NO984071L - Anvendelse av hemmere av natrium-hydrogen-veksler for fremstilling av et medikament for redusering av u°nskede virkninger av stoffer pÕ hjertet - Google Patents

Anvendelse av hemmere av natrium-hydrogen-veksler for fremstilling av et medikament for redusering av u°nskede virkninger av stoffer pÕ hjertet

Info

Publication number
NO984071L
NO984071L NO984071A NO984071A NO984071L NO 984071 L NO984071 L NO 984071L NO 984071 A NO984071 A NO 984071A NO 984071 A NO984071 A NO 984071A NO 984071 L NO984071 L NO 984071L
Authority
NO
Norway
Prior art keywords
medicament
sodium
manufacture
reducing
heart
Prior art date
Application number
NO984071A
Other languages
English (en)
Norwegian (no)
Other versions
NO984071D0 (no
Inventor
Hans Jochen Lang
Hartmut Ruetten
Holger Heitsch
Wolfgang Linz
Bernward Schoelkens
Original Assignee
Hoechst Marion Roussel De Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel De Gmbh filed Critical Hoechst Marion Roussel De Gmbh
Publication of NO984071D0 publication Critical patent/NO984071D0/no
Publication of NO984071L publication Critical patent/NO984071L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
NO984071A 1997-09-04 1998-09-04 Anvendelse av hemmere av natrium-hydrogen-veksler for fremstilling av et medikament for redusering av u°nskede virkninger av stoffer pÕ hjertet NO984071L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19738604A DE19738604A1 (de) 1997-09-04 1997-09-04 Die Verwendung von Hemmern des Natrium-Wasserstoff-Austauschers zur Herstellung eines Medikaments zur Verminderung der Giftigkeit cardiotoxischer Stoffe

Publications (2)

Publication Number Publication Date
NO984071D0 NO984071D0 (no) 1998-09-04
NO984071L true NO984071L (no) 1999-03-05

Family

ID=7841131

Family Applications (1)

Application Number Title Priority Date Filing Date
NO984071A NO984071L (no) 1997-09-04 1998-09-04 Anvendelse av hemmere av natrium-hydrogen-veksler for fremstilling av et medikament for redusering av u°nskede virkninger av stoffer pÕ hjertet

Country Status (23)

Country Link
US (1) US6462024B1 (ru)
EP (1) EP0916337A3 (ru)
JP (1) JP4555409B2 (ru)
KR (1) KR19990029520A (ru)
CN (1) CN1195508C (ru)
AR (1) AR015718A1 (ru)
AU (1) AU753899B2 (ru)
BR (1) BR9803319A (ru)
CA (1) CA2246633A1 (ru)
CZ (1) CZ280898A3 (ru)
DE (1) DE19738604A1 (ru)
HK (1) HK1018212A1 (ru)
HR (1) HRP980488A2 (ru)
HU (1) HUP9802005A3 (ru)
IL (1) IL126068A0 (ru)
NO (1) NO984071L (ru)
NZ (1) NZ331682A (ru)
PL (1) PL328366A1 (ru)
RU (1) RU2252754C2 (ru)
SK (1) SK121198A3 (ru)
TR (1) TR199801728A2 (ru)
TW (1) TW592693B (ru)
ZA (1) ZA988066B (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7375138B2 (en) 2002-05-18 2008-05-20 Sanofi-Aventis Deutschland Gmbh Pentafluorosulfanylbenzoylguanidines, processes for their preparation, their use as medicaments or diagnostic aids, and medicaments comprising them
FR2840302B1 (fr) * 2002-06-03 2004-07-16 Aventis Pharma Sa Derives d'isoindolones, procede de preparation et intermediaire de ce procede a titre de medicaments et compositions pharmaceutiques les renfermant
US6878748B2 (en) 2002-06-13 2005-04-12 Aventis Pharma Deutschland Gmbh Fluorinated cycloalkyl-derivatized benzoylguanidines, process for their preparation, their uses as medicament, and medicament containing them
ATE404533T1 (de) * 2003-05-06 2008-08-15 Merck Patent Gmbh Verfahren zur kristallisation von guanidinium- salzen
CN112107568B (zh) * 2019-06-19 2022-03-25 北京龙嘉博创医药科技有限公司 二芳基酰胺类化合物及其应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3929582A1 (de) * 1989-09-06 1991-03-07 Hoechst Ag Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament
DE4127026A1 (de) * 1991-08-16 1993-02-18 Boehringer Ingelheim Kg Neue pyrazinderivate, ihre herstellung und verwendung
CZ284456B6 (cs) * 1992-02-15 1998-12-16 Hoechst Aktiengesellschaft Aminosubstituované benzoylguanidiny, způsob jejich přípravy, jejich použití jako léčiv a léčivo, které je obsahuje
EP0589336B1 (de) * 1992-09-22 1997-01-08 Hoechst Aktiengesellschaft Benzoylguanidine, Verfahren zu ihrer Herstellung, sowie ihre Verwendung als Antiarrhythmika
TW250479B (ru) * 1992-12-15 1995-07-01 Hoechst Ag
DE4337609A1 (de) * 1993-11-04 1995-05-11 Boehringer Ingelheim Kg Neue Pyrazincarboxamidderivate, ihre Herstellung und ihre Verwendung in Arzneimitteln
DE4422685A1 (de) * 1994-06-29 1996-01-04 Hoechst Ag Ortho-amino-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4428480A1 (de) * 1994-08-11 1996-03-07 Hoechst Ag Substituierte Benzoesäureester, Verfahren zu ihrer Herstellung und ihre Verwendung zur Synthese von Inhibitoren des zellulären Na·+·/H·+·-Austauschs
DE4430861A1 (de) * 1994-08-31 1996-03-07 Merck Patent Gmbh Heterocyclyl-benzoylguanidine
DE4441880A1 (de) * 1994-11-24 1996-05-30 Hoechst Ag Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19734693A1 (de) * 1997-08-11 1998-01-22 Hoechst Marion Roussel De Gmbh Verwendung von Cariporide als Inhibitor des zellulären NA+/H+-Exchangers (NHE) zur Herstellung eines Medikaments zur Behandlung von cardialen und nichtcardialen Krankheiten

Also Published As

Publication number Publication date
JP4555409B2 (ja) 2010-09-29
JPH11180896A (ja) 1999-07-06
HRP980488A2 (en) 1999-06-30
KR19990029520A (ko) 1999-04-26
EP0916337A2 (de) 1999-05-19
CN1195508C (zh) 2005-04-06
CA2246633A1 (en) 1999-03-04
DE19738604A1 (de) 1999-03-11
HK1018212A1 (en) 1999-12-17
ZA988066B (en) 1999-03-11
SK121198A3 (en) 1999-03-12
TR199801728A2 (xx) 1999-04-21
PL328366A1 (en) 1999-03-15
US6462024B1 (en) 2002-10-08
RU2252754C2 (ru) 2005-05-27
TW592693B (en) 2004-06-21
EP0916337A3 (de) 2004-03-17
NO984071D0 (no) 1998-09-04
AU753899B2 (en) 2002-10-31
BR9803319A (pt) 2000-03-21
HUP9802005A2 (hu) 1999-04-28
AR015718A1 (es) 2001-05-16
NZ331682A (en) 2001-08-31
HU9802005D0 (en) 1998-11-30
HUP9802005A3 (en) 2005-06-28
IL126068A0 (en) 1999-05-09
AU8307398A (en) 1999-03-18
CN1209995A (zh) 1999-03-10
CZ280898A3 (cs) 1999-03-17

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application