NO961130L - Nye tiofenforbindelser, fremgangsmåte ved deres fremstilling og farmasöytiske sammensetninger inneholdende dem - Google Patents

Nye tiofenforbindelser, fremgangsmåte ved deres fremstilling og farmasöytiske sammensetninger inneholdende dem

Info

Publication number
NO961130L
NO961130L NO961130A NO961130A NO961130L NO 961130 L NO961130 L NO 961130L NO 961130 A NO961130 A NO 961130A NO 961130 A NO961130 A NO 961130A NO 961130 L NO961130 L NO 961130L
Authority
NO
Norway
Prior art keywords
alkyl
processes
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
NO961130A
Other languages
English (en)
Other versions
NO961130D0 (no
Inventor
Michel Wierzbicki
Marie-Francoise Boussard
Jacqueline Bonnet
Massimo Sabatini
Philippe Pastoureau
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of NO961130D0 publication Critical patent/NO961130D0/no
Publication of NO961130L publication Critical patent/NO961130L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)

Abstract

Nye tiofenforbindelser med formel: hvor - hver av X og Y, som er like eller forskjellige, representerer et hydrogen- eller halogenatom, et alkyl- eller alkoksyradikal som hver har fra l til 5 karbon- atomer i en rett eller forgrenet kjede, eller et dial- kylaminoradikal, hvori hver alkylgruppe inneholder fra l til 5 karbonatomer i en rett eller forgrenet kjede; n representerer et heltall fra 2 til 5; m representerer O, l eller 2; R representerer et hydrogenatom eller et alkylradikal med l til 5 karbonatomer i et rett eller forgrenet kjede; og R' representerer et akylradikal med fra l til 5 karbonatomer i et rett eller forgrenet kjede; eller R og R' danner sammen med nitrogenatomene som de er bundet til, et pentagonalt eller heksagonalt heterocyklisk radikal som eventuelt inneholder et oksy- genatom eller et andre nitrogenatom, hvilket heterocyk- liske radikal er usubstituert eller substituert med et alkylradikal som har fra l til 5 karbonatomer i en rett eller forgrenet kjede eller med et arylalkylradikal hvor alkylgruppen inneholder fra l til 5 karbonatomer i en rett eller forgrenet kjede, og arylgruppen (som for- trinnsvis er fenyl) er usubstituert eller substituert med en eller flere identiske eller forskjellige substi- tuenter valgt fra halogenatomer og alkyl- og alkoksy- radikaler som hver har fra l til 5 karbonatomer i en rett eller forgrenet kjede, og hvor de forekommer, de tilsvarende enantiomerer, og deres fysiologisk aksepta- ble salter. Produktene ifølge oppfinnelsen kan anvendes terapeutisk spesielt ved behandling av enhver patologi som innebæ- rer ben-hyper-resorpsjon.
NO961130A 1995-03-21 1996-03-20 Nye tiofenforbindelser, fremgangsmåte ved deres fremstilling og farmasöytiske sammensetninger inneholdende dem NO961130L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9503246A FR2732021B1 (fr) 1995-03-21 1995-03-21 Nouveaux composes du thiophene, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
NO961130D0 NO961130D0 (no) 1996-03-20
NO961130L true NO961130L (no) 1996-09-23

Family

ID=9477224

Family Applications (1)

Application Number Title Priority Date Filing Date
NO961130A NO961130L (no) 1995-03-21 1996-03-20 Nye tiofenforbindelser, fremgangsmåte ved deres fremstilling og farmasöytiske sammensetninger inneholdende dem

Country Status (16)

Country Link
US (1) US5670535A (no)
EP (1) EP0733627B1 (no)
JP (1) JPH08269044A (no)
CN (1) CN1058715C (no)
AT (1) ATE194140T1 (no)
AU (1) AU698308B2 (no)
CA (1) CA2172114C (no)
DE (1) DE69608983T2 (no)
DK (1) DK0733627T3 (no)
ES (1) ES2150081T3 (no)
FR (1) FR2732021B1 (no)
GR (1) GR3033991T3 (no)
NO (1) NO961130L (no)
NZ (1) NZ286225A (no)
PT (1) PT733627E (no)
ZA (1) ZA962258B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3476203B2 (ja) 1997-02-24 2003-12-10 ザイモジュネティックス インコーポレイテッド カルシトニン擬似体
US6268367B1 (en) 1998-02-23 2001-07-31 Zymogenetics, Inc. Piperazine derivatives for treating bone deficit conditions
EP1366015A4 (en) * 2001-03-01 2008-03-26 Tech Resources Pty Ltd BENZENE-1 2-DIOL MANNICH BASES, LIGANDS, POLYMERS, AND SELECTIVE METAL ION REMOVAL METHOD

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3560525A (en) * 1967-10-13 1971-02-02 Parke Davis & Co 5-phenyl-2-furanacetic acids,5-phenyl-2-thiopheneacetic acids,and their derivatives
US3960893A (en) * 1968-04-16 1976-06-01 Imperial Chemical Industries Limited Phenyl-thienyl-alkanoic acid derivatives and phenyl-furyl-alkanoic acid derivatives
DE3407510A1 (de) * 1984-03-01 1985-09-05 A. Nattermann & Cie GmbH, 5000 Köln (omega)-aryl-alkylthienylalk(a,e)nsaeuren und ihre derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
FR2655043B1 (fr) * 1989-11-24 1992-02-07 Adir Nouveaux derives du thiophene, leur procede de preparation et les compositions pharmaceutiques les renfermant.

Also Published As

Publication number Publication date
DK0733627T3 (da) 2000-10-23
DE69608983D1 (de) 2000-08-03
EP0733627B1 (fr) 2000-06-28
AU4816496A (en) 1996-10-03
CA2172114C (fr) 2002-04-30
FR2732021B1 (fr) 1997-04-25
EP0733627A1 (fr) 1996-09-25
ES2150081T3 (es) 2000-11-16
US5670535A (en) 1997-09-23
CN1058715C (zh) 2000-11-22
JPH08269044A (ja) 1996-10-15
FR2732021A1 (fr) 1996-09-27
PT733627E (pt) 2000-10-31
ATE194140T1 (de) 2000-07-15
AU698308B2 (en) 1998-10-29
CA2172114A1 (fr) 1996-09-22
NO961130D0 (no) 1996-03-20
CN1141920A (zh) 1997-02-05
NZ286225A (en) 1997-06-24
ZA962258B (en) 1996-09-26
GR3033991T3 (en) 2000-11-30
DE69608983T2 (de) 2001-04-26

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application