NO954878L - Pyrrolderivater - Google Patents

Pyrrolderivater

Info

Publication number
NO954878L
NO954878L NO954878A NO954878A NO954878L NO 954878 L NO954878 L NO 954878L NO 954878 A NO954878 A NO 954878A NO 954878 A NO954878 A NO 954878A NO 954878 L NO954878 L NO 954878L
Authority
NO
Norway
Prior art keywords
compounds
pyrrole
inflammation
pain
useful
Prior art date
Application number
NO954878A
Other languages
English (en)
Norwegian (no)
Other versions
NO954878D0 (no
Inventor
Jim W Barnett
James P Dunn
Denis J Kertesz
Aaron B Miller
Jr David John Morgans
Chakk S Ramesha
C Elliott Sigal
Eric Brian Sjogren
David B Smith
Francisco X Talamas
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO954878D0 publication Critical patent/NO954878D0/no
Publication of NO954878L publication Critical patent/NO954878L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
NO954878A 1994-12-01 1995-11-30 Pyrrolderivater NO954878L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/347,915 US5622948A (en) 1994-12-01 1994-12-01 Pyrrole pyridazine and pyridazinone anti-inflammatory agents

Publications (2)

Publication Number Publication Date
NO954878D0 NO954878D0 (no) 1995-11-30
NO954878L true NO954878L (no) 1996-06-03

Family

ID=23365840

Family Applications (1)

Application Number Title Priority Date Filing Date
NO954878A NO954878L (no) 1994-12-01 1995-11-30 Pyrrolderivater

Country Status (19)

Country Link
US (1) US5622948A (fr)
EP (1) EP0714895A1 (fr)
JP (1) JPH08208639A (fr)
KR (1) KR960022506A (fr)
CN (1) CN1066726C (fr)
AR (1) AR001771A1 (fr)
AU (1) AU3906295A (fr)
BR (1) BR9505610A (fr)
CA (1) CA2163490A1 (fr)
CO (1) CO4650183A1 (fr)
CZ (1) CZ316995A3 (fr)
FI (1) FI955783A (fr)
HU (1) HUT75117A (fr)
IL (1) IL116139A0 (fr)
MA (1) MA23735A1 (fr)
NO (1) NO954878L (fr)
PL (1) PL311536A1 (fr)
TR (1) TR199501528A1 (fr)
ZA (1) ZA9510027B (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622948A (en) * 1994-12-01 1997-04-22 Syntex (U.S.A.) Inc. Pyrrole pyridazine and pyridazinone anti-inflammatory agents
US6231888B1 (en) 1996-01-18 2001-05-15 Perio Products Ltd. Local delivery of non steroidal anti inflammatory drugs (NSAIDS) to the colon as a treatment for colonic polyps
CA2205757C (fr) * 1996-05-30 2006-01-24 F. Hoffmann-La Roche Ag Derives de pyridazinone et leur utilisation comme inhibiteurs de la protasglandine g/h synthase i et ii(cox i et ii)
JP3142581B2 (ja) * 1996-05-30 2001-03-07 エフ・ホフマン―ラ ロシュ アーゲー 新規ピロール誘導体
CZ300847B6 (cs) * 1997-08-22 2009-08-26 Abbott Laboratories Arylpyridazinony jako inhibitory biosyntézy prostaglandin endoperoxid H synthasy, jejich použití a farmaceutická kompozice s jejich obsahem
BR9812127A (pt) * 1997-08-22 2000-07-18 Abbott Lab Arilpiridazinonas como inibidores da biossìntese de prostagleina endoperóxido h sintase
US6307047B1 (en) 1997-08-22 2001-10-23 Abbott Laboratories Prostaglandin endoperoxide H synthase biosynthesis inhibitors
US6525053B1 (en) 1997-08-22 2003-02-25 Abbott Laboratories Prostaglandin endoperoxide H synthase biosynthesis inhibitors
AU749505B2 (en) * 1997-10-27 2002-06-27 Dr. Reddy's Laboratories Limited Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them
US6531152B1 (en) 1998-09-30 2003-03-11 Dexcel Pharma Technologies Ltd. Immediate release gastrointestinal drug delivery system
CN1279026C (zh) * 1998-10-27 2006-10-11 艾博特公司 前列腺素内过氧化物h合酶生物合成抑制剂
US6632451B2 (en) 1999-06-04 2003-10-14 Dexcel Pharma Technologies Ltd. Delayed total release two pulse gastrointestinal drug delivery system
CA2450073C (fr) 2001-07-25 2017-08-29 Biomarin Pharmaceutical Inc. Compositions et procedes de modulation du transport a travers la barriere hematho-encephalique
CA2492022A1 (fr) * 2002-07-11 2004-01-22 Merck & Co., Inc. Traitement de la douleur neuropathique au moyen de composes 6h-pyrrolo[3,4-d]pyridazine
EP2392258B1 (fr) 2005-04-28 2014-10-08 Proteus Digital Health, Inc. Systeme pharma-informatique
GB0610680D0 (en) 2006-05-31 2006-07-12 Istituto Di Ricerche D Biolog Therapeutic compounds
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료
ES2524787T3 (es) * 2007-11-15 2014-12-12 Msd Italia S.R.L. Derivados de piridazinona como inhibidores de PARP
EP2398500B1 (fr) 2009-02-20 2019-03-13 2-BBB Medicines B.V. Sustème d'administration de médicament à base de glutathionne
MY163048A (en) 2009-05-06 2017-08-15 Laboratory Skin Care Inc Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
EP2527335B1 (fr) 2011-04-26 2013-09-18 King Saud University Dérivés de la triazole comme anti-inflammatoires
KR102233456B1 (ko) 2017-05-31 2021-03-29 주식회사 대웅제약 4-메톡시피롤 유도체의 중간체 제조 방법
KR102233455B1 (ko) 2017-06-21 2021-03-29 주식회사 대웅제약 4-메톡시피롤 유도체의 중간체 제조 방법
WO2022159980A1 (fr) * 2021-01-25 2022-07-28 Athos Therapeutics, Inc. Composés pharmaceutiques et leurs procédés de fabrication et méthodes d'utilisation

