DK1028110T3 - Hidtil ukendte dihydronaphthalenforbindelser og fremgangsmåde til fremstilling deraf - Google Patents
Hidtil ukendte dihydronaphthalenforbindelser og fremgangsmåde til fremstilling derafInfo
- Publication number
- DK1028110T3 DK1028110T3 DK98945556T DK98945556T DK1028110T3 DK 1028110 T3 DK1028110 T3 DK 1028110T3 DK 98945556 T DK98945556 T DK 98945556T DK 98945556 T DK98945556 T DK 98945556T DK 1028110 T3 DK1028110 T3 DK 1028110T3
- Authority
- DK
- Denmark
- Prior art keywords
- inhibiting activity
- cancer
- preparation
- new
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP28426397 | 1997-10-02 | ||
| PCT/JP1998/004426 WO1999018075A1 (fr) | 1997-10-02 | 1998-10-01 | Nouveaux composes a base de dihydronaphtalene et leur procede de production |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1028110T3 true DK1028110T3 (da) | 2004-07-19 |
Family
ID=17676271
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98945556T DK1028110T3 (da) | 1997-10-02 | 1998-10-01 | Hidtil ukendte dihydronaphthalenforbindelser og fremgangsmåde til fremstilling deraf |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP1028110B1 (da) |
| KR (1) | KR20000069426A (da) |
| CN (1) | CN1117732C (da) |
| AT (1) | ATE264304T1 (da) |
| AU (1) | AU743405B2 (da) |
| CA (1) | CA2298527A1 (da) |
| DE (1) | DE69823222T2 (da) |
| DK (1) | DK1028110T3 (da) |
| ES (1) | ES2218853T3 (da) |
| FI (1) | FI20000207A (da) |
| HU (1) | HUP0004037A3 (da) |
| IL (1) | IL133483A0 (da) |
| NO (1) | NO315044B1 (da) |
| NZ (1) | NZ501822A (da) |
| RU (1) | RU2203890C2 (da) |
| WO (1) | WO1999018075A1 (da) |
| ZA (1) | ZA988954B (da) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100287366B1 (ko) | 1997-11-24 | 2001-04-16 | 윤순조 | 엠피이지 방식을 이용한 휴대용 음향 재생장치 및 방법 |
| US7001926B2 (en) | 2000-03-10 | 2006-02-21 | Oxigene, Inc. | Tubulin binding agents and corresponding prodrug constructs |
| TWI283669B (en) * | 1999-06-10 | 2007-07-11 | Allergan Inc | Compounds and method of treatment having agonist-like activity selective at alpha 2B or 2B/2C adrenergic receptors |
| US6849656B1 (en) | 1999-09-17 | 2005-02-01 | Baylor University | Indole-containing and combretastatin-related anti-mitotic and anti-tubulin polymerization agents |
| EP1227086B1 (en) * | 1999-10-22 | 2006-03-29 | Takeda Pharmaceutical Company Limited | 1-substituted phenyl-1-(1h-imidazol-4-yl) alcohols, process for producing the same and use thereof |
| JP4520012B2 (ja) * | 1999-10-22 | 2010-08-04 | 武田薬品工業株式会社 | １−置換−１−（１ｈ−イミダゾール−４−イル）メタノール類 |
| JP4616454B2 (ja) * | 1999-10-22 | 2011-01-19 | 武田薬品工業株式会社 | １−置換フェニル−１−（１ｈ−イミダゾール−４−イル）アルコール類、その製造法および用途 |
| US7091240B2 (en) | 2000-03-10 | 2006-08-15 | Oxigene, Inc. | Tubulin binding ligands and corresponding prodrug constructs |
| AU4352701A (en) | 2000-03-10 | 2001-09-24 | Univ Baylor | Tubulin binding ligands and corresponding prodrug constructs |
| IL155624A0 (en) | 2000-11-17 | 2003-11-23 | Takeda Chemical Industries Ltd | Novel imidazole derivatives, production method thereof and use thereof |
| ATE502030T1 (de) | 2000-11-20 | 2011-04-15 | Takeda Pharmaceutical | Imidazolderivate, verfahren zu deren herstellung und deren verwendung |
| CA2431171A1 (en) | 2000-12-08 | 2002-06-13 | Takeda Chemical Industries, Ltd. | Substituted thiazole derivatives bearing 3-pyridyl groups, process for preparing the same and use thereof |
| BR0307413A (pt) * | 2002-01-25 | 2005-05-24 | Pharmacia Corp | Terapêutica com bloqueadores de aldosterona para prevenção ou tratamento de patologias relacionadas com inflamação |
| US7456214B2 (en) | 2004-05-03 | 2008-11-25 | Baylor University | Chromene-containing compounds with anti-tubulin and vascular targeting activity |
| DK2445903T3 (da) | 2009-06-26 | 2014-06-23 | Novartis Ag | 1,3-Disubstituerede imidazolidin-2-on-derivater som CYP17-inhibitorer |
| US9132105B2 (en) | 2010-08-04 | 2015-09-15 | Pellficure Pharmaceuticals, Inc. | Treatment of prostate carcinoma |
