NO961814D0 - Substituerte di- og tripetidinhibitorer for protein:farnesyl-transferase - Google Patents

Substituerte di- og tripetidinhibitorer for protein:farnesyl-transferase

Info

Publication number
NO961814D0
NO961814D0 NO961814A NO961814A NO961814D0 NO 961814 D0 NO961814 D0 NO 961814D0 NO 961814 A NO961814 A NO 961814A NO 961814 A NO961814 A NO 961814A NO 961814 D0 NO961814 D0 NO 961814D0
Authority
NO
Norway
Prior art keywords
tripetide
inhibitors
protein
substituted
farnesyl transferase
Prior art date
Application number
NO961814A
Other languages
English (en)
Other versions
NO961814L (no
Inventor
Gary Louis Bolton
Mark Wallace Creswell
John Cooke Hodges
Michael William Wilson
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of NO961814D0 publication Critical patent/NO961814D0/no
Publication of NO961814L publication Critical patent/NO961814L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06147—Dipeptides with the first amino acid being heterocyclic and His-amino acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO961814A 1993-11-05 1996-05-03 Substituerte di- og tripetidinhibitorer for protein:farnesyl-transferase NO961814L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14873593A 1993-11-05 1993-11-05
US30330194A 1994-09-13 1994-09-13
PCT/US1994/011553 WO1995012612A1 (en) 1993-11-05 1994-10-12 Substituted di- and tripeptide inhibitors of protein:farnesyl transferase

Publications (2)

Publication Number Publication Date
NO961814D0 true NO961814D0 (no) 1996-05-03
NO961814L NO961814L (no) 1996-05-06

Family

ID=26846110

Family Applications (1)

Application Number Title Priority Date Filing Date
NO961814A NO961814L (no) 1993-11-05 1996-05-03 Substituerte di- og tripetidinhibitorer for protein:farnesyl-transferase

Country Status (10)

Country Link
EP (1) EP0730605A1 (no)
JP (1) JP3597863B2 (no)
KR (1) KR100362338B1 (no)
AU (1) AU681454B2 (no)
CA (1) CA2170766A1 (no)
FI (1) FI961819A (no)
HU (1) HUT75308A (no)
NO (1) NO961814L (no)
NZ (1) NZ275691A (no)
WO (1) WO1995012612A1 (no)

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US5523456A (en) * 1994-09-29 1996-06-04 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5652257A (en) * 1994-09-29 1997-07-29 Merck & Co., Inc. Heterocycle-containing inhibitors of farnesyl-protein transferase
JPH10508005A (ja) * 1994-09-29 1998-08-04 メルク エンド カンパニー インコーポレーテッド チオールを有しないファルネシル−タンパク質トランスフェラーゼ阻害剤
US5972984A (en) * 1995-06-06 1999-10-26 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5756528A (en) * 1995-06-06 1998-05-26 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
FR2736641B1 (fr) * 1995-07-10 1997-08-22 Rhone Poulenc Rorer Sa Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
US5968965A (en) * 1996-01-30 1999-10-19 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5981562A (en) * 1996-01-30 1999-11-09 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US6011029A (en) * 1996-02-26 2000-01-04 Bristol-Myers Squibb Company Inhibitors of farnesyl protein transferase
US6300501B1 (en) 1996-05-22 2001-10-09 Warner-Lambert Company Histidine-(N-benzyl glycinamide) inhibitors of protein farnesyl transferase
SK161098A3 (en) * 1996-05-22 2000-06-12 Warner Lambert Co Inhibitors of protein farnesyl transferase
BR9713744A (pt) 1996-12-17 2000-03-21 Warner Lambert Co Inibidores de cicloalquia da proteìna farnesil transferase
FR2757855B1 (fr) * 1996-12-30 1999-01-29 Rhone Poulenc Rorer Sa Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
US6013662A (en) 1996-12-30 2000-01-11 Rhone-Poulenc Rorer S.A. Farnesyl transferase inhibitors, their preparation, the pharmaceutical compositions which contain them and their use in the preparation of medicaments
US6124465A (en) * 1997-11-25 2000-09-26 Rhone-Poulenc S.A. Farnesyl transferase inhibitors, their preparation, the pharmaceutical compositions which contain them and their use in the preparation of medicaments
US6423689B1 (en) 1997-12-22 2002-07-23 Warner-Lambert Company Peptidyl calcium channel blockers
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Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2072033A1 (en) * 1991-06-28 1992-12-29 Jackson B. Gibbs Non-substrate inhibitors of farnesyl protein transferase

Also Published As

Publication number Publication date
JPH09504547A (ja) 1997-05-06
WO1995012612A1 (en) 1995-05-11
FI961819A0 (fi) 1996-04-29
CA2170766A1 (en) 1995-05-11
AU7976094A (en) 1995-05-23
JP3597863B2 (ja) 2004-12-08
AU681454B2 (en) 1997-08-28
EP0730605A1 (en) 1996-09-11
HUT75308A (en) 1997-05-28
HU9601193D0 (en) 1996-07-29
KR100362338B1 (ko) 2003-04-08
NZ275691A (en) 1998-03-25
FI961819A (fi) 1996-04-29
NO961814L (no) 1996-05-06

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