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2316942A (en) * 1937-12-27 1943-04-20 Schlumberger Well Surv Corp Apparatus for measuring temperatures in boreholes
US3586681A (en) * 1967-11-02 1971-06-22 Sandoz Ag 1,4,5,6-tetrahydropyridazines
US3726978A (en) * 1967-11-02 1973-04-10 Sandoz Ag Tetrahydropyridazines and pyridazinones as anti-inflammatory agents
US3752826A (en) * 1970-01-26 1973-08-14 Mcneilab Inc Aroyl substituted pyrroles
US4048191A (en) * 1975-06-27 1977-09-13 Mcneil Laboratories, Incorporated Halo-substituted 1-loweralkyl-5-aroylpyrrole-2-acetic acid compounds
JPS539788A (en) * 1976-07-14 1978-01-28 Syntex Inc 55aloyll1*22dihydroo3hh pyroro *1*22a* pyroll11 carboxylic acid derivative
US4089969A (en) * 1976-07-14 1978-05-16 Syntex (U.S.A.) Inc. 5-Aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives and process for the production thereof
US4247551A (en) * 1979-09-17 1981-01-27 Gruppo Lepetit S.P.A. N-Pyrrolyl-pyridazineamines and their use as antihypertensive agents
US4347187A (en) * 1980-10-20 1982-08-31 Syntex (U.S.A.) Inc. Process for preparing 5-aroyl 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acids and novel intermediates therein
IT1150070B (it) * 1980-12-22 1986-12-10 Lepetit Spa Procedimento per preparare derivati n-pirrolipiridazinamminici
AU8509882A (en) * 1981-06-30 1983-01-06 Merck & Co., Inc. Tricyclic derivatives of substituted pyrrole acids
EP0088128A4 (fr) * 1981-09-11 1984-04-06 Diamond Shamrock Corp 4-pyridylpyridazin(2h)-3-ones antiinflammatoires et analgesiques.
US4816454A (en) * 1984-09-21 1989-03-28 Cassella Aktiengesellschaft 4,5-dihydro-3(2H)-pyridazinones and their pharmacological use
GB8501372D0 (en) * 1985-01-18 1985-02-20 Smith Kline French Lab Chemical compounds
US5086052A (en) * 1987-07-17 1992-02-04 Abbott Laboratories Substituted 1,4,5,6-tetrahydro-2H-pyridazin-3-one and -3-thione compounds having lipoxygenase inhibitory activity
US4992441A (en) * 1987-10-14 1991-02-12 Mcneilab, Inc. 1-[[5-[[4-substituted-1-piperazinyl]methyl]-pyrrol-2-yl or furan-2-yl]methyl-2-piperidinones useful in treating schizophrenia
IE913866A1 (en) * 1990-11-28 1992-06-03 Ici Plc Aryl derivatives
DE69324820T2 (de) * 1992-09-22 2000-01-13 Univ Rochester Rochester Stabil transformierte säugertierzellen, die eine geregelte, entzündliche cyclooxygenase exprimieren
US5543297A (en) * 1992-12-22 1996-08-06 Merck Frosst Canada, Inc. Human cyclooxygenase-2 cDNA and assays for evaluating cyclooxygenase-2 activity
US5332736A (en) * 1993-11-01 1994-07-26 Ortho Pharmaceutical Corporation Anti-convulsant aroyl aminoacylpyrroles
US5622948A (en) * 1994-12-01 1997-04-22 Syntex (U.S.A.) Inc. Pyrrole pyridazine and pyridazinone anti-inflammatory agents
KR102081455B1 (ko) * 2017-06-09 2020-04-28 선상규 다중브러시를 이용한 직류발전장치

Also Published As

Publication number Publication date
PL311536A1 (en) 1996-06-10
US5622948A (en) 1997-04-22
FI955783A0 (fi) 1995-12-01
CN1132206A (zh) 1996-10-02
BR9505610A (pt) 1997-09-16
MA23735A1 (fr) 1996-07-01
HUT75117A (en) 1997-04-28
FI955783A (fi) 1996-06-02
NO954878D0 (no) 1995-11-30
CO4650183A1 (es) 1998-09-03
ZA9510027B (en) 1996-06-03
JPH08208639A (ja) 1996-08-13
AU3906295A (en) 1996-06-06
CN1066726C (zh) 2001-06-06
AR001771A1 (es) 1997-12-10
IL116139A0 (en) 1996-01-31
HU9503384D0 (en) 1996-01-29
EP0714895A1 (fr) 1996-06-05
CZ316995A3 (en) 1996-06-12
CA2163490A1 (fr) 1996-06-02
TR199501528A1 (tr) 1996-11-21
KR960022506A (ko) 1996-07-18

Similar Documents

Publication Publication Date Title
NO954878L (no) Pyrrolderivater
MY119403A (en) Novel compounds with analgesic effect.
SE9504661D0 (sv) New compounds
NO971889D0 (no) Forbindelser og sammensetninger for levering av aktive midler
HUP9901807A3 (en) Heterocycle substituted n-acyl benzenesulfonamide derivatives, process for their preparation and their use as prodrug for the preparation of pharmaceutical compositions treating inflammation or inflammation-associated disorders
AU2740797A (en) Androstene derivatives
CA2185512A1 (fr) Traitement des acouphenes a l'aide d'agents neuroprotecteurs
SE9802208D0 (sv) Novel compounds
NO983530D0 (no) Dihydrobenzofuran og relaterte forbindelser anvendelig som anti-inflammatoriske midler
NO943288L (no) Anvendelse av pentoksyfyllin ved fremstilling av farmasöytiske preparater til behandling av granulomatöse og fibroserende lungesykdommer
SE9802209D0 (sv) Novel compounds
SE9504662D0 (sv) New compounds
PT1017681E (pt) Derivados de hidrazono-benzazuleno composicoes farmaceuticas e intermediarios
FI932654A (fi) Hydroxamsyraderivat, som hindrar lipoxigenas
MY133682A (en) Substituted pyrroles
WO2000002877A3 (fr) Nouveaux composes pharmaceutiques
NO20001846L (no) Nye farmasøytisk aktive forbindelser, deres fremstilling og anvendelse som ECE-inhibitorer
IT1264428B1 (it) Composizioni farmaceutiche per il trattamento della psoriasi