NO984524L - Amfipatiske molekyler som kolesterol- og andre lipoidopptaksinhibitorer - Google Patents
Amfipatiske molekyler som kolesterol- og andre lipoidopptaksinhibitorerInfo
- Publication number
- NO984524L NO984524L NO984524A NO984524A NO984524L NO 984524 L NO984524 L NO 984524L NO 984524 A NO984524 A NO 984524A NO 984524 A NO984524 A NO 984524A NO 984524 L NO984524 L NO 984524L
- Authority
- NO
- Norway
- Prior art keywords
- cholesterol
- amphipathic
- molecules
- uptake inhibitors
- amphipathic molecules
- Prior art date
Links
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title abstract 10
- 235000012000 cholesterol Nutrition 0.000 title abstract 5
- 239000003112 inhibitor Substances 0.000 title abstract 3
- 150000002632 lipids Chemical class 0.000 title abstract 3
- 230000015572 biosynthetic process Effects 0.000 abstract 3
- 102000006410 Apoproteins Human genes 0.000 abstract 1
- 108010083590 Apoproteins Proteins 0.000 abstract 1
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 229940121710 HMGCoA reductase inhibitor Drugs 0.000 abstract 1
- 208000035150 Hypercholesterolemia Diseases 0.000 abstract 1
- 208000031226 Hyperlipidaemia Diseases 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 235000005911 diet Nutrition 0.000 abstract 1
- 230000037213 diet Effects 0.000 abstract 1
- 235000018823 dietary intake Nutrition 0.000 abstract 1
- 239000002471 hydroxymethylglutaryl coenzyme A reductase inhibitor Substances 0.000 abstract 1
- 230000000968 intestinal effect Effects 0.000 abstract 1
- 210000000936 intestine Anatomy 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cardiology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9606686.5A GB9606686D0 (en) | 1996-03-29 | 1996-03-29 | Medical use |
| GBGB9626920.4A GB9626920D0 (en) | 1996-12-24 | 1996-12-24 | Medical use |
| PCT/IB1997/000379 WO1997036927A1 (fr) | 1996-03-29 | 1997-03-27 | Molecules amphipathiques agissant comme inhibiteurs de l'absorption du cholesterol et d'autres lipides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO984524D0 NO984524D0 (no) | 1998-09-28 |
| NO984524L true NO984524L (no) | 1998-11-30 |
Family
ID=26309021
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO984524A NO984524L (no) | 1996-03-29 | 1998-09-28 | Amfipatiske molekyler som kolesterol- og andre lipoidopptaksinhibitorer |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20010005714A1 (fr) |
| EP (1) | EP0889906A1 (fr) |
| JP (1) | JP2000509020A (fr) |
| CN (1) | CN1109047C (fr) |
| AU (1) | AU710061B2 (fr) |
| CA (1) | CA2249459A1 (fr) |
| NO (1) | NO984524L (fr) |
| NZ (1) | NZ331980A (fr) |
| WO (1) | WO1997036927A1 (fr) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6037323A (en) * | 1997-09-29 | 2000-03-14 | Jean-Louis Dasseux | Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders |
| US6046166A (en) | 1997-09-29 | 2000-04-04 | Jean-Louis Dasseux | Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders |
| US6004925A (en) | 1997-09-29 | 1999-12-21 | J. L. Dasseux | Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders |
| EP1090634A1 (fr) * | 1999-10-01 | 2001-04-11 | Helmut Hauser | Agents pour diminuer l'absorption du cholestérol et des lipides |
| US7250304B2 (en) | 2000-03-31 | 2007-07-31 | The Regents Of The University Of California | Functional assay of high-density lipoprotein |
| US7166578B2 (en) | 2000-08-24 | 2007-01-23 | The Regents Of The University Of California | Orally administered peptides synergize statin activity |
| US6664230B1 (en) * | 2000-08-24 | 2003-12-16 | The Regents Of The University Of California | Orally administered peptides to ameliorate atherosclerosis |
| US7723303B2 (en) | 2000-08-24 | 2010-05-25 | The Regents Of The University Of California | Peptides and peptide mimetics to treat pathologies characterized by an inflammatory response |
| AU2007237157B2 (en) * | 2000-08-24 | 2009-04-09 | The Regents Of The University Of California | Peptides that ameliorate atherosclerosis |
| US7144862B2 (en) | 2000-08-24 | 2006-12-05 | The Regents Of The University Of California | Orally administered peptides to ameliorate atherosclerosis |
| US8568766B2 (en) | 2000-08-24 | 2013-10-29 | Gattadahalli M. Anantharamaiah | Peptides and peptide mimetics to treat pathologies associated with eye disease |
| US7148197B2 (en) * | 2000-08-24 | 2006-12-12 | The Regents Of The University Of California | Orally administered small peptides synergize statin activity |
| US7199102B2 (en) * | 2000-08-24 | 2007-04-03 | The Regents Of The University Of California | Orally administered peptides synergize statin activity |
| CA2430122C (fr) | 2000-11-28 | 2010-08-24 | Mitsubishi Pharma Corporation | Agent contre l'obesite et les aliments sante |
