NO963374L - Substituerte 4H-pyraner - Google Patents

Substituerte 4H-pyraner

Info

Publication number
NO963374L
NO963374L NO963374A NO963374A NO963374L NO 963374 L NO963374 L NO 963374L NO 963374 A NO963374 A NO 963374A NO 963374 A NO963374 A NO 963374A NO 963374 L NO963374 L NO 963374L
Authority
NO
Norway
Prior art keywords
carbon atoms
substituted
pyrans
branched alkyl
straight chain
Prior art date
Application number
NO963374A
Other languages
English (en)
Other versions
NO963374D0 (no
Inventor
Klaus Urbahns
Hans-Georg Heine
Bodo Junge
Frank Mauler
Thomas Glaser
Reilinde Wittka
Jean-Marie-Viktor De Vry
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of NO963374D0 publication Critical patent/NO963374D0/no
Publication of NO963374L publication Critical patent/NO963374L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/32Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Abstract

Det blir beskrevet substituerte 4H-pyraner med den generelle formel (I) hvor A står for cykloalkyl med 3 til 6 karbonatomer eller for rettkjedet eller forgrenet alkyl med opptil 8 karbonatomer, eller står for aryl med 6 til 10 karbonatomer eller for pyridyl, som eventuelt er substituert, r1 og r2 er like eller forskjellige og står for hydrogen, amino eller rettkjedet eller forgrenet alkyl, alkoksy eller alkylamino, alle med opptil 8 karbonatomer, r3 og R4 er like eller forskjellige og står for rettkjedet eller forgrenet alkyl eller acyl med alltid opptil 6 karbonatomer, og deres salter. Det blir dessuten beskrevet en fremgangsmåte for fremstilling av substituerte 4H-pyraner, samt deres anvendelse som virkestoff i legemidler, spesielt for behandling av sykdommer i det sentrale nervesystem.
NO963374A 1995-08-14 1996-08-13 Substituerte 4H-pyraner NO963374L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19529858A DE19529858A1 (de) 1995-08-14 1995-08-14 Substituierte 4H-Pyrane

Publications (2)

Publication Number Publication Date
NO963374D0 NO963374D0 (no) 1996-08-13
NO963374L true NO963374L (no) 1997-02-17

Family

ID=7769442

Family Applications (1)

Application Number Title Priority Date Filing Date
NO963374A NO963374L (no) 1995-08-14 1996-08-13 Substituerte 4H-pyraner

Country Status (25)

Country Link
US (1) US5760073A (no)
EP (1) EP0758648B1 (no)
JP (1) JPH0959271A (no)
KR (1) KR970010758A (no)
CN (1) CN1147512A (no)
AT (1) ATE190611T1 (no)
AU (1) AU708956B2 (no)
CA (1) CA2183048A1 (no)
CZ (1) CZ239496A3 (no)
DE (2) DE19529858A1 (no)
DK (1) DK0758648T3 (no)
EE (1) EE9600114A (no)
ES (1) ES2145355T3 (no)
GR (1) GR3033357T3 (no)
HU (1) HUP9602220A3 (no)
IL (1) IL119054A (no)
MX (1) MX9603342A (no)
NO (1) NO963374L (no)
NZ (1) NZ299145A (no)
PL (1) PL315652A1 (no)
PT (1) PT758648E (no)
RU (1) RU2164915C2 (no)
SI (1) SI0758648T1 (no)
SK (1) SK105596A3 (no)
ZA (1) ZA966832B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2329739T3 (es) * 1997-04-07 2009-11-30 Georgetown University Analogos de cocaina.
US6221550B1 (en) 2000-03-31 2001-04-24 Nexpress Solutions Llc 4H-pyran charge control agents for electrostatographic toners and developers
WO2009006580A1 (en) * 2007-07-05 2009-01-08 Cv Therapeutics, Inc. Optionally condensed dihydropyridine, dihydropyrimidine and dihydropyrane derivatives acting as late sodium channel blockers
US20090012103A1 (en) 2007-07-05 2009-01-08 Matthew Abelman Substituted heterocyclic compounds
JP5120070B2 (ja) * 2008-05-29 2013-01-16 三浦工業株式会社 水処理装置

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3208628A1 (de) * 1982-03-10 1983-09-22 Bayer Ag, 5090 Leverkusen Neue verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
DK0758648T3 (da) 2000-07-24
RU2164915C2 (ru) 2001-04-10
ZA966832B (en) 1997-02-20
NO963374D0 (no) 1996-08-13
JPH0959271A (ja) 1997-03-04
CN1147512A (zh) 1997-04-16
SI0758648T1 (en) 2000-06-30
CZ239496A3 (en) 1997-03-12
AU6193196A (en) 1997-02-20
DE19529858A1 (de) 1997-02-20
AU708956B2 (en) 1999-08-19
GR3033357T3 (en) 2000-09-29
HUP9602220A3 (en) 1998-04-28
SK105596A3 (en) 1997-03-05
ATE190611T1 (de) 2000-04-15
ES2145355T3 (es) 2000-07-01
PT758648E (pt) 2000-08-31
HU9602220D0 (en) 1996-10-28
US5760073A (en) 1998-06-02
EP0758648A1 (de) 1997-02-19
EP0758648B1 (de) 2000-03-15
DE59604649D1 (de) 2000-04-20
EE9600114A (et) 1997-02-17
MX9603342A (es) 1997-03-29
KR970010758A (ko) 1997-03-27
HUP9602220A2 (en) 1997-05-28
CA2183048A1 (en) 1997-02-15
IL119054A (en) 2000-10-31
NZ299145A (en) 1998-03-25
IL119054A0 (en) 1996-11-14
PL315652A1 (en) 1997-02-17

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