NO972876L - Disubstituerte p-fluorbenzolsulfonamider - Google Patents

Disubstituerte p-fluorbenzolsulfonamider

Info

Publication number
NO972876L
NO972876L NO972876A NO972876A NO972876L NO 972876 L NO972876 L NO 972876L NO 972876 A NO972876 A NO 972876A NO 972876 A NO972876 A NO 972876A NO 972876 L NO972876 L NO 972876L
Authority
NO
Norway
Prior art keywords
hydrogen atom
hydroxy groups
group
cooh
hydrogen
Prior art date
Application number
NO972876A
Other languages
English (en)
Other versions
NO972876D0 (no
Inventor
Ulrich Niedballa
Johannes Platzek
Bernd Raduechel
Thomas Frenzel
Hans Bauer
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO972876L publication Critical patent/NO972876L/no
Publication of NO972876D0 publication Critical patent/NO972876D0/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Disubstituerte p-fluorbenzen- sulfonamider innebioldende en CFj-gruppe med den generelle formel I (I) Z NHS02(W-C0)¿-A hvori Z betegner en CFj-gruppe eller et hydrogenatom, Y betegner en Ci-Cj,-alkylgruppe som kan være substituert med 1 til 4 hydroksy- grupper eller avbrutt av 1 til 2 oksy- genatomer, en (CHj),,COOH- eller (CHj)^CONR'R^-gruppe hvor o betegner tallet 0 eller 1 og R^ og R^ uavhengig av hverandre betegner hydrogen og en C'-Cj-alkylgruppe som eventuelt er substituert med 1 til 4 hydroksy- grupper, X betegner et hydrogenatom eller har betydningen angitt for Y, W betegner en Co-Cj-alkylengruppe som kan være substituert med 1 til 4 hydroksygrupper eller avbrutt av 1 til 2 oksygenatomer, n betegner tallet 0 eller 1, A betegner restene -OH, 0R\ -CH3, CHjCFj, -NH-CHj-COOH, -NH-CR'( CF3)-COOH hvor R^ betegner et hydrogenatom eller en rettkjedet eller forgrenet Ci-Cj,- alkylgruppe som eventuelt er substi- tuert med 1 til 2 hydroksygrupper, med det forbehold at X betegner et hydrogenatom når Z betegner en CF3- gruppe, at X har en av betydningene angitt for Y når Z betegner et hydro- genatom, og at om ønskelig syregruppene i molekylet foreligger i form av deres amider eller i form av salter med organiske eller uorganiske base.
NO972876A 1994-12-22 1997-06-20 Disubstituerte p-fluorbenzolsulfonamider NO972876D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4447389A DE4447389A1 (de) 1994-12-22 1994-12-22 Disubstituierte p-Fluorbenzolsulfonamide
PCT/EP1995/004825 WO1996019447A1 (de) 1994-12-22 1995-12-08 Disubstituierte p-fluorbenzosulfonamide und ihre verwendung bei der nmr-diagnostik

Publications (2)

Publication Number Publication Date
NO972876L true NO972876L (no) 1997-06-20
NO972876D0 NO972876D0 (no) 1997-06-20

Family

ID=6537589

Family Applications (1)

Application Number Title Priority Date Filing Date
NO972876A NO972876D0 (no) 1994-12-22 1997-06-20 Disubstituerte p-fluorbenzolsulfonamider

Country Status (7)

Country Link
US (1) US5686492A (no)
EP (1) EP0799197A1 (no)
JP (1) JPH11500414A (no)
CA (1) CA2208341A1 (no)
DE (1) DE4447389A1 (no)
NO (1) NO972876D0 (no)
WO (1) WO1996019447A1 (no)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2215849A1 (en) * 1997-09-11 1999-03-11 Christophe Michot New solvent and electrolytic composition with high conductivity and wide stability range

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3920444A (en) * 1970-12-21 1975-11-18 Minnesota Mining & Mfg Method comprising the use of N-substituted perfluoroalkyanesulfonamides as herbicidal and plant growth modifying agents, and composition
DE3834704A1 (de) * 1988-10-07 1990-06-07 Schering Ag Fluorsubstituierte benzolderivate
HUT63827A (en) * 1990-02-07 1993-10-28 Nippon Shinyaku Co Ltd Process for producing sulfonanilide derivatives and pharmaceutical compositions comprising same
DE4008179A1 (de) * 1990-03-12 1991-09-19 Schering Ag Fluorbenzolsulfonamide

Also Published As

Publication number Publication date
DE4447389A1 (de) 1996-06-27
JPH11500414A (ja) 1999-01-12
WO1996019447A1 (de) 1996-06-27
CA2208341A1 (en) 1996-06-27
EP0799197A1 (de) 1997-10-08
US5686492A (en) 1997-11-11
NO972876D0 (no) 1997-06-20

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