ES2123477T1 - Composicion biologicamente activa que comprende ciclosporina. - Google Patents
Composicion biologicamente activa que comprende ciclosporina.Info
- Publication number
- ES2123477T1 ES2123477T1 ES96923154T ES96923154T ES2123477T1 ES 2123477 T1 ES2123477 T1 ES 2123477T1 ES 96923154 T ES96923154 T ES 96923154T ES 96923154 T ES96923154 T ES 96923154T ES 2123477 T1 ES2123477 T1 ES 2123477T1
- Authority
- ES
- Spain
- Prior art keywords
- biologically active
- phase
- active composition
- cyclosporine
- specific
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1274—Non-vesicle bilayer structures, e.g. liquid crystals, tubules, cubic phases, cochleates; Sponge phases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Transplantation (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SE DESCRIBE UNA COMPOSICION BIOLOGICAMENTE ACTIVA BASADA EN UNA FASE L2 DE UN MONOGLICERIDO ESPECIFICO, UN TRIGLICERIDO ESPECIFICO Y UN LIQUIDO POLAR ESPECIFICO, ESTANDO UNA CICLOSPORINA DISUELTA O DISPERSADA EN DICHA FASE L2 COMO SUSTANCIA BIOLOGICAMENTE ACTIVA. SE DESCRIBE UN PROCEDIMIENTO PARA LA PREPARACION DE DICHA COMPOSICION, EN EL CUAL SE AÑADE LA CICLOSPORINA A LA FASE L2 ANTES, DURANTE O DESPUES DE LA FORMACION DE LA MISMA. SE DESCRIBE EL USO DE DICHA FASE L2 PARA LA ENCAPSULACION DE UNA CICLOSPORINA PARA LA FABRICACION DE UNA PREPARACION PARA LA ADMINISTRACION ORAL PARA SU UTILIZACION COMO AGENTE INMUNOSUPRESOR.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9502472A SE504582C2 (sv) | 1995-07-06 | 1995-07-06 | Cyklosporinkomposition baserad på en L2-fas |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2123477T1 true ES2123477T1 (es) | 1999-01-16 |
| ES2123477T3 ES2123477T3 (es) | 2002-08-01 |
Family
ID=20398887
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES96923154T Expired - Lifetime ES2123477T3 (es) | 1995-07-06 | 1996-07-02 | Composicion biologicamente activa que comprende ciclosporina. |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0873133B1 (es) |
| JP (1) | JPH11508592A (es) |
| AT (1) | ATE213951T1 (es) |
| AU (1) | AU6374596A (es) |
| BR (1) | BR9609332A (es) |
| CA (1) | CA2226219A1 (es) |
| CZ (1) | CZ1998A3 (es) |
| DE (2) | DE873133T1 (es) |
| ES (1) | ES2123477T3 (es) |
| NO (1) | NO980032L (es) |
| SE (1) | SE504582C2 (es) |
| WO (1) | WO1997002042A1 (es) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE511313C2 (sv) | 1997-01-13 | 1999-09-06 | Gs Dev Ab | Komposition med reglerad frisättning innefattande fettsyraester av diacylglycerol |
| EP1039893B1 (en) | 1997-12-10 | 2011-02-02 | Cyclosporine Therapeutics Limited | Pharmaceutical compositions containing an omega-3 fatty acid oil |
| KR100602725B1 (ko) * | 1998-12-11 | 2006-07-20 | 파마솔루션스, 인코포레이티드 | 물에서 불충분하게 용해되는 약제를 위한 자가-유화용조성물 |
| US8460693B2 (en) | 2001-11-08 | 2013-06-11 | Atrium Medical Corporation | Intraluminal device with a coating containing synthetic fish oil and a therapeutic agent |
| US9801982B2 (en) | 2004-09-28 | 2017-10-31 | Atrium Medical Corporation | Implantable barrier device |
| US9012506B2 (en) | 2004-09-28 | 2015-04-21 | Atrium Medical Corporation | Cross-linked fatty acid-based biomaterials |
| US20060067977A1 (en) | 2004-09-28 | 2006-03-30 | Atrium Medical Corporation | Pre-dried drug delivery coating for use with a stent |
| EP1811935B1 (en) | 2004-09-28 | 2016-03-30 | Atrium Medical Corporation | Heat cured gel and method of making |
| US8312836B2 (en) | 2004-09-28 | 2012-11-20 | Atrium Medical Corporation | Method and apparatus for application of a fresh coating on a medical device |
| US8367099B2 (en) | 2004-09-28 | 2013-02-05 | Atrium Medical Corporation | Perforated fatty acid films |
| US9000040B2 (en) | 2004-09-28 | 2015-04-07 | Atrium Medical Corporation | Cross-linked fatty acid-based biomaterials |
| US9278161B2 (en) | 2005-09-28 | 2016-03-08 | Atrium Medical Corporation | Tissue-separating fatty acid adhesion barrier |
