ATE502030T1 - Imidazolderivate, verfahren zu deren herstellung und deren verwendung - Google Patents
Imidazolderivate, verfahren zu deren herstellung und deren verwendungInfo
- Publication number
- ATE502030T1 ATE502030T1 AT01982839T AT01982839T ATE502030T1 AT E502030 T1 ATE502030 T1 AT E502030T1 AT 01982839 T AT01982839 T AT 01982839T AT 01982839 T AT01982839 T AT 01982839T AT E502030 T1 ATE502030 T1 AT E502030T1
- Authority
- AT
- Austria
- Prior art keywords
- ring
- chem
- production
- alkyl group
- membered
- Prior art date
Links
- RAXXELZNTBOGNW-UHFFFAOYSA-N 1H-imidazole Chemical class C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 title 1
- 229940079865 intestinal antiinfectives imidazole derivative Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 206010006187 Breast cancer Diseases 0.000 abstract 1
- 208000026310 Breast neoplasm Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 206010036976 Prostatism Diseases 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000006165 cyclic alkyl group Chemical group 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 150000003431 steroids Chemical class 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000353634 | 2000-11-20 | ||
| JP2000382056 | 2000-12-15 | ||
| PCT/JP2001/010079 WO2002040470A1 (fr) | 2000-11-20 | 2001-11-19 | Derives de l'imidazole, leur procede de preparation et leur application |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE502030T1 true ATE502030T1 (de) | 2011-04-15 |
Family
ID=26604319
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01982839T ATE502030T1 (de) | 2000-11-20 | 2001-11-19 | Imidazolderivate, verfahren zu deren herstellung und deren verwendung |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6960586B2 (de) |
| EP (1) | EP1344777B1 (de) |
| AT (1) | ATE502030T1 (de) |
| AU (1) | AU2002214320A1 (de) |
| CA (1) | CA2429437A1 (de) |
| DE (1) | DE60144246D1 (de) |
| WO (1) | WO2002040470A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003267728A1 (en) * | 2002-10-18 | 2004-05-04 | Pfizer Products Inc. | Cannabinoid receptor ligands and uses thereof |
| EP1830845A2 (de) * | 2004-11-09 | 2007-09-12 | Shering Corporation | Verbessertes dosierschema von temozolomid zur behandlung von krebs auf grundlage des mgmt-spiegels eines patienten |
| US20070111979A1 (en) * | 2005-11-07 | 2007-05-17 | Walter Robert Bishop | Methods of treating cell proliferative disorders using a compressed temozolomide dosing schedule |
| WO2007146136A2 (en) * | 2006-06-12 | 2007-12-21 | Merck & Co., Inc. | Ophthalmic compositions for treating ocular hypertension |
| EP2157972A1 (de) * | 2007-05-08 | 2010-03-03 | Schering Corporation | Behandlungsverfahren mit intravenösen temozolomid enthaltenden formulierungen |
| US8180029B2 (en) | 2007-06-28 | 2012-05-15 | Voxer Ip Llc | Telecommunication and multimedia management method and apparatus |
| EP2588104B1 (de) * | 2010-07-01 | 2014-12-10 | Merck Sharp & Dohme Corp. | Positive allosterische isoindolon-m1-rezeptormodulatoren |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ221729A (en) | 1986-09-15 | 1989-07-27 | Janssen Pharmaceutica Nv | Imidazolyl methyl-substituted benzimidazole derivatives and pharmaceutical compositions |
