NO953989L - Nye polysykliske systemer og derivater derav, som neurotransmitter-frigivelsesforsökere som er anvendbare ved behandlingav erkjennelsessykdommer - Google Patents
Nye polysykliske systemer og derivater derav, som neurotransmitter-frigivelsesforsökere som er anvendbare ved behandlingav erkjennelsessykdommerInfo
- Publication number
- NO953989L NO953989L NO953989A NO953989A NO953989L NO 953989 L NO953989 L NO 953989L NO 953989 A NO953989 A NO 953989A NO 953989 A NO953989 A NO 953989A NO 953989 L NO953989 L NO 953989L
- Authority
- NO
- Norway
- Prior art keywords
- derivatives
- treatment
- neurotransmitter release
- release assays
- assays useful
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4401293A | 1993-04-08 | 1993-04-08 | |
US08/216,881 US5594001A (en) | 1993-04-08 | 1994-03-28 | Polycyclic systems, and derivatives thereof, as neurotransmitter release enhancers useful in the treatment of cognitive disorders |
PCT/US1994/003673 WO1994024131A1 (en) | 1993-04-08 | 1994-04-04 | Novel polycyclic systems, and derivatives thereof, as neurotransmitter release enhancer useful in the treatment of cognitive disorders |
Publications (3)
Publication Number | Publication Date |
---|---|
NO953989D0 NO953989D0 (no) | 1995-10-06 |
NO953989L true NO953989L (no) | 1995-12-07 |
NO308745B1 NO308745B1 (no) | 2000-10-23 |
Family
ID=26721086
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO953989A NO308745B1 (no) | 1993-04-08 | 1995-10-06 | Nye, polycykliske forbindelser samt preparater inneholdende disse |
Country Status (21)
Country | Link |
---|---|
US (1) | US5990132A (no) |
EP (1) | EP0693069A1 (no) |
JP (1) | JPH08509713A (no) |
CN (2) | CN1058495C (no) |
AU (1) | AU690906B2 (no) |
BR (1) | BR9405954A (no) |
CA (1) | CA2160112A1 (no) |
CZ (1) | CZ251995A3 (no) |
FI (1) | FI954775A (no) |
HU (1) | HUT74104A (no) |
IL (1) | IL109237A (no) |
LV (1) | LV11179B (no) |
NO (1) | NO308745B1 (no) |
NZ (1) | NZ265183A (no) |
OA (1) | OA10235A (no) |
PL (1) | PL178570B1 (no) |
RO (1) | RO115162B1 (no) |
RU (1) | RU2152944C1 (no) |
SI (1) | SI9420022A (no) |
SK (1) | SK124695A3 (no) |
WO (1) | WO1994024131A1 (no) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5750528A (en) * | 1995-02-01 | 1998-05-12 | The Dupont Merck Pharmaceutical Company | Blockade of neuronal m-channels as a therapeutic approach to the treatment of neurological disease |
US6262081B1 (en) | 1998-07-10 | 2001-07-17 | Dupont Pharmaceuticals Company | Composition for and method of treating neurological disorders |
JP5581607B2 (ja) * | 2008-06-05 | 2014-09-03 | 住友化学株式会社 | 高分子化合物及びそれを用いた有機トランジスタ |
PT2909204T (pt) | 2012-10-12 | 2019-03-21 | Dana Farber Cancer Inst Inc | Inibidores de gsk3 e métodos de utilização dos mesmos |
KR101560061B1 (ko) * | 2012-11-30 | 2015-10-15 | 주식회사 엘지화학 | 신규한 화합물 및 이를 이용한 유기 전자 소자 |
US9593113B2 (en) | 2013-08-22 | 2017-03-14 | Bristol-Myers Squibb Company | Imide and acylurea derivatives as modulators of the glucocorticoid receptor |
WO2015027015A1 (en) | 2013-08-22 | 2015-02-26 | Bristol-Myers Squibb Company | Imidazole-derived modulators of the glucocorticoid receptor |
DK3102555T3 (da) | 2014-02-05 | 2021-08-09 | VM Oncology LLC | Sammensætninger af forbindelser og anvendelser deraf |
GB201417369D0 (en) * | 2014-10-01 | 2014-11-12 | Redx Pharma Ltd | Compounds |