| US8574627B2 (en) | 2006-11-06 | 2013-11-05 | Atrium Medical Corporation | Coated surgical mesh |
| US9427423B2 (en) | 2009-03-10 | 2016-08-30 | Atrium Medical Corporation | Fatty-acid based particles |
| AU2006304590A1 (en) | 2005-10-15 | 2007-04-26 | Atrium Medical Corporation | Hydrophobic cross-linked gels for bioabsorbable drug carrier coatings |
| US9492596B2 (en) | 2006-11-06 | 2016-11-15 | Atrium Medical Corporation | Barrier layer with underlying medical device and one or more reinforcing support structures |
| CN103120653B (zh) | 2007-04-04 | 2015-09-30 | 希格默伊德药业有限公司 | 一种口服药物组合物 |
| EP3300723A1 (en) | 2009-05-18 | 2018-04-04 | Sigmoid Pharma Limited | Composition comprising oil drops |
| US20110038910A1 (en) | 2009-08-11 | 2011-02-17 | Atrium Medical Corporation | Anti-infective antimicrobial-containing biomaterials |
| JP5911799B2 (ja) | 2009-08-12 | 2016-04-27 | シグモイド・ファーマ・リミテッドＳｉｇｍｏｉｄ Ｐｈａｒｍａ Ｌｉｍｉｔｅｄ | ポリマーマトリックスおよび油相を含んで成る免疫調節組成物 |
| WO2012009707A2 (en) | 2010-07-16 | 2012-01-19 | Atrium Medical Corporation | Composition and methods for altering the rate of hydrolysis of cured oil-based materials |
| GB201020032D0 (en) | 2010-11-25 | 2011-01-12 | Sigmoid Pharma Ltd | Composition |
| JO3337B1 (ar) | 2010-12-13 | 2019-03-13 | Debiopharm Sa | تركيبات صيدلية تشمل أليسبوريفير |
| US9867880B2 (en) | 2012-06-13 | 2018-01-16 | Atrium Medical Corporation | Cured oil-hydrogel biomaterial compositions for controlled drug delivery |
| GB201304662D0 (en) | 2013-03-14 | 2013-05-01 | Sigmoid Pharma Ltd | Compositions |
| EP3215127B1 (en) * | 2014-11-07 | 2020-10-28 | Sublimity Therapeutics Limited | Compositions comprising cyclosporin |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2907460A1 (de) * | 1978-03-07 | 1979-09-13 | Sandoz Ag | Neue resorbierbare galenische kompositionen |
| SE457693B (sv) * | 1986-07-01 | 1989-01-23 | Drilletten Ab | Komposition med reglerad frigoering vari ett biologiskt material aer loest eller dispergerat i en l2-fas |
| GB9113872D0 (en) * | 1991-06-27 | 1991-08-14 | Sandoz Ag | Improvements in or relating to organic compounds |
-
1995
- 1995-07-06 SE SE9502472A patent/SE504582C2/sv not_active IP Right Cessation
-
1996
- 1996-07-02 CA CA002226219A patent/CA2226219A1/en not_active Abandoned
- 1996-07-02 EP EP96923154A patent/EP0873133B1/en not_active Expired - Lifetime
- 1996-07-02 DE DE0873133T patent/DE873133T1/de active Pending
- 1996-07-02 WO PCT/SE1996/000893 patent/WO1997002042A1/en not_active Application Discontinuation
- 1996-07-02 JP JP9505078A patent/JPH11508592A/ja active Pending
- 1996-07-02 DE DE69619700T patent/DE69619700T2/de not_active Expired - Fee Related
- 1996-07-02 AT AT96923154T patent/ATE213951T1/de not_active IP Right Cessation
- 1996-07-02 ES ES96923154T patent/ES2123477T3/es not_active Expired - Lifetime
- 1996-07-02 BR BR9609332A patent/BR9609332A/pt not_active Application Discontinuation
- 1996-07-02 CZ CZ9819A patent/CZ1998A3/cs unknown
- 1996-07-02 AU AU63745/96A patent/AU6374596A/en not_active Abandoned
-
1998
- 1998-01-05 NO NO980032A patent/NO980032L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR9609332A (pt) | 1999-05-25 |
| AU6374596A (en) | 1997-02-05 |
| EP0873133B1 (en) | 2002-03-06 |
| ES2123477T3 (es) | 2002-08-01 |
| DE873133T1 (de) | 1999-05-06 |
| EP0873133A1 (en) | 1998-10-28 |
| WO1997002042A1 (en) | 1997-01-23 |
| SE9502472D0 (sv) | 1995-07-06 |
| NO980032L (no) | 1998-03-03 |
| ATE213951T1 (de) | 2002-03-15 |
| CZ1998A3 (cs) | 1998-06-17 |
| DE69619700D1 (de) | 2002-04-11 |
| CA2226219A1 (en) | 1997-01-23 |
| JPH11508592A (ja) | 1999-07-27 |
| NO980032D0 (no) | 1998-01-05 |
| DE69619700T2 (de) | 2002-10-24 |
| SE504582C2 (sv) | 1997-03-10 |
| SE9502472L (sv) | 1997-01-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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