| CA1326234C (en) | 1987-04-22 | 1994-01-18 | Michael R. Angelastro | 17.beta.-(cyclopropylamino)androst-5-en-3.beta.-ol and related compoundsuseful as_c__-__ lyase inhibitors |
| US4966898A (en) | 1989-08-15 | 1990-10-30 | Merrell Dow Pharmaceuticals Inc. | 4-substituted 17β-(cyclopropylamino)androst-5-en-3β-ol and related compounds useful as C17-20 lyase inhibitors |
| AU1449292A (en) | 1991-02-27 | 1992-10-06 | New York University | Anti-testosterone compounds and method of use thereof |
| EP0573534B1 (de) | 1991-03-01 | 1998-12-23 | Electrostatic Technology, Inc. | Pulverbeschichtungsverfahren zur herstellung von leiterplatten und ähnlichen |
| US5457102A (en) | 1994-07-07 | 1995-10-10 | Janssen Pharmaceutica, N.V. | Pyrroloimidazolyl and imidazopyridinyl substituted 1H-benzimidazole derivatives |
| ES2138618T3 (es) | 1992-03-31 | 2000-01-16 | Btg Int Ltd | Esteroides 17-sustituidos utiles en el tratamiento del cancer. |
| GB9310635D0 (en) | 1993-05-21 | 1993-07-07 | Glaxo Group Ltd | Chemical compounds |
| AU679119B2 (en) | 1993-09-30 | 1997-06-19 | Yamanouchi Pharmaceutical Co., Ltd. | Azole derivative and pharmaceutical composition thereof |
| AU3846395A (en) | 1994-11-07 | 1996-05-31 | Janssen Pharmaceutica N.V. | Compositions comprising carbazoles and cyclodextrins |
| AU6015796A (en) | 1995-06-14 | 1997-01-15 | Yamanouchi Pharmaceutical Co., Ltd. | Fused imidazole derivatives and medicinal composition thereof |
| AU6229698A (en) | 1997-02-21 | 1998-09-09 | Takeda Chemical Industries Ltd. | Fused ring compounds, process for producing the same and use thereof |
| WO1999018075A1 (fr) | 1997-10-02 | 1999-04-15 | Yukijirushi Nyugyo Kabushiki Kaisha | Nouveaux composes a base de dihydronaphtalene et leur procede de production |
| WO1999054309A1 (en) | 1998-04-23 | 1999-10-28 | Takeda Chemical Industries, Ltd. | Naphthalene derivatives, their production and use |
| AU7950100A (en) * | 1999-10-22 | 2001-05-08 | Takeda Chemical Industries Ltd. | 1-substituted phenyl-1-(1h-imidazol-4-yl) alcohols, process for producing the same and use thereof |
| ATE320420T1 (de) * | 1999-10-22 | 2006-04-15 | Takeda Pharmaceutical | Verfahren zur herstellung von optisch aktiven naphthalinderivaten und darin eingesetzte optische resolver |
| PE20010781A1 (es) * | 1999-10-22 | 2001-08-08 | Takeda Chemical Industries Ltd | Compuestos 1-(1h-imidazol-4-il)-1-(naftil-2-sustituido)etanol, su produccion y utilizacion |
-
2001
- 2001-11-19 US US10/416,998 patent/US6960586B2/en not_active Expired - Fee Related
- 2001-11-19 CA CA002429437A patent/CA2429437A1/en not_active Abandoned
- 2001-11-19 EP EP01982839A patent/EP1344777B1/de not_active Expired - Lifetime
- 2001-11-19 DE DE60144246T patent/DE60144246D1/de not_active Expired - Lifetime
- 2001-11-19 WO PCT/JP2001/010079 patent/WO2002040470A1/ja active Application Filing
- 2001-11-19 AT AT01982839T patent/ATE502030T1/de not_active IP Right Cessation
- 2001-11-19 AU AU2002214320A patent/AU2002214320A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE60144246D1 (de) | 2011-04-28 |
| US20040024039A1 (en) | 2004-02-05 |
| US6960586B2 (en) | 2005-11-01 |
| EP1344777A1 (de) | 2003-09-17 |
| AU2002214320A1 (en) | 2002-05-27 |
| CA2429437A1 (en) | 2002-05-23 |
| WO2002040470A1 (fr) | 2002-05-23 |
| EP1344777B1 (de) | 2011-03-16 |
| EP1344777A4 (de) | 2007-05-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |