NO980032L - Biologisk aktiv blanding omfattende cyklosporin - Google Patents

Biologisk aktiv blanding omfattende cyklosporin

Info

Publication number
NO980032L
NO980032L NO980032A NO980032A NO980032L NO 980032 L NO980032 L NO 980032L NO 980032 A NO980032 A NO 980032A NO 980032 A NO980032 A NO 980032A NO 980032 L NO980032 L NO 980032L
Authority
NO
Norway
Prior art keywords
cyclosporine
biologically active
phase
specific
active mixture
Prior art date
Application number
NO980032A
Other languages
English (en)
Other versions
NO980032D0 (no
Inventor
Kaare Larsson
Helena Ljusberg-Wahren
Original Assignee
Gs Dev Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gs Dev Ab filed Critical Gs Dev Ab
Publication of NO980032D0 publication Critical patent/NO980032D0/no
Publication of NO980032L publication Critical patent/NO980032L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1274—Non-vesicle bilayer structures, e.g. liquid crystals, tubules, cubic phases, cochleates; Sponge phases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Biologisk aktiv blanding basert på en L2-fase av et spesifikt monoglycerid, et spesifikt triglycerid og en spesifikk polar væske, og et syklosporin som er løst eller dispergert i nevnte L2-fase som den biologisk aktive substans. En fremgangsmåte for fremstilling av nevnte blanding, hvori syklosporinet blir tilsatt til L2-fasen før, under eller etter dannelsen av samme. Anvendelse av nevnte L2-fase for innkapsling av et syklosporin for fremstilling av et oralt administrer- bart preparat for anvendelse som et immunosuppressivt middel.
NO980032A 1995-07-06 1998-01-05 Biologisk aktiv blanding omfattende cyklosporin NO980032L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9502472A SE504582C2 (sv) 1995-07-06 1995-07-06 Cyklosporinkomposition baserad på en L2-fas
PCT/SE1996/000893 WO1997002042A1 (en) 1995-07-06 1996-07-02 Biologically active composition comprising cyclosporine

Publications (2)

Publication Number Publication Date
NO980032D0 NO980032D0 (no) 1998-01-05
NO980032L true NO980032L (no) 1998-03-03

Family

ID=20398887

Family Applications (1)

Application Number Title Priority Date Filing Date
NO980032A NO980032L (no) 1995-07-06 1998-01-05 Biologisk aktiv blanding omfattende cyklosporin

Country Status (12)

