NZ205513A - Isoquinoline-4-carboxylic acid derivatives and pharmaceutical compositions containing such - Google Patents
Isoquinoline-4-carboxylic acid derivatives and pharmaceutical compositions containing suchInfo
- Publication number
- NZ205513A NZ205513A NZ205513A NZ20551383A NZ205513A NZ 205513 A NZ205513 A NZ 205513A NZ 205513 A NZ205513 A NZ 205513A NZ 20551383 A NZ20551383 A NZ 20551383A NZ 205513 A NZ205513 A NZ 205513A
- Authority
- NZ
- New Zealand
- Prior art keywords
- denotes
- isoquinoline
- hydrogen
- carboxylic acid
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19823233424 DE3233424A1 (de) | 1982-09-09 | 1982-09-09 | Isochinolinderivate, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ205513A true NZ205513A (en) | 1986-05-09 |
Family
ID=6172780
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ205513A NZ205513A (en) | 1982-09-09 | 1983-09-07 | Isoquinoline-4-carboxylic acid derivatives and pharmaceutical compositions containing such |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4673682A (forum.php) |
| EP (1) | EP0105210B1 (forum.php) |
| JP (1) | JPS5967270A (forum.php) |
| KR (1) | KR840006206A (forum.php) |
| AT (1) | ATE25679T1 (forum.php) |
| AU (1) | AU1891683A (forum.php) |
| CA (1) | CA1211445A (forum.php) |
| DE (2) | DE3233424A1 (forum.php) |
| DK (1) | DK408083A (forum.php) |
| ES (1) | ES8404852A1 (forum.php) |
| FI (1) | FI833200A7 (forum.php) |
| GR (1) | GR79382B (forum.php) |
| HU (1) | HU191094B (forum.php) |
| IL (1) | IL69683A0 (forum.php) |
| NO (1) | NO833217L (forum.php) |
| NZ (1) | NZ205513A (forum.php) |
| PH (1) | PH18186A (forum.php) |
| PT (1) | PT77309B (forum.php) |
| ZA (1) | ZA836663B (forum.php) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4956371A (en) * | 1989-09-19 | 1990-09-11 | Euroceltique, S.A. | Substituted isoquinolines and methods of using same |
| ES2152938T3 (es) * | 1992-09-28 | 2001-02-16 | Hoechst Ag | 1(2h)-isoquinolinas sustituidas antiarritmicas y cardioprotectoras, procedimiento para su produccion, medicamento que las contiene y su uso para la produccion de un medicamento para combatir fallos cardiacos. |
| US5552412A (en) * | 1995-01-09 | 1996-09-03 | Pfizer Inc | 5-substitued-6-cyclic-5,6,7,8-tetrahydronaphthalen2-ol compounds which are useful for treating osteoporosis |
| NZ543448A (en) * | 2003-06-06 | 2009-02-28 | Fibrogen Inc | Nitrogen-containing heteroaryl compounds and their use in increasing endogeneous erythropoietin |
| CN103382216B (zh) * | 2006-01-27 | 2016-04-20 | 菲布罗根有限公司 | 使低氧诱导因子（hif）稳定的氰基异喹啉化合物 |
| US7696223B2 (en) * | 2006-04-04 | 2010-04-13 | Fibrogen, Inc. | Pyrrolo- and Thiazolo-pyridine compounds, and methods of use thereof |
| US8927591B2 (en) | 2008-11-14 | 2015-01-06 | Fibrogen, Inc. | Thiochromene derivatives as HIF hydroxylase inhibitors |
| AU2013229922B2 (en) | 2012-03-09 | 2017-09-28 | Fibrogen, Inc. | 4 -hydroxy- isoquinoline compounds as HIF hydroxylase inhibitors |
| US8883823B2 (en) | 2012-07-16 | 2014-11-11 | Fibrogen, Inc. | Crystalline forms of a prolyl hydroxylase inhibitor |
| KR20210130849A (ko) | 2012-07-16 | 2021-11-01 | 피브로겐, 인크. | 프롤릴 하이드록실라제 억제제 [(4-하이드록시-1-메틸-7-페녹시-아이소퀴놀린-3-카보닐)-아미노]-아세트산의 결정형 |
| US9340511B2 (en) | 2012-07-16 | 2016-05-17 | Fibrogen, Inc. | Process for making isoquinoline compounds |
| WO2014116849A1 (en) | 2013-01-24 | 2014-07-31 | Fibrogen, Inc. | Crystalline forms of {[1-cyano-5-(4-chlorophenoxy)-4-hydroxy-isoquinoline-3-carbonyl]-amino}-acetic acid |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2054482B1 (forum.php) * | 1969-07-11 | 1973-06-08 | Anvar | |
| FR2424270A1 (fr) * | 1978-04-24 | 1979-11-23 | Rhone Poulenc Ind | Nouveaux derives de l'isoquinoleine, leur preparation et les compositions qui les contiennent |
| DE2818423A1 (de) * | 1978-04-27 | 1979-11-08 | Hoechst Ag | Neue isochinolinderivate und verfahren zu ihrer herstellung |
-
1982
- 1982-09-09 DE DE19823233424 patent/DE3233424A1/de not_active Withdrawn
-
1983
- 1983-09-03 EP EP83108697A patent/EP0105210B1/de not_active Expired
- 1983-09-03 AT AT83108697T patent/ATE25679T1/de not_active IP Right Cessation
- 1983-09-03 DE DE8383108697T patent/DE3369983D1/de not_active Expired
- 1983-09-07 IL IL69683A patent/IL69683A0/xx unknown
- 1983-09-07 GR GR72399A patent/GR79382B/el unknown
- 1983-09-07 PH PH29505A patent/PH18186A/en unknown
- 1983-09-07 FI FI833200A patent/FI833200A7/fi not_active Application Discontinuation
- 1983-09-07 ES ES525441A patent/ES8404852A1/es not_active Expired
- 1983-09-07 KR KR1019830004199A patent/KR840006206A/ko not_active Withdrawn
- 1983-09-07 US US06/530,000 patent/US4673682A/en not_active Expired - Fee Related
- 1983-09-07 NZ NZ205513A patent/NZ205513A/en unknown
- 1983-09-08 PT PT77309A patent/PT77309B/pt unknown
- 1983-09-08 CA CA000436316A patent/CA1211445A/en not_active Expired
- 1983-09-08 NO NO833217A patent/NO833217L/no unknown
- 1983-09-08 AU AU18916/83A patent/AU1891683A/en not_active Abandoned
- 1983-09-08 JP JP58164274A patent/JPS5967270A/ja active Pending
- 1983-09-08 HU HU833134A patent/HU191094B/hu unknown
- 1983-09-08 DK DK408083A patent/DK408083A/da not_active Application Discontinuation
- 1983-09-08 ZA ZA836663A patent/ZA836663B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0105210A3 (en) | 1984-10-10 |
| KR840006206A (ko) | 1984-11-22 |
| IL69683A0 (en) | 1983-12-30 |
| ATE25679T1 (de) | 1987-03-15 |
| AU1891683A (en) | 1984-03-15 |
| DE3369983D1 (en) | 1987-04-09 |
| FI833200A7 (fi) | 1984-03-10 |
| PT77309B (de) | 1986-04-18 |
| FI833200A0 (fi) | 1983-09-07 |
| DK408083D0 (da) | 1983-09-08 |
| ES525441A0 (es) | 1984-05-16 |
| JPS5967270A (ja) | 1984-04-16 |
| ZA836663B (en) | 1984-04-25 |
| CA1211445A (en) | 1986-09-16 |
| PT77309A (de) | 1983-10-01 |
| HU191094B (en) | 1987-01-28 |
| DK408083A (da) | 1984-03-10 |
| DE3233424A1 (de) | 1984-03-15 |
| GR79382B (forum.php) | 1984-10-22 |
| ES8404852A1 (es) | 1984-05-16 |
| US4673682A (en) | 1987-06-16 |
| NO833217L (no) | 1984-03-12 |
| EP0105210A2 (de) | 1984-04-11 |
| EP0105210B1 (de) | 1987-03-04 |
| PH18186A (en) | 1985-04-12 |
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