| JP2013537210A (ja) | 2010-09-16 | 2013-09-30 | ノバルティス アーゲー | １７α−ヒドロキシラーゼ／Ｃ１７，２０−リアーゼ阻害剤 |
| JP6002210B2 (ja) | 2011-04-28 | 2016-10-05 | ノバルティス アーゲー | １７α−ヒドロキシラーゼ／Ｃ１７，２０−リアーゼ阻害剤 |
| EP2968219B1 (en) | 2013-03-14 | 2019-04-24 | Pellficure Pharmaceuticals, Inc. | Novel therapy for prostate carcinoma |
| EP3191087A1 (en) | 2014-09-12 | 2017-07-19 | Pellficure Pharmaceuticals, Inc. | Compositions and methods for treatment of prostate carcinoma |
| AU2017350690A1 (en) | 2016-10-24 | 2019-06-13 | Pellficure Pharmaceuticals Inc. | Pharmaceutical compositions of 5-hydroxy-2-methylnaphthalene-1, 4-dione |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5681566A (en) * | 1979-12-05 | 1981-07-03 | Yoshitomi Pharmaceut Ind Ltd | Imidazole derivative |
| ZA825413B (en) * | 1981-08-26 | 1983-06-29 | Pfizer | Thromboxane synthetase inhibitors, processes for their production, and pharmaceutical compositions comprising them |
| US4540705A (en) * | 1983-03-14 | 1985-09-10 | Sterling Drug Inc. | Antidepressant imidazolines and related compounds |
| PH22076A (en) * | 1983-08-25 | 1988-05-20 | Daiichi Seiyaku Co | Benzocycloalkane derivative |
| JPS61186348A (ja) * | 1985-02-14 | 1986-08-20 | Dai Ichi Seiyaku Co Ltd | ナフタレン誘導体 |
| DE3508905A1 (de) * | 1985-03-13 | 1986-09-18 | Hoechst Ag, 6230 Frankfurt | Neue imidazolylverbindungen und verfahren zu ihrer herstellung |
| JPH06166674A (ja) * | 1992-12-01 | 1994-06-14 | Tokyo Tanabe Co Ltd | テトラリン化合物 |
| JP3338905B2 (ja) * | 1993-05-13 | 2002-10-28 | 帝国臓器製薬株式会社 | ６位置換ステロイド誘導体 |
| AU679119B2 (en) * | 1993-09-30 | 1997-06-19 | Yamanouchi Pharmaceutical Co., Ltd. | Azole derivative and pharmaceutical composition thereof |
| FR2787451B1 (fr) * | 1998-12-18 | 2001-01-26 | Adir | Nouveaux composes imidazoliniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
-
1998
- 1998-10-01 AT AT98945556T patent/ATE264304T1/de not_active IP Right Cessation
- 1998-10-01 EP EP98945556A patent/EP1028110B1/en not_active Expired - Lifetime
- 1998-10-01 DK DK98945556T patent/DK1028110T3/da active
- 1998-10-01 ES ES98945556T patent/ES2218853T3/es not_active Expired - Lifetime
- 1998-10-01 NZ NZ501822A patent/NZ501822A/en unknown
- 1998-10-01 RU RU99127323/04A patent/RU2203890C2/ru not_active IP Right Cessation
- 1998-10-01 HU HU0004037A patent/HUP0004037A3/hu unknown
- 1998-10-01 KR KR1019997005209A patent/KR20000069426A/ko not_active Application Discontinuation
- 1998-10-01 CN CN98808436A patent/CN1117732C/zh not_active Expired - Fee Related
- 1998-10-01 ZA ZA988954A patent/ZA988954B/xx unknown
- 1998-10-01 WO PCT/JP1998/004426 patent/WO1999018075A1/ja active Search and Examination
- 1998-10-01 AU AU92810/98A patent/AU743405B2/en not_active Ceased
- 1998-10-01 IL IL13348398A patent/IL133483A0/xx unknown
- 1998-10-01 CA CA002298527A patent/CA2298527A1/en not_active Abandoned
- 1998-10-01 DE DE69823222T patent/DE69823222T2/de not_active Expired - Fee Related
-
2000
- 2000-02-01 FI FI20000207A patent/FI20000207A/fi not_active Application Discontinuation
- 2000-03-10 NO NO20001289A patent/NO315044B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69823222D1 (de) | 2004-05-19 |
| RU2203890C2 (ru) | 2003-05-10 |
| NO20001289D0 (no) | 2000-03-10 |
| ZA988954B (en) | 1999-04-12 |
| CN1268120A (zh) | 2000-09-27 |
| KR20000069426A (ko) | 2000-11-25 |
| IL133483A0 (en) | 2001-04-30 |
| NO315044B1 (no) | 2003-06-30 |
| CA2298527A1 (en) | 1999-04-15 |
| EP1028110B1 (en) | 2004-04-14 |
| EP1028110A4 (en) | 2001-05-23 |
| ATE264304T1 (de) | 2004-04-15 |
| ES2218853T3 (es) | 2004-11-16 |
| WO1999018075A1 (fr) | 1999-04-15 |
| AU743405B2 (en) | 2002-01-24 |
| NZ501822A (en) | 2001-12-21 |
| DE69823222T2 (de) | 2005-04-14 |
| NO20001289L (no) | 2000-03-10 |
| CN1117732C (zh) | 2003-08-13 |
| HUP0004037A2 (hu) | 2001-10-28 |
| FI20000207A (fi) | 2000-02-01 |
| HUP0004037A3 (en) | 2002-03-28 |
| AU9281098A (en) | 1999-04-27 |
| EP1028110A1 (en) | 2000-08-16 |
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