LV11179A - Jaunas policikliskas sistemas un to atvasinajumi ka genu-pastiprinataju atbrivosanas neiromediatori kas noderigi izzinasanas speju traucejumu arstesanai - Google Patents

Jaunas policikliskas sistemas un to atvasinajumi ka genu-pastiprinataju atbrivosanas neiromediatori kas noderigi izzinasanas speju traucejumu arstesanai

Info

Publication number
LV11179A
LV11179A LV950302A LV950302A LV11179A LV 11179 A LV11179 A LV 11179A LV 950302 A LV950302 A LV 950302A LV 950302 A LV950302 A LV 950302A LV 11179 A LV11179 A LV 11179A
Authority
LV
Latvia
Prior art keywords
neurotransmitters
disinfectant
gene
reinforced
derivatives
Prior art date
Application number
LV950302A
Other languages
English (en)
Other versions
LV11179B (en
Inventor
Christopher Allan Teleha
Wendell Wilkie Wilkerson
Richard Alan Earl
Original Assignee
Du Pont Merck Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/216,881 external-priority patent/US5594001A/en
Application filed by Du Pont Merck Pharma filed Critical Du Pont Merck Pharma
Publication of LV11179A publication Critical patent/LV11179A/lv
Publication of LV11179B publication Critical patent/LV11179B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Steroid Compounds (AREA)
LVP-95-302A 1993-04-08 1995-10-09 Novel polycyclic systems, and derivatives thereof, as neurotransmitter release enhancers useful in the treatment of cognitive disorders LV11179B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4401293A 1993-04-08 1993-04-08
US08/216,881 US5594001A (en) 1993-04-08 1994-03-28 Polycyclic systems, and derivatives thereof, as neurotransmitter release enhancers useful in the treatment of cognitive disorders
PCT/US1994/003673 WO1994024131A1 (en) 1993-04-08 1994-04-04 Novel polycyclic systems, and derivatives thereof, as neurotransmitter release enhancer useful in the treatment of cognitive disorders

Publications (2)

Publication Number Publication Date
LV11179A true LV11179A (lv) 1996-04-20
LV11179B LV11179B (en) 1997-06-20

Family

ID=26721086

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-95-302A LV11179B (en) 1993-04-08 1995-10-09 Novel polycyclic systems, and derivatives thereof, as neurotransmitter release enhancers useful in the treatment of cognitive disorders

Country Status (21)