MA46899A (fr) * | 2016-11-07 | 2021-04-14 | Univ Vanderbilt | Modulateurs allostériques positifs du récepteur muscarinique de l'acétylcholine m4 |
CN110958882B (zh) | 2017-04-05 | 2023-08-29 | 布罗德研究所股份有限公司 | 作为糖原合酶激酶3(gsk3)抑制剂的三环化合物及其用途 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1052346A (no) * | 1964-09-09 | |||
US4760083A (en) * | 1986-04-10 | 1988-07-26 | E. I. Dupont De Nemours & Company | 3,3-disubstituted indolines |
US5173489A (en) * | 1986-04-10 | 1992-12-22 | The Dupont Merck Pharmaceutical Co. | α,α-disubstituted aromatics and heteroaromatics as cognition enhancers |
JPH06503095A (ja) * | 1991-05-29 | 1994-04-07 | ファイザー・インコーポレーテッド | 三環式ポリヒドロキシ系のチロシンキナーゼ阻害薬 |
ES2100523T3 (es) * | 1992-01-16 | 1997-06-16 | Du Pont Merck Pharma | Nuevos liberadores de neurotransmisores utiles para la potenciacion de las facultades cognoscitivas. |
RU2051151C1 (ru) * | 1992-01-16 | 1995-12-27 | Дзе Дюпон Мерк Фармасьютикал Компани | Азотсодержащие гетероциклические производные флуорена |
US5272269A (en) * | 1992-01-16 | 1993-12-21 | The Du Pont Merck Pharmaceutical Company | Disubstituted polycyclic systems and preparative methods therefor |
US5185447A (en) * | 1992-01-29 | 1993-02-09 | Du Pont Merck Pharmaceutical Company | Polycyclic ketones and preparative methods therefor |
US5359070A (en) * | 1993-02-11 | 1994-10-25 | The Du Pont Merck Pharmaceutical Company | Unsymmetrical bis-imides as anticancer agents |
-
1994
- 1994-04-04 JP JP6523257A patent/JPH08509713A/ja active Pending
- 1994-04-04 RU RU95120594/04A patent/RU2152944C1/ru active
- 1994-04-04 NZ NZ265183A patent/NZ265183A/en unknown
- 1994-04-04 RO RO95-01753A patent/RO115162B1/ro unknown
- 1994-04-04 HU HU9502929A patent/HUT74104A/hu unknown
- 1994-04-04 SI SI9420022A patent/SI9420022A/sl unknown
- 1994-04-04 WO PCT/US1994/003673 patent/WO1994024131A1/en not_active Application Discontinuation
- 1994-04-04 CN CN94191713A patent/CN1058495C/zh not_active Expired - Fee Related
- 1994-04-04 AU AU65549/94A patent/AU690906B2/en not_active Ceased
- 1994-04-04 BR BR9405954A patent/BR9405954A/pt not_active Application Discontinuation
- 1994-04-04 PL PL94310997A patent/PL178570B1/pl unknown
- 1994-04-04 CA CA002160112A patent/CA2160112A1/en not_active Abandoned
- 1994-04-04 SK SK1246-95A patent/SK124695A3/sk unknown
- 1994-04-04 EP EP94913355A patent/EP0693069A1/en not_active Withdrawn
- 1994-04-04 CZ CZ952519A patent/CZ251995A3/cs unknown
- 1994-04-06 IL IL109237A patent/IL109237A/en not_active IP Right Cessation
-
1995
- 1995-10-06 FI FI954775A patent/FI954775A/fi unknown
- 1995-10-06 NO NO953989A patent/NO308745B1/no not_active IP Right Cessation
- 1995-10-06 OA OA60720A patent/OA10235A/en unknown
- 1995-10-09 LV LVP-95-302A patent/LV11179B/en unknown
-
1996
- 1996-06-17 US US08/664,631 patent/US5990132A/en not_active Expired - Fee Related
-
2000
- 2000-01-08 CN CN00100940A patent/CN1295072A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
CN1122135A (zh) | 1996-05-08 |
LV11179B (en) | 1997-06-20 |
FI954775A0 (fi) | 1995-10-06 |
NZ265183A (en) | 1997-11-24 |
CN1058495C (zh) | 2000-11-15 |
AU690906B2 (en) | 1998-05-07 |
JPH08509713A (ja) | 1996-10-15 |
PL310997A1 (en) | 1996-01-22 |
HUT74104A (en) | 1996-11-28 |
IL109237A0 (en) | 1994-07-31 |
NO308745B1 (no) | 2000-10-23 |
BR9405954A (pt) | 1995-12-26 |
EP0693069A1 (en) | 1996-01-24 |
WO1994024131A1 (en) | 1994-10-27 |
NO953989D0 (no) | 1995-10-06 |
