NO962244L - Fremgangsmåte for forhöyelse av stabiliteten av liposom-suspensjoner inneholdende hydrofile aktive materialer - Google Patents

Fremgangsmåte for forhöyelse av stabiliteten av liposom-suspensjoner inneholdende hydrofile aktive materialer

Info

Publication number
NO962244L
NO962244L NO962244A NO962244A NO962244L NO 962244 L NO962244 L NO 962244L NO 962244 A NO962244 A NO 962244A NO 962244 A NO962244 A NO 962244A NO 962244 L NO962244 L NO 962244L
Authority
NO
Norway
Prior art keywords
stability
increasing
active materials
containing hydrophilic
suspensions containing
Prior art date
Application number
NO962244A
Other languages
English (en)
Other versions
NO962244D0 (no
Inventor
Andreas Sachse
Georg Rossling
Jens Leike
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO962244D0 publication Critical patent/NO962244D0/no
Publication of NO962244L publication Critical patent/NO962244L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions
    • A61K49/1812—Suspensions, emulsions, colloids, dispersions liposomes, polymersomes, e.g. immunoliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0461—Dispersions, colloids, emulsions or suspensions
    • A61K49/0466—Liposomes, lipoprotein vesicles, e.g. HDL or LDL lipoproteins, phospholipidic or polymeric micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Dispersion Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO962244A 1993-12-02 1996-05-31 Fremgangsmåte for forhöyelse av stabiliteten av liposom-suspensjoner inneholdende hydrofile aktive materialer NO962244L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4341472A DE4341472A1 (de) 1993-12-02 1993-12-02 Verfahren zur Erhöhung der Stabilität von hydrophile Wirkstoffe enthaltenden Liposomensuspensionen
PCT/EP1994/003964 WO1995015153A1 (de) 1993-12-02 1994-11-30 Verfahren zur erhöhung der stabilität von hydrophile wirkstoffe enthaltenden liposomensuspensionen

Publications (2)

Publication Number Publication Date
NO962244D0 NO962244D0 (no) 1996-05-31
NO962244L true NO962244L (no) 1996-05-31

Family

ID=6504253

Family Applications (1)

Application Number Title Priority Date Filing Date
NO962244A NO962244L (no) 1993-12-02 1996-05-31 Fremgangsmåte for forhöyelse av stabiliteten av liposom-suspensjoner inneholdende hydrofile aktive materialer

Country Status (9)

