NO970356L - PTH eller PTHrP antagonister - Google Patents
PTH eller PTHrP antagonisterInfo
- Publication number
- NO970356L NO970356L NO970356A NO970356A NO970356L NO 970356 L NO970356 L NO 970356L NO 970356 A NO970356 A NO 970356A NO 970356 A NO970356 A NO 970356A NO 970356 L NO970356 L NO 970356L
- Authority
- NO
- Norway
- Prior art keywords
- pth
- amino acid
- pthrp
- tryptophan
- aromatic
- Prior art date
Links
- 108700020797 Parathyroid Hormone-Related Proteins 0.000 title abstract 2
- 102000043299 Parathyroid hormone-related Human genes 0.000 title abstract 2
- 239000005557 antagonist Substances 0.000 title 1
- 125000000539 amino acid group Chemical group 0.000 abstract 4
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 abstract 2
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000001072 heteroaryl group Chemical group 0.000 abstract 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
- 101150071808 PTHLH gene Proteins 0.000 abstract 1
- 102000006461 Parathyroid Hormone Receptors Human genes 0.000 abstract 1
- 108010058828 Parathyroid Hormone Receptors Proteins 0.000 abstract 1
- 230000003042 antagnostic effect Effects 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- 239000011575 calcium Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9415254A GB9415254D0 (en) | 1994-07-28 | 1994-07-28 | Organic compounds |
GB9415255A GB9415255D0 (en) | 1994-07-28 | 1994-07-28 | Organic compounds |
PCT/EP1995/002993 WO1996003437A1 (en) | 1994-07-28 | 1995-07-27 | PTH OR PTHrP ANTAGONISTS |
Publications (2)
Publication Number | Publication Date |
---|---|
NO970356D0 NO970356D0 (no) | 1997-01-28 |
NO970356L true NO970356L (no) | 1997-01-28 |
Family
ID=26305357
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO970356A NO970356L (no) | 1994-07-28 | 1997-01-28 | PTH eller PTHrP antagonister |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0773958A1 (hu) |
JP (1) | JPH10502091A (hu) |
AU (1) | AU3167095A (hu) |
BR (1) | BR9508433A (hu) |
CA (1) | CA2192787A1 (hu) |
CO (1) | CO4410206A1 (hu) |
CZ (1) | CZ23397A3 (hu) |
FI (1) | FI970168A0 (hu) |
HU (1) | HUT77979A (hu) |
IL (1) | IL114736A0 (hu) |
NO (1) | NO970356L (hu) |
PL (1) | PL318017A1 (hu) |
SK (1) | SK12097A3 (hu) |
TR (1) | TR199500915A2 (hu) |
WO (1) | WO1996003437A1 (hu) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW505654B (en) * | 1996-07-30 | 2002-10-11 | Hoffmann La Roche | Synthesis of analogs of PTH and PTHrP |
ATE304020T1 (de) * | 1996-07-31 | 2005-09-15 | Gen Hospital Corp | Parathyroidhormon-verwandthe peptidanaloge |
US6903194B1 (en) | 1996-09-26 | 2005-06-07 | Chungai Seiyaku Kabushiki Kaisha | Antibody against human parathormone related peptides |
BR9808786A (pt) | 1997-05-14 | 2000-07-11 | Rhone Poulenc Rorer Pharma | Composto peptìdio cìclico ou um seu sal ou pró-medicamento farmaceuticamente aceitáveis, composição farmacêutica, e, processos para tratar doenças associadas com a regulagem do cálcio em um paciente e para tratar a osteopenia ou a osteoporose em um mamìfero hospedeiro |
US20020165363A1 (en) | 1997-05-15 | 2002-11-07 | Koh Sato | Cachexia remedy |
AU5708500A (en) * | 1999-07-02 | 2001-01-22 | Chugai Seiyaku Kabushiki Kaisha | Remedies for diseases caused by pth or pthrp |
TWI255718B (en) | 1999-07-02 | 2006-06-01 | Chugai Pharmaceutical Co Ltd | Ameliorative agent for low vasopressin concentration |
AU5849700A (en) * | 1999-07-06 | 2001-01-22 | Chugai Seiyaku Kabushiki Kaisha | Remedies for drug-resistant hypercalcemia |
DE60024118T2 (de) * | 1999-09-20 | 2006-07-27 | Eli Lilly And Co., Indianapolis | Verwendung einer parathyroidhormone zur reduktion des krebsrisikos |
WO2001054725A1 (fr) * | 2000-01-25 | 2001-08-02 | Chugai Seiyaku Kabushiki Kaisha | Remèdes et agents prophylactiques pour maladies dentaires |
CA2401357A1 (en) * | 2000-02-28 | 2001-09-07 | Chugai Seiyaku Kabushiki Kaisha | Tissue degradation inhibitor agent |
WO2001082968A1 (fr) | 2000-04-28 | 2001-11-08 | Chugai Seiyaku Kabushiki Kaisha | Inhibiteurs de proliferation cellulaire |
WO2002013865A1 (fr) * | 2000-08-16 | 2002-02-21 | Chugai Seiyaku Kabushiki Kaisha | Agents destines a soulager les symptomes provoques par des maladies articulaires |
US8568737B2 (en) | 2007-08-01 | 2013-10-29 | The General Hospital Corporation | Screening methods using G-protein coupled receptors and related compositions |
JP5941040B2 (ja) | 2010-05-13 | 2016-06-29 | ザ ジェネラル ホスピタル コーポレイション | 副甲状腺ホルモン類似体およびその使用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2040264A1 (en) * | 1990-04-12 | 1991-10-13 | Tatsuhiko Kanmera | Parathyroid hormone antagonists |
EP0539491A1 (en) * | 1990-07-13 | 1993-05-05 | The Regents Of The University Of California | PARATHYROID HORMONE ANALOGUES MODIFIED AT POSITIONS 3, 6 or 9 |
AU672790B2 (en) * | 1992-07-15 | 1996-10-17 | Novartis Ag | Variants of parathyroid hormone and its fragments |
-
1995
- 1995-07-21 CO CO95032396A patent/CO4410206A1/es unknown
- 1995-07-26 IL IL11473695A patent/IL114736A0/xx unknown
- 1995-07-27 WO PCT/EP1995/002993 patent/WO1996003437A1/en not_active Application Discontinuation
- 1995-07-27 AU AU31670/95A patent/AU3167095A/en not_active Abandoned
- 1995-07-27 HU HU9700245A patent/HUT77979A/hu unknown
- 1995-07-27 CA CA002192787A patent/CA2192787A1/en not_active Abandoned
- 1995-07-27 SK SK120-97A patent/SK12097A3/sk unknown
- 1995-07-27 EP EP95927739A patent/EP0773958A1/en not_active Withdrawn
- 1995-07-27 PL PL95318017A patent/PL318017A1/xx unknown
- 1995-07-27 BR BR9508433A patent/BR9508433A/pt not_active Application Discontinuation
- 1995-07-27 CZ CZ97233A patent/CZ23397A3/cs unknown
- 1995-07-27 JP JP8505489A patent/JPH10502091A/ja active Pending
- 1995-07-28 TR TR95/00915A patent/TR199500915A2/xx unknown
-
1997
- 1997-01-15 FI FI970168A patent/FI970168A0/fi not_active Application Discontinuation
- 1997-01-28 NO NO970356A patent/NO970356L/no unknown
Also Published As
Publication number | Publication date |
---|---|
EP0773958A1 (en) | 1997-05-21 |
NO970356D0 (no) | 1997-01-28 |
PL318017A1 (en) | 1997-05-12 |
TR199500915A2 (tr) | 1996-06-21 |
IL114736A0 (en) | 1995-11-27 |
CO4410206A1 (es) | 1997-01-09 |
FI970168A (fi) | 1997-01-15 |
BR9508433A (pt) | 1998-07-14 |
JPH10502091A (ja) | 1998-02-24 |
SK12097A3 (en) | 1997-08-06 |
HUT77979A (hu) | 1999-01-28 |
MX9700446A (es) | 1998-06-28 |
CZ23397A3 (en) | 1997-07-16 |
CA2192787A1 (en) | 1996-02-08 |
FI970168A0 (fi) | 1997-01-15 |
AU3167095A (en) | 1996-02-22 |
WO1996003437A1 (en) | 1996-02-08 |
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