NO963371D0 - Hematopoeseprotein samt materialer og fremgangsmåter for fremstilling av det - Google Patents

Hematopoeseprotein samt materialer og fremgangsmåter for fremstilling av det

Info

Publication number
NO963371D0
NO963371D0 NO963371A NO963371A NO963371D0 NO 963371 D0 NO963371 D0 NO 963371D0 NO 963371 A NO963371 A NO 963371A NO 963371 A NO963371 A NO 963371A NO 963371 D0 NO963371 D0 NO 963371D0
Authority
NO
Norway
Prior art keywords
hematopoiesis
protein
making
materials
methods
Prior art date
Application number
NO963371A
Other languages
English (en)
Other versions
NO963371L (no
Inventor
Richard D Holly
Si Lok
Donald Cameron Foster
Frederick S Hagen
Kenneth Kaushansky
Joseph L Kuijper
Catherine E Lofton-Day
Pieter J Oort
Steven K Burkhead
Original Assignee
Zymogenetics Inc
Univ Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc, Univ Washington filed Critical Zymogenetics Inc
Publication of NO963371D0 publication Critical patent/NO963371D0/no
Publication of NO963371L publication Critical patent/NO963371L/no

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047Cells of the immune system
    • G01N33/5055Cells of the immune system involving macrophages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/196Thrombopoietin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0642Granulocytes, e.g. basopils, eosinophils, neutrophils, mast cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082Supracellular entities, e.g. tissue, organisms
    • G01N33/5088Supracellular entities, e.g. tissue, organisms of vertebrates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5094Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/145Thrombopoietin [TPO]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/22Colony stimulating factors (G-CSF, GM-CSF)
NO963371A 1994-02-14 1996-08-13 Hematopoietisk protein samt materialer og fremgangsmåter for fremstilling av det NO963371L (no)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US19602594A 1994-02-14 1994-02-14
US20319794A 1994-02-25 1994-02-25
US21520394A 1994-03-21 1994-03-21
US25249194A 1994-06-01 1994-06-01
PCT/US1994/008806 WO1995021920A1 (en) 1994-02-14 1994-08-05 Hematopoietic protein and materials and methods for making it

Publications (2)

Publication Number Publication Date
NO963371D0 true NO963371D0 (no) 1996-08-13
NO963371L NO963371L (no) 1996-10-11

Family

ID=27498094

Family Applications (1)

Application Number Title Priority Date Filing Date
NO963371A NO963371L (no) 1994-02-14 1996-08-13 Hematopoietisk protein samt materialer og fremgangsmåter for fremstilling av det

Country Status (17)

