (de) | 2004-04-15 |
Family
ID=17676271
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98945556T ATE264304T1 (de) | 1997-10-02 | 1998-10-01 | Dihydronaphthalinderivate und verfahren zur herstellung derselben |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP1028110B1 (de) |
| KR (1) | KR20000069426A (de) |
| CN (1) | CN1117732C (de) |
| AT (1) | ATE264304T1 (de) |
| AU (1) | AU743405B2 (de) |
| CA (1) | CA2298527A1 (de) |
| DE (1) | DE69823222T2 (de) |
| DK (1) | DK1028110T3 (de) |
| ES (1) | ES2218853T3 (de) |
| FI (1) | FI20000207A7 (de) |
| HU (1) | HUP0004037A3 (de) |
| IL (1) | IL133483A0 (de) |
| NO (1) | NO315044B1 (de) |
| NZ (1) | NZ501822A (de) |
| RU (1) | RU2203890C2 (de) |
| WO (1) | WO1999018075A1 (de) |
| ZA (1) | ZA988954B (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100287366B1 (ko) | 1997-11-24 | 2001-04-16 | 윤순조 | 엠피이지 방식을 이용한 휴대용 음향 재생장치 및 방법 |
| US7001926B2 (en) | 2000-03-10 | 2006-02-21 | Oxigene, Inc. | Tubulin binding agents and corresponding prodrug constructs |
| TWI283669B (en) * | 1999-06-10 | 2007-07-11 | Allergan Inc | Compounds and method of treatment having agonist-like activity selective at alpha 2B or 2B/2C adrenergic receptors |
| US6849656B1 (en) | 1999-09-17 | 2005-02-01 | Baylor University | Indole-containing and combretastatin-related anti-mitotic and anti-tubulin polymerization agents |
| JP4520012B2 (ja) * | 1999-10-22 | 2010-08-04 | 武田薬品工業株式会社 | １−置換−１−（１ｈ−イミダゾール−４−イル）メタノール類 |
| WO2001030764A1 (en) * | 1999-10-22 | 2001-05-03 | Takeda Chemical Industries, Ltd. | 1-substituted phenyl-1-(1h-imidazol-4-yl) alcohols, process for producing the same and use thereof |
| JP4616454B2 (ja) * | 1999-10-22 | 2011-01-19 | 武田薬品工業株式会社 | １−置換フェニル−１−（１ｈ−イミダゾール−４−イル）アルコール類、その製造法および用途 |
| US7091240B2 (en) | 2000-03-10 | 2006-08-15 | Oxigene, Inc. | Tubulin binding ligands and corresponding prodrug constructs |
| JP2004505888A (ja) | 2000-03-10 | 2004-02-26 | ベイラー・ユニバーシテイ | チューブリン結合リガンドおよび対応するプロドラッグ構造 |
| EP1334106B1 (de) | 2000-11-17 | 2006-05-24 | Takeda Pharmaceutical Company Limited | Imidazol derivate, ihre herstellung und ihre verwendung |
| ATE502030T1 (de) | 2000-11-20 | 2011-04-15 | Takeda Pharmaceutical | Imidazolderivate, verfahren zu deren herstellung und deren verwendung |
| WO2002046186A1 (en) | 2000-12-08 | 2002-06-13 | Takeda Chemical Industries, Ltd. | Substituted thiazole derivatives bearing 3-pyridyl groups, process for preparing the same and use thereof |
| WO2004073602A2 (en) * | 2002-01-25 | 2004-09-02 | Pharmacia Corporation | Aldosterone blocker therapy to prevent or treat inflammation-related disorders |
| US7456214B2 (en) | 2004-05-03 | 2008-11-25 | Baylor University | Chromene-containing compounds with anti-tubulin and vascular targeting activity |
| MA33451B1 (fr) | 2009-06-26 | 2012-07-03 | Novartis Ag | Dérivés d'imidazolidin-2-one 1,3-disubstitués en tant qu'inhibiteurs de cyp 17 |
| US9132105B2 (en) | 2010-08-04 | 2015-09-15 | Pellficure Pharmaceuticals, Inc. | Treatment of prostate carcinoma |
| JP2013537210A (ja) | 2010-09-16 | 2013-09-30 | ノバルティス アーゲー | １７α−ヒドロキシラーゼ／Ｃ１７，２０−リアーゼ阻害剤 |
| EA023064B1 (ru) | 2011-04-28 | 2016-04-29 | Новартис Аг | ИНГИБИТОРЫ 17α-ГИДРОКСИЛАЗЫ/C-ЛИАЗЫ |
| AU2014241816B9 (en) | 2013-03-14 | 2019-02-14 | Pellficure Pharmaceuticals Inc. | Novel therapy for prostate carcinoma |
| CA2960750A1 (en) | 2014-09-12 | 2016-03-17 | Pellficure Pharmaceuticals, Inc. | Compositions and methods for treatment of prostate carcinoma |
| WO2018080933A1 (en) | 2016-10-24 | 2018-05-03 | Pellficure Pharmaceuticals Inc. | Pharmaceutical compositions of 5-hydroxy-2-methylnaphthalene-1, 4-dione |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5681566A (en) * | 1979-12-05 | 1981-07-03 | Yoshitomi Pharmaceut Ind Ltd | Imidazole derivative |