LV11179A (lv) | 1996-04-20 |
CZ251995A3 (en) | 1996-01-17 |
OA10235A (en) | 1997-10-07 |
CN1295072A (zh) | 2001-05-16 |
FI954775A (fi) | 1995-10-06 |
US5990132A (en) | 1999-11-23 |
HU9502929D0 (en) | 1995-11-28 |
SK124695A3 (en) | 1996-06-05 |
RO115162B1 (ro) | 1999-11-30 |
RU2152944C1 (ru) | 2000-07-20 |
CA2160112A1 (en) | 1994-10-27 |
IL109237A (en) | 1998-02-08 |
AU6554994A (en) | 1994-11-08 |
PL178570B1 (pl) | 2000-05-31 |
SI9420022A (en) | 1996-10-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK0386997T3 (da) | Anvendelse af 4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamin-derivater i behandlingen af psykose, inflammation og som immunosuppressive midler | |
DE69433486D1 (de) | Polarisator,polarisationsplatte und verfahren zu deren herstellung | |
DK0699104T3 (da) | Fremgangsmåde til underkritisk tørring af aerogeler | |
NO985591L (no) | FremgangsmÕte ved uttak av absorberende gjenstander | |
BR9601093A (pt) | Pirido(3,2-E)pirazinoas processo para sua preparação medicamentos processo para sua preparação e utilização | |
BR9806443B1 (pt) | processo e aparelho para automaticamente compensar o volume de som. | |
NO953989L (no) | Nye polysykliske systemer og derivater derav, som neurotransmitter-frigivelsesforsökere som er anvendbare ved behandlingav erkjennelsessykdommer | |
NO903594L (no) | Fremgangsmaate for pulverisering av materialer, og anlegg til gjennomfoering av dette. | |
BR9200425A (pt) | Processo para producao de uma pelicula contraida,pelicula contraida,laminados de pelicula contraida e uso da referida pelicula | |
BR9400338A (pt) | Processo para preparação de 1,1,1,2-tetrafluoro-2-cloroetano e de pentafluoretano | |
EP0615148A3 (de) | Verfahren und Vorrichtung zur Polarisation von Licht. | |
AU5301094A (en) | Process for the recovery of valuable substances, in particular carotinoids from algae and installations suitable therefor | |
DE69021297D1 (de) | Verschlussvorrichtung, welche auch als Blendeneinrichtung nutzbar ist. | |
BR9405735A (pt) | Uso de 26,26,26,27,27,27-hexaflúor-1-alfa 25-dihidróxi colecalciferol para o tratamento de distúrbios do metabolismo do cálcio | |
ES1015823Y (es) | Soporte para cerramientos temporales de seguridad en obras y similares. | |
ES1012513Y (es) | Cejilla perfeccionada para guitarras y similares. | |
ES1024209Y (es) | Dispositivo de seguridad para exposiciones de cuadros y similares. | |
ES1026698Y (es) | Dispositivo de anclaje para focos empotrables y similares. | |
ES1028688Y (es) | Dispositivo para el cierre de joyas. | |
ITRM930432A0 (it) | Metodo per la deposizione di sistemi supramolecolari, di biomolecole ein generale, di molecole di grandi dimensioni e/o complessita' e/o labilita' senza loro frammentazione e/o perdita delle loro proprieta' strutturali e funzionali. | |
ES1024783Y (es) | Dispositivo de bloqueo para la boca de la disketera en los aparatos ordenadores. | |
ES1025016Y (es) | Dispositivo de seguridad para sujecion de colgantes en lamparas. | |
BR7301814U (pt) | Alarme multi-uso para residências, lojas e escritórios | |
ES1023768Y (es) | Dispositivo perfeccionadao para la formacion de estructuras espaciales. | |
ES1025868Y (es) | Puerta perfeccionada para grandes luces. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM1K | Lapsed by not paying the annual fees |
Free format text: LAPSED IN OCTOBER 2001 |