Country Link
US (1) US5989537A (no)
EP (1) EP0745125A1 (no)
JP (1) JPH09508797A (no)
KR (1) KR100289201B1 (no)
CN (1) CN1148408A (no)
AU (1) AU691828B2 (no)
BG (1) BG63508B1 (no)
BR (1) BR9408534A (no)
CA (1) CA2183266A1 (no)
CZ (1) CZ221496A3 (no)
FI (1) FI963185A (no)
HU (1) HUT75359A (no)
NO (1) NO963371L (no)
NZ (1) NZ271230A (no)
PL (1) PL178384B1 (no)
SK (1) SK100896A3 (no)
WO (1) WO1995021920A1 (no)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RO115788B1 (ro) * 1994-03-31 2000-06-30 Amgen Inc. Polipeptidă mgdf, derivat de polipeptidă mgdf, polipeptidă mgdf mono-pegilată şi procedee de obţinere a acestora
US5795569A (en) * 1994-03-31 1998-08-18 Amgen Inc. Mono-pegylated proteins that stimulate megakaryocyte growth and differentiation
TW387940B (en) * 1995-01-17 2000-04-21 Kirin Brewery Anti-tpo monodonal antibody
CA2212006A1 (en) 1995-02-03 1996-08-08 G.D. Searle & Co. Novel c-mpl ligands
US5696250A (en) * 1995-02-15 1997-12-09 Amgen Inc. DNA encoding megakaryocyte growth and development factor analogs
US5989538A (en) * 1995-02-15 1999-11-23 Amgen Inc. Mpl ligand analogs
TW434021B (en) * 1995-03-15 2001-05-16 Kirin Brewery Methods for preventing adsorption of thrombopoietin (TPO), and stable TPO-containing compositions
TW434020B (en) * 1995-03-15 2001-05-16 Kirin Brewery Methods for preventing adsorption of thrombopoietin (TPO), and stable top-containing compositions
US5869451A (en) * 1995-06-07 1999-02-09 Glaxo Group Limited Peptides and compounds that bind to a receptor
US6251864B1 (en) 1995-06-07 2001-06-26 Glaxo Group Limited Peptides and compounds that bind to a receptor
EP1961760A3 (en) 1995-06-07 2008-09-03 Glaxo Group Limited Peptides and compounds that bind to a thrombopoietin receptor
TW497972B (en) * 1995-06-08 2002-08-11 Kirin Brewery Stable thrombopoietin (TPO)-containing lyophilized compositions
US6060052A (en) * 1995-10-30 2000-05-09 Systemix, Inc. Methods for use of Mpl ligands with primitive human hematopoietic stem cells
US5792850A (en) * 1996-05-23 1998-08-11 Zymogenetics, Inc. Hematopoietic cytokine receptor
US7091311B2 (en) 1996-06-07 2006-08-15 Smithkline Beecham Corporation Peptides and compounds that bind to a receptor
US6884419B1 (en) * 1996-12-23 2005-04-26 Kyowa Hakko Kogyo, Co., Ltd. hG-CSF fusion polypeptide having c-mpl activity, DNA coding for same and methods of treating anemia using same
US20030228666A1 (en) 1998-06-30 2003-12-11 Daewoong Pharmaceutical Co., Ltd. Novel human thrombopoietin mutein
MEP42108A (en) 1998-10-23 2011-02-10 Kiren Amgen Inc Dimeric thrombopoietin peptide mimetics binding to mp1 receptor and having thrombopoietic activity
US6660843B1 (en) 1998-10-23 2003-12-09 Amgen Inc. Modified peptides as therapeutic agents
JP4739526B2 (ja) 1998-12-07 2011-08-03 ザイモジェネティクス, インコーポレイテッド 成長因子相同体zvegf3
US6776984B1 (en) 1999-08-20 2004-08-17 George R. Schwartz Induced regeneration and repair of damaged neurons and nerve axon myelin
CY2010012I2 (el) 2000-05-25 2020-05-29 Novartis Ag Μιμητικα θρομβοποιητινης
EP1294888B1 (en) 2000-06-30 2007-04-25 ZymoGenetics, Inc. Interferon-like protein zcyto21
US7332474B2 (en) 2001-10-11 2008-02-19 Amgen Inc. Peptides and related compounds having thrombopoietic activity
EP1336846A1 (en) * 2002-02-13 2003-08-20 Procorde GmbH Method for generating recombinant human platelets for identifying therapeutic target proteins
WO2003080806A2 (en) * 2002-03-18 2003-10-02 National Jewish Medical And Research Center Method for production of neutrophils and uses therefor
US20030191056A1 (en) 2002-04-04 2003-10-09 Kenneth Walker Use of transthyretin peptide/protein fusions to increase the serum half-life of pharmacologically active peptides/proteins
DE10227611A1 (de) * 2002-06-20 2004-01-15 Bionethos Holding Gmbh Verfahren und Vorrichtung zur Vermehrung und Differenzierung von Zellen in Anwesenheit von Wachstumsfaktoren und einer biologischen Matrix oder Trägerstruktur
US20040028661A1 (en) * 2002-08-07 2004-02-12 Bartelmez Stephen H. Expansion of cells using thrombopoietin and anti-transforming growth factor-beta
WO2004014938A2 (en) * 2002-08-09 2004-02-19 Xencor Thrombopoiesis-stimulating proteins having reduced immunogenicity
PT1542714E (pt) 2002-09-18 2014-06-23 Janssen Pharmaceuticals Inc Métodos para aumentar a produção de células estaminais plaquetárias e hematopoiéticas
US20090143453A1 (en) * 2003-04-29 2009-06-04 Connie Erickson-Miller Methods for treating degenerative diseases/injuries
US20100004302A1 (en) * 2003-04-29 2010-01-07 Connie Erickson-Miller Methods for Treating Degenerative Diseases/Injuries
US20090048318A1 (en) * 2003-04-29 2009-02-19 Connie Erickson-Miller Methods for treating degenerative diseases/injuries
WO2004096154A2 (en) 2003-04-29 2004-11-11 Smithkline Beecham Corporation Methods for treating degenerative diseases/injuries
US20090298179A1 (en) * 2003-04-29 2009-12-03 Connie Erickson-Miller Methods For Treating Degenerative Diseases/Injuries
ATE388963T1 (de) 2003-08-07 2008-03-15 Zymogenetics Inc Homogene herstellungen von il-29
US7723295B2 (en) 2003-08-28 2010-05-25 Ortho-Mcneil Pharmaceutical, Inc. Peptides and compounds that bind to a receptor
PL1675606T3 (pl) 2003-08-28 2017-08-31 Janssen Pharmaceuticals, Inc. Peptydy i związki, które wiążą się z receptorami trombopoetyny
EP1682074B1 (en) * 2003-10-24 2012-02-08 Nora Therapeutics, Inc. Compositions and methods for healthy pregnancy
US20090226397A1 (en) * 2003-10-24 2009-09-10 Nora Therapeutics, Inc. Compositions and methods for reducing the likelihood of implantation failure or miscarriage in recipients of artificial insemination
US8338373B2 (en) * 2003-10-24 2012-12-25 Nora Therapeutics, Inc. Method for reducing the risk of spontaneous abortion in a human female subject
PL1699915T3 (pl) 2003-12-30 2010-11-30 Augustinus Bader Zastosowanie erytropoetyny do regeneracji tkanki wątrobowej
EP1773400A2 (en) 2004-07-08 2007-04-18 Amgen Inc. Therapeutic peptides
CA2585343C (en) 2004-10-25 2016-06-21 Cellerant Therapeutics, Inc. Methods of expanding myeloid cell populations and uses thereof
US8008453B2 (en) 2005-08-12 2011-08-30 Amgen Inc. Modified Fc molecules
WO2007102946A2 (en) 2006-01-23 2007-09-13 Amgen Inc. Crystalline polypeptides
US7981425B2 (en) 2006-06-19 2011-07-19 Amgen Inc. Thrombopoietic compounds
AU2008262490B2 (en) 2007-05-22 2011-11-17 Amgen Inc. Compositions and methods for producing bioactive fusion proteins
KR101040396B1 (ko) 2009-01-20 2011-06-09 한올바이오파마주식회사 변형된 인간 트롬보포이에틴 폴리펩타이드 절편 및 그의 제조방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5154921A (en) * 1990-07-13 1992-10-13 Dana-Farber Cancer Institute, Inc. Promotion of maturation of hematopoietic progenitor cells
US5571686A (en) * 1994-04-14 1996-11-05 Massachusetts Institute Of Technology Method of using megapoietin for prolonging the survival & viability of platlets

