ES2123477T1 - Composicion biologicamente activa que comprende ciclosporina. - Google Patents
Composicion biologicamente activa que comprende ciclosporina.Info
- Publication number
- ES2123477T1 ES2123477T1 ES96923154T ES96923154T ES2123477T1 ES 2123477 T1 ES2123477 T1 ES 2123477T1 ES 96923154 T ES96923154 T ES 96923154T ES 96923154 T ES96923154 T ES 96923154T ES 2123477 T1 ES2123477 T1 ES 2123477T1
- Authority
- ES
- Spain
- Prior art keywords
- biologically active
- phase
- active composition
- cyclosporine
- specific
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1274—Non-vesicle bilayer structures, e.g. liquid crystals, tubules, cubic phases, cochleates; Sponge phases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Transplantation (AREA)
- Dispersion Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Abstract
SE DESCRIBE UNA COMPOSICION BIOLOGICAMENTE ACTIVA BASADA EN UNA FASE L2 DE UN MONOGLICERIDO ESPECIFICO, UN TRIGLICERIDO ESPECIFICO Y UN LIQUIDO POLAR ESPECIFICO, ESTANDO UNA CICLOSPORINA DISUELTA O DISPERSADA EN DICHA FASE L2 COMO SUSTANCIA BIOLOGICAMENTE ACTIVA. SE DESCRIBE UN PROCEDIMIENTO PARA LA PREPARACION DE DICHA COMPOSICION, EN EL CUAL SE AÑADE LA CICLOSPORINA A LA FASE L2 ANTES, DURANTE O DESPUES DE LA FORMACION DE LA MISMA. SE DESCRIBE EL USO DE DICHA FASE L2 PARA LA ENCAPSULACION DE UNA CICLOSPORINA PARA LA FABRICACION DE UNA PREPARACION PARA LA ADMINISTRACION ORAL PARA SU UTILIZACION COMO AGENTE INMUNOSUPRESOR.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9502472A SE504582C2 (sv) | 1995-07-06 | 1995-07-06 | Cyklosporinkomposition baserad på en L2-fas |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2123477T1 true ES2123477T1 (es) | 1999-01-16 |
| ES2123477T3 ES2123477T3 (es) | 2002-08-01 |
Family
ID=20398887
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES96923154T Expired - Lifetime ES2123477T3 (es) | 1995-07-06 | 1996-07-02 | Composicion biologicamente activa que comprende ciclosporina. |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0873133B1 (es) |
| JP (1) | JPH11508592A (es) |
| AT (1) | ATE213951T1 (es) |
| AU (1) | AU6374596A (es) |
| BR (1) | BR9609332A (es) |
| CA (1) | CA2226219A1 (es) |
| CZ (1) | CZ1998A3 (es) |
| DE (2) | DE69619700T2 (es) |
| ES (1) | ES2123477T3 (es) |
| NO (1) | NO980032L (es) |
| SE (1) | SE504582C2 (es) |
| WO (1) | WO1997002042A1 (es) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE511313C2 (sv) | 1997-01-13 | 1999-09-06 | Gs Dev Ab | Komposition med reglerad frisättning innefattande fettsyraester av diacylglycerol |
| CA2313024C (en) | 1997-12-10 | 2008-06-03 | Severson, Mary L. | Pharmaceutical compositions containing an omega-3 fatty acid oil |
| PL348193A1 (en) * | 1998-12-11 | 2002-05-06 | Pharmasolutions | Self-emulsifying compositions for drugs poorly soluble in water |
| CA2508907A1 (en) | 2001-11-08 | 2003-05-15 | Atrium Medical Corporation | Intraluminal device with a coating containing a therapeutic agent |
| US8263102B2 (en) | 2004-09-28 | 2012-09-11 | Atrium Medical Corporation | Drug delivery coating for use with a stent |
| US9801913B2 (en) | 2004-09-28 | 2017-10-31 | Atrium Medical Corporation | Barrier layer |
| US9801982B2 (en) | 2004-09-28 | 2017-10-31 | Atrium Medical Corporation | Implantable barrier device |
| US8312836B2 (en) | 2004-09-28 | 2012-11-20 | Atrium Medical Corporation | Method and apparatus for application of a fresh coating on a medical device |
| US8367099B2 (en) | 2004-09-28 | 2013-02-05 | Atrium Medical Corporation | Perforated fatty acid films |
| US9000040B2 (en) | 2004-09-28 | 2015-04-07 | Atrium Medical Corporation | Cross-linked fatty acid-based biomaterials |
| US9012506B2 (en) | 2004-09-28 | 2015-04-21 | Atrium Medical Corporation | Cross-linked fatty acid-based biomaterials |
| US9427423B2 (en) | 2009-03-10 | 2016-08-30 | Atrium Medical Corporation | Fatty-acid based particles |
| US9278161B2 (en) | 2005-09-28 | 2016-03-08 | Atrium Medical Corporation | Tissue-separating fatty acid adhesion barrier |
| CA2626030A1 (en) | 2005-10-15 | 2007-04-26 | Atrium Medical Corporation | Hydrophobic cross-linked gels for bioabsorbable drug carrier coatings |
| US9492596B2 (en) | 2006-11-06 | 2016-11-15 | Atrium Medical Corporation | Barrier layer with underlying medical device and one or more reinforcing support structures |
| WO2008057344A2 (en) | 2006-11-06 | 2008-05-15 | Atrium Medical Corporation | Coated surgical mesh |
| WO2008122967A2 (en) | 2007-04-04 | 2008-10-16 | Sigmoid Pharma Limited | An oral pharmaceutical composition |
| US9278070B2 (en) | 2009-05-18 | 2016-03-08 | Sigmoid Pharma Limited | Composition comprising oil drops |
| US20110038910A1 (en) | 2009-08-11 | 2011-02-17 | Atrium Medical Corporation | Anti-infective antimicrobial-containing biomaterials |
| EP2464341B1 (en) | 2009-08-12 | 2022-07-06 | Sublimity Therapeutics Limited | Immunomodulatory compositions comprising a polymer matrix and an oil phase |
| WO2012009707A2 (en) | 2010-07-16 | 2012-01-19 | Atrium Medical Corporation | Composition and methods for altering the rate of hydrolysis of cured oil-based materials |
| GB201020032D0 (en) | 2010-11-25 | 2011-01-12 | Sigmoid Pharma Ltd | Composition |
| JO3337B1 (ar) * | 2010-12-13 | 2019-03-13 | Debiopharm Sa | تركيبات صيدلية تشمل أليسبوريفير |
| US9867880B2 (en) | 2012-06-13 | 2018-01-16 | Atrium Medical Corporation | Cured oil-hydrogel biomaterial compositions for controlled drug delivery |
| GB201304662D0 (en) | 2013-03-14 | 2013-05-01 | Sigmoid Pharma Ltd | Compositions |
| EA036036B1 (ru) * | 2014-11-07 | 2020-09-16 | Сигмойд Фарма Лимитед | Композиции, содержащие циклоспорин |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI65914C (fi) * | 1978-03-07 | 1984-08-10 | Sandoz Ag | Foerfarande foer framstaellning av farmaceutiska kompositionerinnehaollande cyklosporin a |
| SE457693B (sv) * | 1986-07-01 | 1989-01-23 | Drilletten Ab | Komposition med reglerad frigoering vari ett biologiskt material aer loest eller dispergerat i en l2-fas |
| GB9113872D0 (en) * | 1991-06-27 | 1991-08-14 | Sandoz Ag | Improvements in or relating to organic compounds |
-
1995
- 1995-07-06 SE SE9502472A patent/SE504582C2/sv not_active IP Right Cessation
-
1996
- 1996-07-02 ES ES96923154T patent/ES2123477T3/es not_active Expired - Lifetime
- 1996-07-02 DE DE69619700T patent/DE69619700T2/de not_active Expired - Fee Related
- 1996-07-02 AT AT96923154T patent/ATE213951T1/de not_active IP Right Cessation
- 1996-07-02 AU AU63745/96A patent/AU6374596A/en not_active Abandoned
- 1996-07-02 BR BR9609332A patent/BR9609332A/pt not_active Application Discontinuation
- 1996-07-02 EP EP96923154A patent/EP0873133B1/en not_active Expired - Lifetime
- 1996-07-02 WO PCT/SE1996/000893 patent/WO1997002042A1/en not_active Application Discontinuation
- 1996-07-02 CA CA002226219A patent/CA2226219A1/en not_active Abandoned
- 1996-07-02 JP JP9505078A patent/JPH11508592A/ja active Pending
- 1996-07-02 CZ CZ9819A patent/CZ1998A3/cs unknown
- 1996-07-02 DE DE0873133T patent/DE873133T1/de active Pending
-
1998
- 1998-01-05 NO NO980032A patent/NO980032L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0873133B1 (en) | 2002-03-06 |
| ES2123477T3 (es) | 2002-08-01 |
| SE9502472L (sv) | 1997-01-07 |
| CA2226219A1 (en) | 1997-01-23 |
| CZ1998A3 (cs) | 1998-06-17 |
| EP0873133A1 (en) | 1998-10-28 |
| DE69619700D1 (de) | 2002-04-11 |
| BR9609332A (pt) | 1999-05-25 |
| ATE213951T1 (de) | 2002-03-15 |
| SE504582C2 (sv) | 1997-03-10 |
| AU6374596A (en) | 1997-02-05 |
| DE69619700T2 (de) | 2002-10-24 |
| WO1997002042A1 (en) | 1997-01-23 |
| NO980032D0 (no) | 1998-01-05 |
| NO980032L (no) | 1998-03-03 |
| JPH11508592A (ja) | 1999-07-27 |
| DE873133T1 (de) | 1999-05-06 |
| SE9502472D0 (sv) | 1995-07-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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