NO971070L - Antivirus-nukleosid-analoger inneholdende en substituert benzimidazol-base knyttet til en karbocyklisk ring - Google Patents
Antivirus-nukleosid-analoger inneholdende en substituert benzimidazol-base knyttet til en karbocyklisk ringInfo
- Publication number
- NO971070L NO971070L NO971070A NO971070A NO971070L NO 971070 L NO971070 L NO 971070L NO 971070 A NO971070 A NO 971070A NO 971070 A NO971070 A NO 971070A NO 971070 L NO971070 L NO 971070L
- Authority
- NO
- Norway
- Prior art keywords
- dichloro
- benzimidazol
- hydroxymethyl
- cyclopentanediol
- compound
- Prior art date
Links
- 125000002837 carbocyclic group Chemical group 0.000 title description 3
- 239000002777 nucleoside Substances 0.000 title description 3
- 230000002155 anti-virotic effect Effects 0.000 title description 2
- 150000003833 nucleoside derivatives Chemical class 0.000 title description 2
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- FZORJBVDVIFUMJ-FOLSVITISA-N (1s,2r,3s,5s)-3-[5,6-dichloro-2-(propan-2-ylamino)benzimidazol-1-yl]-5-(hydroxymethyl)cyclopentane-1,2-diol Chemical compound CC(C)NC1=NC2=CC(Cl)=C(Cl)C=C2N1[C@H]1C[C@@H](CO)[C@H](O)[C@@H]1O FZORJBVDVIFUMJ-FOLSVITISA-N 0.000 claims description 5
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
Landscapes
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- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/304,006 US5534535A (en) | 1992-03-09 | 1994-09-09 | Therapeutic nucleosides |
| PCT/US1995/011366 WO1996007646A1 (en) | 1994-09-09 | 1995-09-11 | Antiviral nucleoside analogues containing a substituted benzimidazole base attached to a carbocyclic ring |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO971070D0 NO971070D0 (no) | 1997-03-07 |
| NO971070L true NO971070L (no) | 1997-05-07 |
Family
ID=23174626
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO971070A NO971070L (no) | 1994-09-09 | 1997-03-07 | Antivirus-nukleosid-analoger inneholdende en substituert benzimidazol-base knyttet til en karbocyklisk ring |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0779885A1 (cs) |
| JP (1) | JPH10505092A (cs) |
| CN (1) | CN1164855A (cs) |
| AP (1) | AP741A (cs) |
| AU (1) | AU3692895A (cs) |
| BR (1) | BR9508826A (cs) |
| CA (1) | CA2199502A1 (cs) |
| CZ (1) | CZ71297A3 (cs) |
| FI (1) | FI970959A7 (cs) |
| HU (1) | HUT77440A (cs) |
| IS (1) | IS4436A (cs) |
| NO (1) | NO971070L (cs) |
| NZ (1) | NZ294095A (cs) |
| OA (1) | OA10601A (cs) |
| PL (1) | PL319440A1 (cs) |
| SK (1) | SK29197A3 (cs) |
| WO (1) | WO1996007646A1 (cs) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5912356A (en) * | 1995-09-11 | 1999-06-15 | Glaxo Wellcome Inc. | Antiviral nucleoside analogues containing a substituted benzimidazole base attached to a carbocyclic ring |
| GB9600142D0 (en) * | 1996-01-05 | 1996-03-06 | Wellcome Found | Chemical compounds |
| CA2280761A1 (en) | 1997-02-13 | 1998-08-20 | Stanley Dawes Chamberlain | Benzimidazole derivatives |
| WO1999006424A1 (en) | 1997-07-30 | 1999-02-11 | The Regents Of The University Of Michigan | Lyxofuranosyl benzimidazoles as antiviral agents |
| HUP0202263A3 (en) | 1999-12-27 | 2003-02-28 | Japan Tobacco Inc | Benzimidazole, indole and imidazo-pyridine derivatives and pharmaceutical compositions containing them |
| US6770666B2 (en) | 1999-12-27 | 2004-08-03 | Japan Tobacco Inc. | Fused-ring compounds and use thereof as drugs |
| GB0008939D0 (en) | 2000-04-11 | 2000-05-31 | Glaxo Group Ltd | Process for preparing substituted benzimidazole compounds |
| AR035543A1 (es) * | 2001-06-26 | 2004-06-16 | Japan Tobacco Inc | Agente terapeutico para la hepatitis c que comprende un compuesto de anillo condensado, compuesto de anillo condensado, composicion farmaceutica que lo comprende, compuestos de benzimidazol, tiazol y bifenilo utiles como intermediarios para producir dichos compuestos, uso del compuesto de anillo con |
| CN1834090B (zh) * | 2005-03-18 | 2011-06-29 | 中国科学院上海药物研究所 | 苯并咪唑类化合物、其制备方法以及用途 |
| EP2178880B1 (en) | 2007-08-02 | 2017-10-04 | Millennium Pharmaceuticals, Inc. | Process for the synthesis of e1 activating enzyme inhibitors |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9205071D0 (en) * | 1992-03-09 | 1992-04-22 | Wellcome Found | Therapeutic nucleosides |
-
1995
- 1995-09-11 AU AU36928/95A patent/AU3692895A/en not_active Abandoned
- 1995-09-11 EP EP95934402A patent/EP0779885A1/en not_active Withdrawn
- 1995-09-11 BR BR9508826A patent/BR9508826A/pt not_active Application Discontinuation
- 1995-09-11 PL PL95319440A patent/PL319440A1/xx unknown
- 1995-09-11 JP JP8509679A patent/JPH10505092A/ja not_active Ceased
- 1995-09-11 CN CN95196148A patent/CN1164855A/zh active Pending
- 1995-09-11 CA CA002199502A patent/CA2199502A1/en not_active Abandoned
- 1995-09-11 HU HU9702310A patent/HUT77440A/hu unknown
- 1995-09-11 AP APAP/P/1997/000940A patent/AP741A/en active
- 1995-09-11 CZ CZ97712A patent/CZ71297A3/cs unknown
- 1995-09-11 NZ NZ294095A patent/NZ294095A/en unknown
- 1995-09-11 SK SK291-97A patent/SK29197A3/sk unknown
- 1995-09-11 WO PCT/US1995/011366 patent/WO1996007646A1/en not_active Ceased
-
1997
- 1997-03-06 FI FI970959A patent/FI970959A7/fi unknown
- 1997-03-07 IS IS4436A patent/IS4436A/is unknown
- 1997-03-07 OA OA60973A patent/OA10601A/en unknown
- 1997-03-07 NO NO971070A patent/NO971070L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR9508826A (pt) | 1997-09-30 |
| OA10601A (en) | 2002-09-03 |
| WO1996007646A1 (en) | 1996-03-14 |
| AP9700940A0 (en) | 1997-04-30 |
| EP0779885A1 (en) | 1997-06-25 |
| PL319440A1 (en) | 1997-08-04 |
| NO971070D0 (no) | 1997-03-07 |
| FI970959A7 (fi) | 1997-05-06 |
| IS4436A (is) | 1997-03-07 |
| JPH10505092A (ja) | 1998-05-19 |
| CN1164855A (zh) | 1997-11-12 |
| AP741A (en) | 1999-04-26 |
| NZ294095A (en) | 1998-08-26 |
| FI970959A0 (fi) | 1997-03-06 |
| SK29197A3 (en) | 1997-10-08 |
| CZ71297A3 (en) | 1997-08-13 |
| HUT77440A (hu) | 1998-04-28 |
| CA2199502A1 (en) | 1996-03-14 |
| AU3692895A (en) | 1996-03-27 |
| MX9701789A (es) | 1997-10-31 |
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