Country Link
EP (1) EP0873133B1 (no)
JP (1) JPH11508592A (no)
AT (1) ATE213951T1 (no)
AU (1) AU6374596A (no)
BR (1) BR9609332A (no)
CA (1) CA2226219A1 (no)
CZ (1) CZ1998A3 (no)
DE (2) DE873133T1 (no)
ES (1) ES2123477T3 (no)
NO (1) NO980032L (no)
SE (1) SE504582C2 (no)
WO (1) WO1997002042A1 (no)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE511313C2 (sv) 1997-01-13 1999-09-06 Gs Dev Ab Komposition med reglerad frisättning innefattande fettsyraester av diacylglycerol
CA2313024C (en) 1997-12-10 2008-06-03 Severson, Mary L. Pharmaceutical compositions containing an omega-3 fatty acid oil
BR9916063A (pt) * 1998-12-11 2002-01-22 Pharmasolutions Inc Composições auto-emulsificantes para medicamentos fracamente solúveis em água
CA2466432A1 (en) 2001-11-08 2003-05-15 Atrium Medical Corporation Intraluminal device with a coating containing a therapeutic agent
WO2007011385A2 (en) 2004-09-28 2007-01-25 Atrium Medical Corporation Heat cured gel and method of making
US9000040B2 (en) 2004-09-28 2015-04-07 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
WO2006036967A1 (en) 2004-09-28 2006-04-06 Atrium Medical Corporation Solubilizing a drug for use in a coating
US9801982B2 (en) 2004-09-28 2017-10-31 Atrium Medical Corporation Implantable barrier device
US9012506B2 (en) 2004-09-28 2015-04-21 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
US8312836B2 (en) 2004-09-28 2012-11-20 Atrium Medical Corporation Method and apparatus for application of a fresh coating on a medical device
US8367099B2 (en) 2004-09-28 2013-02-05 Atrium Medical Corporation Perforated fatty acid films
US9427423B2 (en) 2009-03-10 2016-08-30 Atrium Medical Corporation Fatty-acid based particles
US9278161B2 (en) 2005-09-28 2016-03-08 Atrium Medical Corporation Tissue-separating fatty acid adhesion barrier
WO2007047781A2 (en) 2005-10-15 2007-04-26 Atrium Medical Corporation Hydrophobic cross-linked gels for bioabsorbable drug carrier coatings
US9492596B2 (en) 2006-11-06 2016-11-15 Atrium Medical Corporation Barrier layer with underlying medical device and one or more reinforcing support structures
EP2083875B1 (en) 2006-11-06 2013-03-27 Atrium Medical Corporation Coated surgical mesh
ES2400964T3 (es) 2007-04-04 2013-04-15 Sigmoid Pharma Limited Composiciones famacéuticas de ciclosporina
CN102470106B (zh) 2009-05-18 2015-09-23 希格默伊德药业有限公司 包含油滴的组合物
US20110038910A1 (en) 2009-08-11 2011-02-17 Atrium Medical Corporation Anti-infective antimicrobial-containing biomaterials
IN2012DN00781A (no) 2009-08-12 2015-06-26 Sigmoid Pharma Ltd
EP2593141B1 (en) 2010-07-16 2018-07-04 Atrium Medical Corporation Composition and methods for altering the rate of hydrolysis of cured oil-based materials
GB201020032D0 (en) 2010-11-25 2011-01-12 Sigmoid Pharma Ltd Composition
JO3337B1 (ar) 2010-12-13 2019-03-13 Debiopharm Sa تركيبات صيدلية تشمل أليسبوريفير
US9867880B2 (en) 2012-06-13 2018-01-16 Atrium Medical Corporation Cured oil-hydrogel biomaterial compositions for controlled drug delivery
GB201304662D0 (en) 2013-03-14 2013-05-01 Sigmoid Pharma Ltd Compositions
ES2858517T3 (es) * 2014-11-07 2021-09-30 Sublimity Therapeutics Ltd Composiciones que comprenden ciclosporina

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI65914C (fi) * 1978-03-07 1984-08-10 Sandoz Ag Foerfarande foer framstaellning av farmaceutiska kompositionerinnehaollande cyklosporin a
SE457693B (sv) * 1986-07-01 1989-01-23 Drilletten Ab Komposition med reglerad frigoering vari ett biologiskt material aer loest eller dispergerat i en l2-fas
GB9113872D0 (en) * 1991-06-27 1991-08-14 Sandoz Ag Improvements in or relating to organic compounds

Also Published As

Publication number Publication date
ES2123477T1 (es) 1999-01-16
ES2123477T3 (es) 2002-08-01
AU6374596A (en) 1997-02-05
ATE213951T1 (de) 2002-03-15
DE69619700D1 (de) 2002-04-11
JPH11508592A (ja) 1999-07-27
DE873133T1 (de) 1999-05-06
CA2226219A1 (en) 1997-01-23
SE9502472L (sv) 1997-01-07
SE9502472D0 (sv) 1995-07-06
EP0873133A1 (en) 1998-10-28
BR9609332A (pt) 1999-05-25
NO980032D0 (no) 1998-01-05
EP0873133B1 (en) 2002-03-06
CZ1998A3 (cs) 1998-06-17
DE69619700T2 (de) 2002-10-24
WO1997002042A1 (en) 1997-01-23
SE504582C2 (sv) 1997-03-10

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