NO974165L - Fremstilling av N-arylmetyl-aziridin-derivater, 1,4,7,10-tetraazacyklododekan-derivater fremstilt fra disse og N-arylmetyl-etanolamin-sulfonatestere som mellomprodukter - Google Patents

Fremstilling av N-arylmetyl-aziridin-derivater, 1,4,7,10-tetraazacyklododekan-derivater fremstilt fra disse og N-arylmetyl-etanolamin-sulfonatestere som mellomprodukter

Info

Publication number
NO974165L
NO974165L NO974165A NO974165A NO974165L NO 974165 L NO974165 L NO 974165L NO 974165 A NO974165 A NO 974165A NO 974165 A NO974165 A NO 974165A NO 974165 L NO974165 L NO 974165L
Authority
NO
Norway
Prior art keywords
arylmethyl
preparation
derivatives
intermediates
group
Prior art date
Application number
NO974165A
Other languages
English (en)
Norwegian (no)
Other versions
NO974165D0 (no
Inventor
Louis Messerle
Gandara Amarasinghe
Jere Fellmann
Martha Garrity
John Varadarajan
Janis Vasilevskis
Original Assignee
Nycomed Salutar Inc
Univ Iowa Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9504921.9A external-priority patent/GB9504921D0/en
Application filed by Nycomed Salutar Inc, Univ Iowa Res Found filed Critical Nycomed Salutar Inc
Publication of NO974165D0 publication Critical patent/NO974165D0/no
Publication of NO974165L publication Critical patent/NO974165L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/42—Separation; Purification; Stabilisation; Use of additives
    • C07C303/44—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D255/00—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D259/00—Heterocyclic compounds containing rings having more than four nitrogen atoms as the only ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NO974165A 1995-03-10 1997-09-09 Fremstilling av N-arylmetyl-aziridin-derivater, 1,4,7,10-tetraazacyklododekan-derivater fremstilt fra disse og N-arylmetyl-etanolamin-sulfonatestere som mellomprodukter NO974165L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9504921.9A GB9504921D0 (en) 1995-03-10 1995-03-10 Process
GBGB9526616.9A GB9526616D0 (en) 1995-03-10 1995-12-28 Process
PCT/GB1996/000552 WO1996028420A2 (fr) 1995-03-10 1996-03-08 Derives de la benzamidine, leur preparation et leur utilisation comme anticoagulants

Publications (2)

Publication Number Publication Date
NO974165D0 NO974165D0 (no) 1997-09-09
NO974165L true NO974165L (no) 1997-11-07

Family

ID=26306653

Family Applications (1)

Application Number Title Priority Date Filing Date
NO974165A NO974165L (no) 1995-03-10 1997-09-09 Fremstilling av N-arylmetyl-aziridin-derivater, 1,4,7,10-tetraazacyklododekan-derivater fremstilt fra disse og N-arylmetyl-etanolamin-sulfonatestere som mellomprodukter

Country Status (8)

Country Link
US (2) US6048979A (fr)
EP (1) EP0813523A2 (fr)
JP (1) JPH11511733A (fr)
CN (1) CN1181751A (fr)
AU (1) AU4949996A (fr)
CA (1) CA2214034A1 (fr)
NO (1) NO974165L (fr)
WO (1) WO1996028420A2 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5744616A (en) * 1996-02-26 1998-04-28 Schering Aktiengesellschaft Process for the production of 1,4,7,10-tetraazacyclododecane and its derivatives
DE19608307C1 (de) * 1996-02-26 1997-08-28 Schering Ag Verfahren zur Herstellung von 1,4,7,10-Tetraazacyclododecan und dessen Derivaten
JP3931392B2 (ja) 1997-08-25 2007-06-13 ソニー株式会社 立体画像用ビデオ信号生成装置、立体画像用ビデオ信号送出装置および立体画像用ビデオ信号受信装置
BRPI0512235A (pt) 2004-06-18 2008-02-19 Ambrx Inc polipeptìdeos ligadores de antìgenos e seus usos
CZ2005653A3 (cs) * 2005-10-17 2007-01-10 Azacycles S. R. O. Způsob přípravy 1,4,7,10-tetraazacyklododekanua jeho N-acylderivátů
EP2192922A4 (fr) 2007-09-17 2010-09-29 Univ California Anticorps monoclonaux humains internalisants ciblant des cellules du cancer de la prostate<i>in situ</i>
JP6196551B2 (ja) * 2010-04-12 2017-09-13 スパーナス ファーマシューティカルズ インコーポレイテッド ビロキサジン塩を製造する方法及びその新規な多形
CN103518135B (zh) 2011-03-11 2016-08-17 内布拉斯加大学董事委员会 冠状动脉疾病的生物标志物
US9315474B2 (en) 2012-10-02 2016-04-19 Liebel-Flarsheim Company Llc Process for the preparation of macrocyclic polyazacarboxylate ligands and chelates
CN104478931A (zh) * 2014-12-04 2015-04-01 内蒙古河西航天科技发展有限公司 三-1-(2-甲基氮丙啶)氧化膦的制备方法
WO2017095823A1 (fr) 2015-11-30 2017-06-08 The Regents Of The University Of California Administration de charge utile spécifique de tumeur et activation immunitaire au moyen d'un anticorps humain ciblant un antigène de surface de cellule tumorale très spécifique
CN108794417A (zh) * 2018-08-04 2018-11-13 许昌恒生制药有限公司 一种医疗诊断造影剂中间体的制备方法
CN116419747A (zh) 2020-08-07 2023-07-11 福蒂斯治疗公司 靶向cd46的免疫偶联物及其使用方法
CN112961161B (zh) * 2021-02-22 2022-05-13 南京邮电大学 一种用于磷酸二氢根离子特异性检测的荧光探针及检测方法
CN114591258A (zh) * 2022-01-19 2022-06-07 杭州盛弗泰新材料科技有限公司 一种轮环藤宁的制备和纯化方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE665790C (de) * 1935-05-12 1938-10-04 I G Farbenindustrie Akt Ges Verfahren zur Herstellung von Alkyleniminen
DE1160302B (de) * 1962-08-29 1963-12-27 Agfa Ag Photographisches Material
US4093615A (en) * 1971-09-13 1978-06-06 The Dow Chemical Company Cyclic oligomers of N-substituted aziridines
US3828023A (en) * 1971-09-13 1974-08-06 Dow Chemical Co Process for preparing cyclic oligomers of n-substituted aziridines
DE2740170C2 (de) * 1977-05-17 1982-02-04 Tabushi, Iwao, Kyoto Alkylsubstituierte cyclische Tetraalkylentetramine
DD160724B1 (de) * 1981-05-20 1987-01-14 Fotochem Werke Berlin Veb Fotografisches silberhalogenid-gelatine-material mit antifleckenmittel
US4885363A (en) * 1987-04-24 1989-12-05 E. R. Squibb & Sons, Inc. 1-substituted-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs

Also Published As

Publication number Publication date
CN1181751A (zh) 1998-05-13
NO974165D0 (no) 1997-09-09
JPH11511733A (ja) 1999-10-12
US6288224B1 (en) 2001-09-11
CA2214034A1 (fr) 1996-09-19
WO1996028420A3 (fr) 1996-12-12
AU4949996A (en) 1996-10-02
US6048979A (en) 2000-04-11
MX9706899A (es) 1997-11-29
WO1996028420A2 (fr) 1996-09-19
EP0813523A2 (fr) 1997-12-29

Similar Documents

Publication Publication Date Title
NO974165L (no) Fremstilling av N-arylmetyl-aziridin-derivater, 1,4,7,10-tetraazacyklododekan-derivater fremstilt fra disse og N-arylmetyl-etanolamin-sulfonatestere som mellomprodukter
AU7801291A (en) Tinctorial composition based on 5,6-dihydroxyindolines and method for dyeing keratinous fibres
ATE22889T1 (de) 8-chlor-1,5-benzothiazepinderivate, verfahren zur herstellung und pharmazeutische zusammensetzungen.
ATE14579T1 (de) Pharmazeutische heterocyclische verbindungen, verfahren zu ihrer herstellung und sie enthaltende zusammensetzungen.
NO924929L (no) Farmasoeytisk aktive benzoquinazolinforbindelser
AU7428191A (en) Chelating compounds and their use
ATE93863T1 (de) Enzym-hemmende aminosaeurederivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung.
SE8505716D0 (sv) Novel compounds and conjugates thereof
FI963440A (fi) Uudet aminohappojohdannaiset, näiden valmistusmenetelmä ja näitä yhdisteitä sisältävät farmaseuttiset seokset
ATE3149T1 (de) Isatinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
PT93126A (pt) Processo para a preparacao de eteres carboxialquilicos da 2-amino-7- -hidroxitetralina
NO923004L (no) 6-oxo-azepinoindolforbindelser, saavel som fremgangsmaater og mellomprodukter for fremstilling av disse, og legemidler inneholdende disse forbindelser
ATE115980T1 (de) Neue thyroninderivate.
AU4304596A (en) A process for the preparation of substituted 4-ethyl-piperidines and an intermediate for the preparation of same
ATE185550T1 (de) Verfahren zur herstellung von iodierten kontrastmitteln
ZA849159B (en) N-(methoxyphenacyl)-amine derivatives
HUT49326A (en) Process for producing sulfon derivatives as hydroxyalkilating agents
IL116646A (en) Antifungal fusacandins, process for their preparation, pharmaceutical compositions containing them and uses thereof
DE3764701D1 (de) N-((trimethoxy-2,4,6-benzoyl)-3-propyl)piperidin-derivate, verfahren zu ihrer herstellung und deren anwendung als heilmittel.
ATE72236T1 (de) Neue 9-substituierte carbacyclinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
ATE9896T1 (de) Substituierte 3-aryl-2-cycloalken-1-one, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
DK0429751T3 (da) Substituerede 3-aminosydnoniminer, fremgangsmåde til deres fremstilling og deres anvendelse

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application