| US6930085B2 (en) | 2002-04-05 | 2005-08-16 | The Regents Of The University Of California | G-type peptides to ameliorate atherosclerosis |
| CA2486127C (fr) | 2002-05-17 | 2014-03-11 | Esperion Therapeutics, Inc. | Methode de traitement de troubles dyslipidemiques |
| AU2003290825C1 (en) * | 2002-11-13 | 2009-12-10 | The Uab Research Foundation | Synthetic single domain polypeptides mimicking apolipoprotein E and methods of use |
| DE10343815A1 (de) * | 2003-09-22 | 2005-04-14 | B.R.A.H.M.S Ag | Verfahren zur Diagnose von Erkrankungen unter Bestimmung von Apolipoprotein C-I, und dessen Verwendung in der Therapie von Erkrankungen |
| CN101065137A (zh) * | 2004-09-16 | 2007-10-31 | 加利福尼亚大学董事会 | 用于改善动脉粥样硬化和其它病变的g型多肽和其它剂 |
| RU2414236C2 (ru) | 2004-12-06 | 2011-03-20 | Зе Риджентс Оф Зи Юнивесити Оф Кэлифонье | Способ улучшения структуры и/или функций артериол |
| MX2007013430A (es) * | 2005-04-29 | 2008-03-19 | Univ California | Peptidos y peptidos mimeticos para tratar patologias caracterizadas por una respuesta inflamatoria. |
| US20080293639A1 (en) * | 2005-04-29 | 2008-11-27 | The Regents Of The University Of California | Peptides and peptide mimetics to treat pathologies characterized by an inflammatory response |
| WO2007000924A1 (fr) * | 2005-06-28 | 2007-01-04 | Osaka University | Préparation pharmaceutique comprenant une substance susceptible d'inhiber ou de promouvoir l'activité de la progranuline et méthode de criblage pour la recherche d'une substance susceptible d'inhiber ou de promouvoir l'activité de la progranuline |
| EP1836906B1 (fr) * | 2006-03-24 | 2009-07-01 | Unilever N.V. | Produit alimentaire sain |
| BRPI0707045A2 (pt) * | 2006-03-24 | 2011-04-12 | Unilever Nv | produto alimentìcio e uso de um produto alimentìcio |
| BRPI0707042A2 (pt) * | 2006-03-24 | 2011-04-12 | Unilever Nv | produto alimentìcio e uso |
| AU2007284801A1 (en) | 2006-08-08 | 2008-02-21 | The Regents Of The University Of Californina | Salicylanilides enhance oral delivery of therapeutic peptides |
| US8557767B2 (en) | 2007-08-28 | 2013-10-15 | Uab Research Foundation | Synthetic apolipoprotein E mimicking polypeptides and methods of use |
| JP2010538005A (ja) | 2007-08-28 | 2010-12-09 | ユーエービー リサーチ ファウンデーション | 合成アポリポ蛋白質ｅ模倣ポリペプチドおよび使用方法 |
| US9173890B2 (en) | 2007-09-20 | 2015-11-03 | Abbott Cardiovascular Systems Inc. | Sustained release of Apo A-I mimetic peptides and methods of treatment |
| US8101565B2 (en) * | 2007-09-20 | 2012-01-24 | Abbott Cardiovascular Systems Inc. | Sustained release of Apo A-I mimetic peptides and methods of treatment |
| US8044021B2 (en) | 2007-09-20 | 2011-10-25 | Abbott Cardiovascular Systems Inc. | Sustained release of apo A-I mimetic peptides and methods of treatment |
| US7985727B1 (en) | 2007-09-20 | 2011-07-26 | Abbott Cardiovascular Systems Inc. | Apo A-I mimetic peptides and methods of treatment |
| US7985728B1 (en) | 2007-09-20 | 2011-07-26 | Abbott Cardiovascular Systems Inc. | Sustained release of Apo A-I mimetic peptides and methods of treatment |
| BR112017001860A2 (pt) | 2014-07-31 | 2018-02-27 | Uab Research Foundation | peptídeo sintético, composição farmacêutica, métodos, regime de dosagem, e, anticorpo monoclonal |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU7797594A (en) * | 1993-09-15 | 1995-04-03 | Cv Therapeutics, Inc. | Protein for mediating cholesterol absorption and an inhibitor thereof |
| US5373009A (en) * | 1994-02-02 | 1994-12-13 | American Home Products Corporation | Dibenzofuranyl esters of N-heterocyclic carboxylic acids |
-
1997
- 1997-03-27 WO PCT/IB1997/000379 patent/WO1997036927A1/fr not_active Application Discontinuation
- 1997-03-27 CN CN97194265A patent/CN1109047C/zh not_active Expired - Fee Related
- 1997-03-27 NZ NZ331980A patent/NZ331980A/xx unknown
- 1997-03-27 AU AU21741/97A patent/AU710061B2/en not_active Ceased
- 1997-03-27 JP JP9535088A patent/JP2000509020A/ja active Pending
- 1997-03-27 EP EP97914509A patent/EP0889906A1/fr not_active Withdrawn
- 1997-03-27 CA CA002249459A patent/CA2249459A1/fr not_active Abandoned
-
1998
- 1998-09-28 US US09/162,095 patent/US20010005714A1/en not_active Abandoned
- 1998-09-28 NO NO984524A patent/NO984524L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2000509020A (ja) | 2000-07-18 |
| CN1216995A (zh) | 1999-05-19 |
| AU710061B2 (en) | 1999-09-09 |
| WO1997036927A1 (fr) | 1997-10-09 |
| NO984524D0 (no) | 1998-09-28 |
| NZ331980A (en) | 2000-09-29 |
| CN1109047C (zh) | 2003-05-21 |
| US20010005714A1 (en) | 2001-06-28 |
| CA2249459A1 (fr) | 1997-10-09 |
| EP0889906A1 (fr) | 1999-01-13 |
| AU2174197A (en) | 1997-10-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |