NZ177056A - Certain 9 -(chloro or flruoro)-16( or )-methyl-11 ,17 -dihydroxypregna-1,4-diene-3,20-dione 17 -acylates or 11 ,17 -diacylates and certain preparature processes - Google Patents

Certain 9 -(chloro or flruoro)-16( or )-methyl-11 ,17 -dihydroxypregna-1,4-diene-3,20-dione 17 -acylates or 11 ,17 -diacylates and certain preparature processes

Info

Publication number
NZ177056A
NZ177056A NZ177056A NZ17705675A NZ177056A NZ 177056 A NZ177056 A NZ 177056A NZ 177056 A NZ177056 A NZ 177056A NZ 17705675 A NZ17705675 A NZ 17705675A NZ 177056 A NZ177056 A NZ 177056A
Authority
NZ
New Zealand
Prior art keywords
certain
chloro
methyl
tetrahydropyran
acyloxy
Prior art date
Application number
NZ177056A
Other languages
English (en)
Inventor
J Villax
Original Assignee
Plurichemie Anstalt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Plurichemie Anstalt filed Critical Plurichemie Anstalt
Priority to NZ184973A priority Critical patent/NZ184973A/xx
Publication of NZ177056A publication Critical patent/NZ177056A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
    • C07J7/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa substituted in position 16
    • C07J7/0055—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NZ177056A 1974-03-27 1975-03-26 Certain 9 -(chloro or flruoro)-16( or )-methyl-11 ,17 -dihydroxypregna-1,4-diene-3,20-dione 17 -acylates or 11 ,17 -diacylates and certain preparature processes NZ177056A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NZ184973A NZ184973A (en) 1974-03-27 1975-03-26 9 -(chloro or fluoro)-16( or )-methyl-11 -(tetrahydro-pyran-2'-yloxy)-17 -hydroxypregna-1,4-diene-3,20-diones

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PT6163674 1974-03-27
PT6163774 1974-03-27
PT6163675 1975-03-10

Publications (1)

Publication Number Publication Date
NZ177056A true NZ177056A (en) 1978-09-20

Family

ID=27354092

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ177056A NZ177056A (en) 1974-03-27 1975-03-26 Certain 9 -(chloro or flruoro)-16( or )-methyl-11 ,17 -dihydroxypregna-1,4-diene-3,20-dione 17 -acylates or 11 ,17 -diacylates and certain preparature processes

Country Status (8)

Country Link
BE (1) BE827275A (fr)
CH (2) CH622811A5 (fr)
DK (1) DK153556C (fr)
FR (1) FR2274309A1 (fr)
GB (2) GB1510617A (fr)
IE (2) IE41138B1 (fr)
NZ (1) NZ177056A (fr)
SE (1) SE440656B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR890000664B1 (ko) * 1981-10-19 1989-03-22 바리 안소니 뉴우샘 미분된 베클로메타손 디프로피오네이트 일수화물의 제조방법
IT1285770B1 (it) 1996-10-04 1998-06-18 Nicox Sa Composti corticoidei
CN102516348B (zh) * 2011-11-10 2013-11-13 中国科学院上海有机化学研究所 一种16s-甲基-20s-羟基孕甾化合物、合成方法及其用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1070751A (en) * 1964-01-28 1967-06-01 Glaxo Lab Ltd 17-esters of 17-hydroxy-21-desoxy-steroids
GB1139505A (en) * 1965-06-23 1969-01-08 Glaxo Lab Ltd A process for the production of 17-‡-monoesters of 17-‡-hydroxy-20-keto-steroids
CH481085A (de) * 1965-08-30 1969-11-15 Scherico Ltd Verfahren zur Herstellung von 11B-Hydroxy-17 -alkanoyloxysteroiden der Pregnanreihe
US3383394A (en) * 1965-08-30 1968-05-14 Schering Corp Novel 17-acylating process and products thereof
BE788355A (fr) * 1971-09-07 1973-03-05 Merck Patent Gmbh Esters de 9 alpha-fluoro-16-methylene-prednisolone

Also Published As

Publication number Publication date
DK153556C (da) 1988-12-05
GB1510617A (en) 1978-05-10
IE41137B1 (en) 1979-10-24
SE440656B (sv) 1985-08-12
GB1511820A (en) 1978-05-24
DK153556B (da) 1988-07-25
FR2274309A1 (fr) 1976-01-09
CH622811A5 (fr) 1981-04-30
CH625254A5 (fr) 1981-09-15
FR2274309B1 (fr) 1978-11-24
DK129575A (fr) 1975-09-28
IE41137L (en) 1975-09-27
BE827275A (fr) 1975-07-16
IE41138B1 (en) 1979-10-24
SE7803041L (sv) 1978-03-16

Similar Documents

Publication Publication Date Title
US4695625A (en) Process for the preparation of 16,17 acetals of pregnane derivatives
GB1475795A (en) Steroid 21-thioesters
HU188067B (en) Process for preparing delta 17/20/21-substituted steroids
GB1429922A (en) Steroid acetals processes for their manufacture and preparations containing them
GB1445945A (en) Steroids of the d-homo-pregnane series
NZ177056A (en) Certain 9 -(chloro or flruoro)-16( or )-methyl-11 ,17 -dihydroxypregna-1,4-diene-3,20-dione 17 -acylates or 11 ,17 -diacylates and certain preparature processes
GB1462686A (en) Intermediates for 16-substituted corticoid synthesis
US2875200A (en) 9alpha-halo-11beta, 21-dihydroxy-4, 17(20)-pregnadiene-3-one compounds and process of preparing thereof
IE32938B1 (en) 17alpha,21-orthocarbonates of steroid-derivatives and process for preparing them
GB1416475A (en) 21-orthoesters of cortical steroids and methods of preparing same
GB924931A (fr)
SE7513200L (sv) Steroid(16alfa,17-b)naftalener
GB1450807A (en) Cardenolide glycosides and process for their manufacture
GB1145336A (en) 17-‡-[3' furyl]-estrogens and process for the preparation thereof
IE800050L (en) 21-alkylated steroids
GB1244560A (en) Halogenated steroids and process for the manufacture thereof
GB1273024A (en) 07alpha-ALKADIENYL STEROIDS
GB898295A (en) Improvements in or relating to steroids and the manufacture thereof
GB1272688A (en) Sulphamido-steroids and the preparation thereof
GB1514621A (en) 13-ethynyl-and 13-(2-halovinyl)-steroids and their preparation
WO2003010181A1 (fr) PROCEDE STEREOSELECTIF DE PRODUCTION DE 6α-FLUORPREGNANES ET D'INTERMEDIAIRES
GB1317185A (en) Acyloxy-3alpha-hydroxy-pregnones
ES368120A1 (es) Procedimiento para la preparacion de derivados de 14 alfa, 17 alfa, 17 alfa-metilendioxipregnano.
GB1502513A (en) Steroid(16,17-b)dioxanes
US2923722A (en) 2-lower-alkyl-9alpha-halo-4-pregnenes