Also Published As

Publication number Publication date
PL315914A1 (en) 1996-12-09
CN1148408A (zh) 1997-04-23
KR100289201B1 (ko) 2001-05-02
US5989537A (en) 1999-11-23
HU9602224D0 (en) 1996-10-28
AU7481094A (en) 1995-08-29
PL178384B1 (pl) 2000-04-28
SK100896A3 (en) 1997-10-08
FI963185A0 (fi) 1996-08-14
BG63508B1 (bg) 2002-03-29
JPH09508797A (ja) 1997-09-09
AU691828B2 (en) 1998-05-28
BG100771A (en) 1997-08-29
CA2183266A1 (en) 1995-08-17
NO963371L (no) 1996-10-11
FI963185A (fi) 1996-08-14
WO1995021920A1 (en) 1995-08-17
HUT75359A (en) 1997-05-28
BR9408534A (pt) 1997-08-05
CZ221496A3 (en) 1997-07-16
NZ271230A (en) 1998-03-25
EP0745125A1 (en) 1996-12-04

Similar Documents

Publication Publication Date Title
NO963371D0 (no) Hematopoeseprotein samt materialer og fremgangsmåter for fremstilling av det
IS1810B (is) Úðablöndur úr peptíðum og próteinum
NO20071415L (no) OB-fusjonsproteinpreparater og fremgangsmater
NO20000700D0 (no) Interleukin-18-proteiner samt fremstilling og anvendelse derav
DE69616813D1 (de) Halographisches aufzeichnungsmaterial und verfahren
FI935485A (fi) PEG-hydratsoni- ja PEG-oksiimisidoksen muodostavat reagenssit ja niiden proteiinijohdannaiset
BR9407089A (pt) Moega e método
BR9506832A (pt) N-pirazolilanilinas e n-pirazolilaminopiridinas
DE69527170T2 (de) Navigationsvorrichtung und -verfahren
KR960008810A (ko) 편집 방법 및 편집 제어 기기
DE69528180D1 (de) Modifiziertes molkeprotein
DK132892D0 (da) Proteiner
DE69409379D1 (de) Ultraschallabtastgerät und -verfahren
NO971505D0 (no) Trofinin og trofininhjelperproteiner
FI972763A0 (fi) Mutanttiproteiineja
DE69425770D1 (de) Direktes Aufzeichnungsverfahren und direkte Aufzeichnungsvorrichtung
NO960766D0 (no) Nytt protein og fremgangsmåte for fremstilling av dette
TR199701666A3 (tr) Sismanliga karsi proteinler
KR960010685A (ko) 펩티드 및 그 용도
DE69614491T2 (de) 5HT1Dalpha und 5HT2A Ligande
BR9507133A (pt) N-aril e n-alquilsulfonilaminais
DK120792D0 (da) Protein
SE9602287D0 (sv) Novel protein and methods for its use
KR960005550U (ko) 볼트
DE69519715D1 (de) PRLTS-Proteine und die dafür kodierende DNA

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application