Country Link
US (1) US5990132A (lv)
EP (1) EP0693069A1 (lv)
JP (1) JPH08509713A (lv)
CN (2) CN1058495C (lv)
AU (1) AU690906B2 (lv)
BR (1) BR9405954A (lv)
CA (1) CA2160112A1 (lv)
CZ (1) CZ251995A3 (lv)
FI (1) FI954775A0 (lv)
HU (1) HUT74104A (lv)
IL (1) IL109237A (lv)
LV (1) LV11179B (lv)
NO (1) NO308745B1 (lv)
NZ (1) NZ265183A (lv)
OA (1) OA10235A (lv)
PL (1) PL178570B1 (lv)
RO (1) RO115162B1 (lv)
RU (1) RU2152944C1 (lv)
SI (1) SI9420022A (lv)
SK (1) SK124695A3 (lv)
WO (1) WO1994024131A1 (lv)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5750528A (en) * 1995-02-01 1998-05-12 The Dupont Merck Pharmaceutical Company Blockade of neuronal m-channels as a therapeutic approach to the treatment of neurological disease
US6262081B1 (en) 1998-07-10 2001-07-17 Dupont Pharmaceuticals Company Composition for and method of treating neurological disorders
JP5581607B2 (ja) * 2008-06-05 2014-09-03 住友化学株式会社 高分子化合物及びそれを用いた有機トランジスタ
RS58700B1 (sr) 2012-10-12 2019-06-28 Broad Inst Inc Gsk3 inhibitori i postupci njihove primene
WO2014084612A1 (ko) * 2012-11-30 2014-06-05 주식회사 엘지화학 신규한 화합물 및 이를 이용한 유기 전자 소자
WO2015027021A1 (en) 2013-08-22 2015-02-26 Bristol-Myers Squibb Company Imide and acylurea derivatives as modulators of the glucocorticoid receptor
US9796720B2 (en) 2013-08-22 2017-10-24 Bristol-Myers Squibb Company Imidazole-derived modulators of the glucocorticoid receptor
ES2874533T3 (es) 2014-02-05 2021-11-05 VM Oncology LLC Composiciones de compuestos y usos de los mismos
GB201417369D0 (en) * 2014-10-01 2014-11-12 Redx Pharma Ltd Compounds
MA46899A (fr) * 2016-11-07 2021-04-14 Univ Vanderbilt Modulateurs allostériques positifs du récepteur muscarinique de l'acétylcholine m4
SG11201909115WA (en) 2017-04-05 2019-10-30 Broad Inst Inc Tricyclic compounds as glycogen synthase kinase 3 (gsk3) inhibitors and uses thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1052346A (lv) * 1964-09-09
US5173489A (en) * 1986-04-10 1992-12-22 The Dupont Merck Pharmaceutical Co. α,α-disubstituted aromatics and heteroaromatics as cognition enhancers
US4760083A (en) * 1986-04-10 1988-07-26 E. I. Dupont De Nemours & Company 3,3-disubstituted indolines
EP0586608A1 (en) * 1991-05-29 1994-03-16 Pfizer Inc. Tricyclic polyhydroxylic tyrosine kinase inhibitors
WO1993014085A1 (en) * 1992-01-16 1993-07-22 The Du Pont Merk Pharmaceutical Company Novel neurotransmitter releasers useful for cognition enhancement
RU2051151C1 (ru) * 1992-01-16 1995-12-27 Дзе Дюпон Мерк Фармасьютикал Компани Азотсодержащие гетероциклические производные флуорена
US5272269A (en) * 1992-01-16 1993-12-21 The Du Pont Merck Pharmaceutical Company Disubstituted polycyclic systems and preparative methods therefor
US5185447A (en) * 1992-01-29 1993-02-09 Du Pont Merck Pharmaceutical Company Polycyclic ketones and preparative methods therefor
US5359070A (en) * 1993-02-11 1994-10-25 The Du Pont Merck Pharmaceutical Company Unsymmetrical bis-imides as anticancer agents

Also Published As

Publication number Publication date
NZ265183A (en) 1997-11-24
RO115162B1 (ro) 1999-11-30
CZ251995A3 (en) 1996-01-17
PL178570B1 (pl) 2000-05-31
AU6554994A (en) 1994-11-08
NO953989L (no) 1995-12-07
JPH08509713A (ja) 1996-10-15
BR9405954A (pt) 1995-12-26
NO953989D0 (no) 1995-10-06
WO1994024131A1 (en) 1994-10-27
CN1122135A (zh) 1996-05-08
HUT74104A (en) 1996-11-28
PL310997A1 (en) 1996-01-22
IL109237A0 (en) 1994-07-31
CN1058495C (zh) 2000-11-15
CN1295072A (zh) 2001-05-16
CA2160112A1 (en) 1994-10-27
FI954775A (fi) 1995-10-06
HU9502929D0 (en) 1995-11-28
EP0693069A1 (en) 1996-01-24
US5990132A (en) 1999-11-23
IL109237A (en) 1998-02-08
LV11179B (en) 1997-06-20
FI954775A0 (fi) 1995-10-06
RU2152944C1 (ru) 2000-07-20
AU690906B2 (en) 1998-05-07
SK124695A3 (en) 1996-06-05
OA10235A (en) 1997-10-07
SI9420022A (en) 1996-10-31
NO308745B1 (no) 2000-10-23

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