NO984344D0 - Ny asymmetriske syntese av R-<alfa>-propylpiperonyalamin og dets analoger - Google Patents

Ny asymmetriske syntese av R-<alfa>-propylpiperonyalamin og dets analoger

Info

Publication number
NO984344D0
NO984344D0 NO984344A NO984344A NO984344D0 NO 984344 D0 NO984344 D0 NO 984344D0 NO 984344 A NO984344 A NO 984344A NO 984344 A NO984344 A NO 984344A NO 984344 D0 NO984344 D0 NO 984344D0
Authority
NO
Norway
Prior art keywords
propylpiperonyalamine
alfa
analogs
asymmetric synthesis
new asymmetric
Prior art date
Application number
NO984344A
Other languages
English (en)
Norwegian (no)
Other versions
NO984344L (no
Inventor
Hui-Yin Li
Luigi Anzalone
Robert Eugebe Waltermire
Original Assignee
Du Pont Merck Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont Merck Pharma filed Critical Du Pont Merck Pharma
Publication of NO984344L publication Critical patent/NO984344L/no
Publication of NO984344D0 publication Critical patent/NO984344D0/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58Radicals substituted by nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO984344A 1996-03-22 1998-09-18 Ny asymmetriske syntese av R-<alfa>-propylpiperonyalamin og dets analoger NO984344D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1395596P 1996-03-22 1996-03-22
PCT/US1997/003466 WO1997034887A1 (en) 1996-03-22 1997-03-17 NOVEL ASYMMETRIC SYNTHESIS OF R-α-PROPYL-PIPERONYL AMINE AND ITS ANALOGS

Publications (2)

Publication Number Publication Date
NO984344L NO984344L (no) 1998-09-18
NO984344D0 true NO984344D0 (no) 1998-09-18

Family

ID=21762727

Family Applications (1)

Application Number Title Priority Date Filing Date
NO984344A NO984344D0 (no) 1996-03-22 1998-09-18 Ny asymmetriske syntese av R-<alfa>-propylpiperonyalamin og dets analoger

Country Status (23)

Country Link
US (1) US5932749A (cs)
EP (1) EP0888329A1 (cs)
JP (1) JP2000506891A (cs)
KR (1) KR20000064735A (cs)
CN (1) CN1218463A (cs)
AR (1) AR006521A1 (cs)
AU (1) AU719633B2 (cs)
BR (1) BR9708233A (cs)
CA (1) CA2249401A1 (cs)
CZ (1) CZ295098A3 (cs)
EA (1) EA001207B1 (cs)
EE (1) EE9800299A (cs)
HR (1) HRP970165A2 (cs)
IL (1) IL126223A0 (cs)
LT (1) LT4540B (cs)
LV (1) LV12259B (cs)
NO (1) NO984344D0 (cs)
NZ (1) NZ331875A (cs)
PL (1) PL329070A1 (cs)
SI (1) SI9720023A (cs)
SK (1) SK127398A3 (cs)
WO (1) WO1997034887A1 (cs)
ZA (1) ZA972342B (cs)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5587299A (en) 1998-08-31 2000-03-21 Du Pont Pharmaceuticals Company An efficient process for the preparation of a human leukocyte elastase inhibitor
US6825351B2 (en) * 2001-09-12 2004-11-30 Anormed, Inc. Synthesis of enantiomerically pure amino-substituted fused bicyclic rings
WO2010077798A2 (en) * 2008-12-15 2010-07-08 Taigen Biotechnology Co., Ltd. Stereoselective synthesis of piperidine derivatives
AR090100A1 (es) 2012-02-21 2014-10-22 Celgene Corp Procesos para la preparacion de la (s)-1-(3-etoxi-4-metoxifenil)-2-metanosulfoniletilamina
US9126906B2 (en) 2012-02-21 2015-09-08 Celgene Corporation Asymmetric synthetic processes for the preparation of aminosulfone compounds
US11357742B2 (en) 2015-12-14 2022-06-14 X4 Pharmaceuticals, Inc. Methods for treating cancer
WO2017106328A1 (en) 2015-12-14 2017-06-22 X4 Pharmaceuticals, Inc. Methods for treating cancer
CA3009176A1 (en) 2015-12-22 2017-06-29 X4 Pharmaceuticals, Inc. Methods for treating immunodeficiency disease
CN109153722A (zh) 2016-04-08 2019-01-04 X4 制药有限公司 用于治疗癌症的方法
CN116554168B (zh) 2016-06-21 2025-09-23 X4制药有限公司 Cxcr4抑制剂及其用途
JP7084624B2 (ja) 2016-06-21 2022-06-15 エックス4 ファーマシューティカルズ, インコーポレイテッド Cxcr4阻害剤およびその使用
US11332470B2 (en) 2016-06-21 2022-05-17 X4 Pharmaceuticals, Inc. CXCR4 inhibitors and uses thereof
US10548889B1 (en) 2018-08-31 2020-02-04 X4 Pharmaceuticals, Inc. Compositions of CXCR4 inhibitors and methods of preparation and use
EP4117662A4 (en) 2020-03-10 2024-04-03 X4 Pharmaceuticals, Inc. METHODS OF TREATING NEUTROPENIA
MX2024002291A (es) 2021-09-01 2024-06-28 Empathbio Inc Sintesis de mdma o sus isomeros de mdma opticamente activos (r)- o (s).
EP4401725A1 (en) * 2021-09-17 2024-07-24 atai Life Sciences AG Preparation of optically active enantiomers of piperonyl amines by resolution of the diastereomeric salts
EP4408832A1 (en) 2021-10-01 2024-08-07 Empathibio, Inc. Novel prodrugs of mdma, mda, and derivatives thereof
EP4457222A2 (en) 2021-12-28 2024-11-06 EmpathBio, Inc. Nitric oxide releasing prodrugs of mda and mdma

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3819438A1 (de) * 1987-06-30 1989-01-19 Basf Ag Verfahren zur herstellung von optisch aktiven 1-arylethylaminen
IL99658A0 (en) * 1990-10-15 1992-08-18 Merck & Co Inc Substituted azetidinones and pharmaceutical compositions containing them
US5149838A (en) * 1991-09-20 1992-09-22 Merck & Co., Inc. Intermediates for substituted azetidinones useful as anti-inflammatory and antidegenerative agents

Also Published As

Publication number Publication date
LV12259B (en) 1999-09-20
NO984344L (no) 1998-09-18
SI9720023A (sl) 1999-04-30
AR006521A1 (es) 1999-09-08
CN1218463A (zh) 1999-06-02
BR9708233A (pt) 2000-01-04
EP0888329A1 (en) 1999-01-07
IL126223A0 (en) 1999-05-09
EA199800844A1 (ru) 1999-02-25
EE9800299A (et) 1999-06-15
ZA972342B (en) 1998-09-18
US5932749A (en) 1999-08-03
JP2000506891A (ja) 2000-06-06
CZ295098A3 (cs) 1999-03-17
LT4540B (lt) 1999-08-25
AU719633B2 (en) 2000-05-11
CA2249401A1 (en) 1997-09-25
WO1997034887A1 (en) 1997-09-25
EA001207B1 (ru) 2000-12-25
KR20000064735A (ko) 2000-11-06
HRP970165A2 (en) 1998-04-30
LV12259A (lv) 1999-04-20
LT98132A (en) 1999-03-25
PL329070A1 (en) 1999-03-15
SK127398A3 (en) 1999-04-13
NZ331875A (en) 2000-01-28
AU2196897A (en) 1997-10-10

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