| ZA825413B (en) * | 1981-08-26 | 1983-06-29 | Pfizer | Thromboxane synthetase inhibitors, processes for their production, and pharmaceutical compositions comprising them |
| US4540705A (en) * | 1983-03-14 | 1985-09-10 | Sterling Drug Inc. | Antidepressant imidazolines and related compounds |
| PH22076A (en) * | 1983-08-25 | 1988-05-20 | Daiichi Seiyaku Co | Benzocycloalkane derivative |
| JPS61186348A (ja) * | 1985-02-14 | 1986-08-20 | Dai Ichi Seiyaku Co Ltd | ナフタレン誘導体 |
| US4661596A (en) * | 1985-02-21 | 1987-04-28 | American Home Products Corporation | Quinolinyl (or pyridinyl) methoxy substituted naphthalene compounds as antiallergic agents |
| DE3508905A1 (de) * | 1985-03-13 | 1986-09-18 | Hoechst Ag, 6230 Frankfurt | Neue imidazolylverbindungen und verfahren zu ihrer herstellung |
| MX13484A (es) * | 1987-10-19 | 1993-05-01 | Pfizer | Procedimiento para la obtencion de tetralinas, cromanos y compuestos relacionados, sustituidos |
| JPH06166674A (ja) * | 1992-12-01 | 1994-06-14 | Tokyo Tanabe Co Ltd | テトラリン化合物 |
| JP3338905B2 (ja) * | 1993-05-13 | 2002-10-28 | 帝国臓器製薬株式会社 | ６位置換ステロイド誘導体 |
| CN1131944A (zh) * | 1993-09-30 | 1996-09-25 | 山之内制药株式会社 | 唑类衍生物和它的药物组合物 |
| FR2787451B1 (fr) * | 1998-12-18 | 2001-01-26 | Adir | Nouveaux composes imidazoliniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
-
1998
- 1998-10-01 AT AT98945556T patent/ATE264304T1/de not_active IP Right Cessation
- 1998-10-01 CA CA002298527A patent/CA2298527A1/en not_active Abandoned
- 1998-10-01 EP EP98945556A patent/EP1028110B1/de not_active Expired - Lifetime
- 1998-10-01 DK DK98945556T patent/DK1028110T3/da active
- 1998-10-01 NZ NZ501822A patent/NZ501822A/en unknown
- 1998-10-01 KR KR1019997005209A patent/KR20000069426A/ko not_active Ceased
- 1998-10-01 IL IL13348398A patent/IL133483A0/xx unknown
- 1998-10-01 DE DE69823222T patent/DE69823222T2/de not_active Expired - Fee Related
- 1998-10-01 HU HU0004037A patent/HUP0004037A3/hu unknown
- 1998-10-01 ZA ZA988954A patent/ZA988954B/xx unknown
- 1998-10-01 RU RU99127323/04A patent/RU2203890C2/ru not_active IP Right Cessation
- 1998-10-01 AU AU92810/98A patent/AU743405B2/en not_active Ceased
- 1998-10-01 CN CN98808436A patent/CN1117732C/zh not_active Expired - Fee Related
- 1998-10-01 ES ES98945556T patent/ES2218853T3/es not_active Expired - Lifetime
- 1998-10-01 WO PCT/JP1998/004426 patent/WO1999018075A1/ja not_active Ceased
-
2000
- 2000-02-01 FI FI20000207A patent/FI20000207A7/fi not_active Application Discontinuation
- 2000-03-10 NO NO20001289A patent/NO315044B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK1028110T3 (da) | 2004-07-19 |
| KR20000069426A (ko) | 2000-11-25 |
| NZ501822A (en) | 2001-12-21 |
| WO1999018075A1 (en) | 1999-04-15 |
| CN1268120A (zh) | 2000-09-27 |
| FI20000207L (fi) | 2000-02-01 |
| NO315044B1 (no) | 2003-06-30 |
| ZA988954B (en) | 1999-04-12 |
| AU9281098A (en) | 1999-04-27 |
| EP1028110B1 (de) | 2004-04-14 |
| IL133483A0 (en) | 2001-04-30 |
| NO20001289L (no) | 2000-03-10 |
| CN1117732C (zh) | 2003-08-13 |
| ES2218853T3 (es) | 2004-11-16 |
| CA2298527A1 (en) | 1999-04-15 |
| RU2203890C2 (ru) | 2003-05-10 |
| EP1028110A1 (de) | 2000-08-16 |
| HUP0004037A2 (hu) | 2001-10-28 |
| AU743405B2 (en) | 2002-01-24 |
| FI20000207A7 (fi) | 2000-02-01 |
| EP1028110A4 (de) | 2001-05-23 |
| HUP0004037A3 (en) | 2002-03-28 |
| DE69823222D1 (de) | 2004-05-19 |
| DE69823222T2 (de) | 2005-04-14 |
| NO20001289D0 (no) | 2000-03-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1028110 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |