NO965097L - Nye elastaseinhibitorer - Google Patents

Nye elastaseinhibitorer

Info

Publication number
NO965097L
NO965097L NO965097A NO965097A NO965097L NO 965097 L NO965097 L NO 965097L NO 965097 A NO965097 A NO 965097A NO 965097 A NO965097 A NO 965097A NO 965097 L NO965097 L NO 965097L
Authority
NO
Norway
Prior art keywords
inhibitors
elastase inhibitors
elastase
compounds
new
Prior art date
Application number
NO965097A
Other languages
English (en)
Norwegian (no)
Other versions
NO965097D0 (no
Inventor
Jr William Arthur Metz
Steven Lee Gallion
Joseph Paul Burkhart
Michael Richard Angelastro
Norton Paul Peet
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of NO965097D0 publication Critical patent/NO965097D0/no
Publication of NO965097L publication Critical patent/NO965097L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO965097A 1994-06-02 1996-11-29 Nye elastaseinhibitorer NO965097L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25279994A 1994-06-02 1994-06-02
PCT/US1995/005618 WO1995033763A1 (en) 1994-06-02 1995-05-05 Novel elastase inhibitors

Publications (2)

Publication Number Publication Date
NO965097D0 NO965097D0 (no) 1996-11-29
NO965097L true NO965097L (no) 1997-01-31

Family

ID=22957608

Family Applications (1)

Application Number Title Priority Date Filing Date
NO965097A NO965097L (no) 1994-06-02 1996-11-29 Nye elastaseinhibitorer

Country Status (20)

Country Link
EP (1) EP0804465B1 (da)
JP (1) JP3623799B2 (da)
KR (1) KR100347285B1 (da)
CN (1) CN1149877A (da)
AT (1) ATE246708T1 (da)
AU (1) AU689589B2 (da)
CA (1) CA2189527C (da)
DE (1) DE69531459T2 (da)
DK (1) DK0804465T3 (da)
ES (1) ES2199992T3 (da)
FI (1) FI964781A7 (da)
HU (1) HU221197B1 (da)
IL (1) IL113940A (da)
NO (1) NO965097L (da)
NZ (1) NZ285565A (da)
PT (1) PT804465E (da)
SI (1) SI0804465T1 (da)
TW (1) TW403762B (da)
WO (1) WO1995033763A1 (da)
ZA (1) ZA954430B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4221059B2 (ja) * 1994-06-02 2009-02-12 アベンティス・インコーポレイテッド エラスターゼインヒビターのプロドラッグとしてのアシル化エノール誘導体
ES2137509T3 (es) * 1994-06-02 1999-12-16 Merrell Pharma Inc Perfluoroalquilcetonas, inhibidoras de elastasa y procedimientos para su preparacion.
US5948886A (en) * 1996-11-20 1999-09-07 Hoechst Marion Roussel, Inc. Acylated enol derivatives of α-ketoesters and α-ketoamides
US6172044B1 (en) 1995-12-01 2001-01-09 Aventis Pharmaceuticals Inc. Acylated enol derivative of α-ketoesters and α-ketoamides
US6767991B1 (en) 1997-08-11 2004-07-27 Boehringer Ingelheim (Canada) Ltd. Hepatitis C inhibitor peptides
NZ544076A (en) 2003-05-21 2009-04-30 Boehringer Ingelheim Int Hepatitis C inhibitor compounds
CA2573346C (en) 2004-07-20 2011-09-20 Boehringer Ingelheim International Gmbh Hepatitis c inhibitor peptide analogs
UY29016A1 (es) 2004-07-20 2006-02-24 Boehringer Ingelheim Int Analogos de dipeptidos inhibidores de la hepatitis c
MX2008014839A (es) 2006-05-23 2008-12-05 Irm Llc Compuestos y composiciones en la forma de inhibidores de proteasa de activacion mediante canal.
EA016327B1 (ru) * 2007-02-09 2012-04-30 Айрм Ллк Соединения и композиции в качестве ингибиторов протеазы, активирующей каналы
EP4031138A1 (en) 2019-09-17 2022-07-27 Mereo Biopharma 4 Limited Alvelestat for use in the treatment of graft rejection, bronchiolitis obliterans syndrome and graft versus host disease
DK4106757T3 (da) 2020-04-16 2023-10-23 Mereo Biopharma 4 Ltd Fremgangsmåder der involverer neutrofil elastase-inhibitor alvelestat til behandling af luftvejssygdom medieret af alpha-1-antitrypsin-mangel
JP2024540952A (ja) 2021-10-20 2024-11-06 メレオ バイオファーマ ４ リミテッド 線維化の治療における使用のための好中球エラスターゼ阻害剤

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8600263D0 (en) * 1985-01-22 1986-02-12 Ici America Inc Peptide derivatives
ATE71934T1 (de) * 1985-06-07 1992-02-15 Ici America Inc Selektionierte difluorverbindungen.
CA2021660A1 (en) * 1989-07-26 1991-01-27 Philippe Bey Peptidase inhibitors
JPH06504547A (ja) * 1990-12-28 1994-05-26 ジョージア・テック・リサーチ・コーポレーション ペプチドケトアミド、ケト酸およびケトエステル
AU655831B2 (en) * 1991-08-22 1995-01-12 Merrell Pharmaceuticals Inc. Novel orally-active elastase inhibitors

Also Published As

Publication number Publication date
DK0804465T3 (da) 2003-11-24
CA2189527C (en) 2000-12-19
DE69531459T2 (de) 2004-06-24
AU2470995A (en) 1996-01-04
NO965097D0 (no) 1996-11-29
CA2189527A1 (en) 1995-12-14
IL113940A0 (en) 1995-08-31
KR100347285B1 (ko) 2003-01-15
EP0804465A1 (en) 1997-11-05
CN1149877A (zh) 1997-05-14
TW403762B (en) 2000-09-01
DE69531459D1 (de) 2003-09-11
HU221197B1 (en) 2002-08-28
IL113940A (en) 1999-12-31
JP3623799B2 (ja) 2005-02-23
WO1995033763A1 (en) 1995-12-14
EP0804465B1 (en) 2003-08-06
FI964781L (fi) 1997-01-29
JPH10500992A (ja) 1998-01-27
SI0804465T1 (en) 2003-12-31
HUT76926A (hu) 1998-01-28
ZA954430B (en) 1996-02-13
MX9606030A (es) 1998-05-31
FI964781A0 (fi) 1996-11-29
HU9603312D0 (en) 1997-01-28
FI964781A7 (fi) 1997-01-29
AU689589B2 (en) 1998-04-02
ATE246708T1 (de) 2003-08-15
PT804465E (pt) 2003-12-31
NZ285565A (en) 1998-08-26
ES2199992T3 (es) 2004-03-01

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