Country Link
US (1) US6475515B2 (no)
EP (1) EP0731689A1 (no)
JP (1) JPH09505821A (no)
AU (1) AU1241695A (no)
CA (1) CA2177973A1 (no)
DE (1) DE4341472A1 (no)
HU (1) HUT75465A (no)
NO (1) NO962244L (no)
WO (1) WO1995015153A1 (no)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9416149D0 (en) * 1994-08-10 1994-09-28 Univ Strathclyde Vesicle formulation
DE4430592A1 (de) * 1994-08-20 1996-02-22 Max Delbrueck Centrum Liposomale Zubereitung, ihre Herstellung und ihre Verwendung
DE19606326A1 (de) * 1995-02-09 1996-08-22 Schering Ag Kontrastmittelhaltige Liposomenformulierung sowie deren Verwendung für die In-vivo-Diagnostik, insbesondere für die Darstellung des Intravasalraumes
DE19529922A1 (de) * 1995-08-01 1997-02-06 Schering Ag Verwendung von liposomalen Zubereitungen in der indirekten MRT-Lymphographie
JP2003513030A (ja) * 1999-11-05 2003-04-08 シード・キャピタル・インヴェストメンツ−２・（エスシーアイ−２）・ベスローテン・フエンノートシャップ 低い水溶性および脂肪親和性を示す物質のカプセル化方法、およびこの方法により得られる製剤
US8357351B2 (en) * 2004-04-21 2013-01-22 Ananth Annapragada Nano-scale contrast agents and methods of use
US7713517B2 (en) * 2004-04-21 2010-05-11 Marval Biosciences, Inc. Compositions and methods for enhancing contrast in imaging
US20050255154A1 (en) 2004-05-11 2005-11-17 Lena Pereswetoff-Morath Method and composition for treating rhinitis
WO2006009022A1 (ja) * 2004-07-21 2006-01-26 Konica Minolta Medical & Graphic, Inc. リポソーム含有ｘ線造影剤およびその製造方法
WO2006100692A2 (en) * 2005-03-21 2006-09-28 Lifecare Innovations Pvt. Ltd. A novel inter and intra multilamellar vesicular composition.
JP5846711B2 (ja) * 2005-06-09 2016-01-20 メダ アーベー 炎症性疾患の治療のための方法及び組成物
WO2007026151A1 (en) * 2005-09-01 2007-03-08 Biolipox Ab Antihistamine- and corticosteroid- containing liposome composition and its use for the manufacture of a medicament for treating rhinitis and related disorders
CA2708028A1 (en) * 2007-12-05 2009-06-11 Marval Biosciences, Inc. Nano-scale contrast agents and methods of use
AU2009257279A1 (en) * 2008-06-13 2009-12-17 Marval Biosciences, Inc. Imaging of atherosclerotic plaques using liposomal imaging agents
EP2773325B1 (en) * 2011-11-04 2018-09-19 Enceladus Pharmaceuticals B.V. Liposomal corticosteroids for treatment of inflammatory disorders in humans
KR102310786B1 (ko) * 2013-02-01 2021-10-12 존원 파마, 인코포레이티드 리포좀 내로 난수용성 약물의 원격 부하
WO2015156904A1 (en) * 2014-04-08 2015-10-15 Aradigm Corporation Liposomes that form drug nanocrystals after freeze-thaw
US20160120806A1 (en) * 2014-04-08 2016-05-05 Aradigm Corporation Nanocrystals formed in a microenvironment
CN107072944B (zh) 2014-04-08 2021-11-02 阿拉迪姆公司 具有抗非结核分枝杆菌活性的脂质体环丙沙星制剂
US10004759B2 (en) 2014-08-04 2018-06-26 Zoneone Pharma, Inc. Remote loading of sparingly water-soluble drugs into lipid vesicles
WO2018035476A1 (en) * 2016-08-18 2018-02-22 Troy Bremer Delivery of urea to cells of the macula and retina using liposome constructs
JP2023549170A (ja) * 2020-11-03 2023-11-22 ヴェセロン， インコーポレイテッド 担体を使用する治療薬の標的化送達のための組成物および方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2416008A1 (fr) * 1978-02-02 1979-08-31 Oreal Lyophilisats de liposomes
US4897355A (en) * 1985-01-07 1990-01-30 Syntex (U.S.A.) Inc. N[ω,(ω-1)-dialkyloxy]- and N-[ω,(ω-1)-dialkenyloxy]-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor
US4857319A (en) * 1985-01-11 1989-08-15 The Regents Of The University Of California Method for preserving liposomes
GB8727590D0 (en) * 1987-11-25 1987-12-31 Fisons Plc Formulation
EP0437479B1 (en) * 1988-10-05 1994-06-22 Vestar, Inc. Method of making liposomes with improved stability during drying
IL94718A (en) * 1989-07-05 1994-10-21 Schering Ag Non-ionic carboxamide contrast agent and method of preparation
DE3934656A1 (de) * 1989-10-13 1991-04-18 Schering Ag Verfahren zur herstellung von waessrigen dispersionen
WO1993020802A1 (en) * 1992-04-09 1993-10-28 Northwestern University Acoustically reflective liposomes and methods to make and use the same

Also Published As

Publication number Publication date
HUT75465A (en) 1997-05-28
DE4341472A1 (de) 1995-06-08
US20020102293A1 (en) 2002-08-01
EP0731689A1 (de) 1996-09-18
JPH09505821A (ja) 1997-06-10
US6475515B2 (en) 2002-11-05
CA2177973A1 (en) 1995-06-08
NO962244D0 (no) 1996-05-31
HU9601476D0 (en) 1996-07-29
AU1241695A (en) 1995-06-19
WO1995015153A1 (de) 1995-06-08

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