NO995564L - Fremgangsmåte og konstruksjon for inhibisjon av cellemigrering - Google Patents

Fremgangsmåte og konstruksjon for inhibisjon av cellemigrering

Info

Publication number
NO995564L
NO995564L NO995564A NO995564A NO995564L NO 995564 L NO995564 L NO 995564L NO 995564 A NO995564 A NO 995564A NO 995564 A NO995564 A NO 995564A NO 995564 L NO995564 L NO 995564L
Authority
NO
Norway
Prior art keywords
construction
cell migration
migration inhibition
inhibition
cell
Prior art date
Application number
NO995564A
Other languages
English (en)
Norwegian (no)
Other versions
NO995564D0 (no
Inventor
Paulus Hubertus Andreas Quax
Johan Hendrikus Verheijen
Original Assignee
Tno
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tno filed Critical Tno
Publication of NO995564D0 publication Critical patent/NO995564D0/no
Publication of NO995564L publication Critical patent/NO995564L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114—Kunitz type inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114—Kunitz type inhibitors
    • C07K14/8117—Bovine/basic pancreatic trypsin inhibitor (BPTI, aprotinin)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8146—Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO995564A 1997-05-12 1999-11-12 Fremgangsmåte og konstruksjon for inhibisjon av cellemigrering NO995564L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97201423 1997-05-12
PCT/NL1998/000259 WO1998051788A2 (fr) 1997-05-12 1998-05-11 Procede et construction pouvant inhiber une migration cellulaire

Publications (2)

Publication Number Publication Date
NO995564D0 NO995564D0 (no) 1999-11-12
NO995564L true NO995564L (no) 2000-01-11

Family

ID=8228315

Family Applications (1)

Application Number Title Priority Date Filing Date
NO995564A NO995564L (no) 1997-05-12 1999-11-12 Fremgangsmåte og konstruksjon for inhibisjon av cellemigrering

Country Status (7)

Country Link
EP (1) EP0981606A2 (fr)
JP (1) JP2001525669A (fr)
AU (1) AU7553698A (fr)
CA (1) CA2289117A1 (fr)
NO (1) NO995564L (fr)
NZ (1) NZ500656A (fr)
WO (1) WO1998051788A2 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999055365A1 (fr) 1998-04-30 1999-11-04 Cornell Research Foundation, Inc. Vecteurs adenoviraux avec proteines a deux types de genes de fibre
CA2342396A1 (fr) 1998-09-11 2000-03-23 Genvec, Inc. Adenovirus a ciblage altnernatif
DE10020125A1 (de) * 2000-04-18 2001-10-25 Friedrich Schiller Uni Jena Bu Agens für den postoperativen Einsatz nach Entfernung von Knochentumoren
EP1366175B1 (fr) * 2000-12-18 2008-01-23 Arriva Pharmaceuticals, Inc. Inhibiteurs de protease multifonctionnels et leur utilisation dans le traitement de maladies
US7247704B2 (en) 2000-12-18 2007-07-24 Arriva Pharmaceuticals, Inc. Multifunctional protease inhibitors and their use in treatment of disease
EP1903113A1 (fr) * 2000-12-18 2008-03-26 Arriva Pharmaceuticals, Inc. Inhibiteurs de protéase multifonctionnels et leur utilisation dans le traitement de maladies
EP2172552A3 (fr) * 2001-10-11 2010-07-21 Merck Sharp & Dohme Corp. Acide nucléique recombinant comprenant des régions de AD6
AU2002337840B2 (en) 2001-10-11 2007-08-09 Msd Italia S.R.L. Hepatitis C virus vaccine

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE243754T1 (de) * 1987-05-21 2003-07-15 Micromet Ag Multifunktionelle proteine mit vorbestimmter zielsetzung
US5504001A (en) * 1987-11-25 1996-04-02 Zymogenetics, Inc. Hybrid plasminogen activator
DK0383599T3 (da) * 1989-02-17 1996-08-05 Merck & Co Inc Protein-anticancermiddel
JP2877509B2 (ja) * 1989-05-19 1999-03-31 アムジエン・インコーポレーテツド メタロプロテイナーゼ阻害剤
ES2060134T3 (es) * 1989-05-26 1994-11-16 Univ Washington Inhibidor de tejido de metaloproteasas (timp-2).
AU657087B2 (en) * 1989-12-22 1995-03-02 Seragen Incorporated Hybrid molecules having translocation region and cell-binding region
WO1991012328A1 (fr) * 1990-02-15 1991-08-22 Fowlkes Dana M Reactifs entierement synthetiques a affinite specifique
GB2246779B (en) * 1990-08-03 1994-08-17 Delta Biotechnology Ltd Tumour-associated protease inhibitors targeted to tumour cells
EP0730660A4 (fr) * 1993-10-29 1998-02-25 Incyte Pharma Inc Proteines chimeres contenant des variantes de la protease nexine-1
WO1995013091A1 (fr) * 1993-11-12 1995-05-18 International Technology Management Associates, Ltd. Procedes pour la reparation de tissu conjonctif
US5550213A (en) * 1993-12-27 1996-08-27 Rutgers, The State University Of New Jersey Inhibitors of urokinase plasminogen activator
WO1995021601A2 (fr) * 1994-01-11 1995-08-17 Protein Engineering Corporation Proteines de 'domaine de kunitz' a activite antikallikreine, et leurs analogues
AU2342995A (en) * 1994-04-22 1995-11-16 Jorgen Gliemann Peptides binding to the alpha2-macroglobulin receptor/low density lipoprotein receptor-related protein
US5712149A (en) * 1995-02-03 1998-01-27 Cell Genesys, Inc. Chimeric receptor molecules for delivery of co-stimulatory signals
US5843724A (en) * 1995-04-27 1998-12-01 Rutgers University Chimeric nucleic acids and proteins for inhibiting HIV-1 expression
US5726050A (en) * 1995-06-20 1998-03-10 Massachusetts Institute Of Technology Z-DNA binding protein and applications
WO1997025422A1 (fr) * 1996-01-08 1997-07-17 Nissin Food Products Co., Ltd. Inhibiteur de metastases cancereuses

Also Published As

Publication number Publication date
AU7553698A (en) 1998-12-08
JP2001525669A (ja) 2001-12-11
CA2289117A1 (fr) 1998-11-19
NO995564D0 (no) 1999-11-12
WO1998051788A3 (fr) 1999-05-20
EP0981606A2 (fr) 2000-03-01
NZ500656A (en) 2001-11-30
WO1998051788A2 (fr) 1998-11-19

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Legal Events

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