NO953868L - Chelatorer av typen XN1S1X' for radioaktive isotoper, deres metallkomplekser og deres anvendelse i diagnostikk og terapi - Google Patents
Chelatorer av typen XN1S1X' for radioaktive isotoper, deres metallkomplekser og deres anvendelse i diagnostikk og terapiInfo
- Publication number
- NO953868L NO953868L NO953868A NO953868A NO953868L NO 953868 L NO953868 L NO 953868L NO 953868 A NO953868 A NO 953868A NO 953868 A NO953868 A NO 953868A NO 953868 L NO953868 L NO 953868L
- Authority
- NO
- Norway
- Prior art keywords
- pct
- compounds
- xn1s1x
- chelators
- diagnostics
- Prior art date
Links
- 239000002738 chelating agent Substances 0.000 title abstract 3
- 239000002184 metal Substances 0.000 title 1
- 230000002285 radioactive effect Effects 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 230000001588 bifunctional effect Effects 0.000 abstract 2
- 150000001787 chalcogens Chemical group 0.000 abstract 2
- 230000008878 coupling Effects 0.000 abstract 1
- 238000010168 coupling process Methods 0.000 abstract 1
- 238000005859 coupling reaction Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000012217 radiopharmaceutical Substances 0.000 abstract 1
- 229940121896 radiopharmaceutical Drugs 0.000 abstract 1
- 230000002799 radiopharmaceutical effect Effects 0.000 abstract 1
- 238000001959 radiotherapy Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57536—Endothelin, vasoactive intestinal contractor [VIC]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
- C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
- C07C323/59—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton with acylated amino groups bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
- C07F13/005—Compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Vascular Medicine (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4310999A DE4310999C2 (de) | 1993-03-31 | 1993-03-31 | Bifunktionelle chalkogenatom-unterbrochene Chelatbildner vom Typ XN¶1¶S¶1¶X' für radioaktive Isotope und deren Metallkomplexe, Verfahren zu ihrer Herstellung sowie diese enthaltende pharmazeutische Mittel |
| PCT/DE1994/000372 WO1994022493A1 (fr) | 1993-03-31 | 1994-03-29 | Agents chelateurs de type xn1s1x' d'isotopes radioactifs, leur complexes metalliques et leurs utilisations diagnostiques et therapeutiques |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO953868D0 NO953868D0 (no) | 1995-09-29 |
| NO953868L true NO953868L (no) | 1995-11-23 |
Family
ID=6484671
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO953868A NO953868L (no) | 1993-03-31 | 1995-09-29 | Chelatorer av typen XN1S1X' for radioaktive isotoper, deres metallkomplekser og deres anvendelse i diagnostikk og terapi |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5961954A (fr) |
| EP (1) | EP0692981B1 (fr) |
| JP (1) | JPH08511237A (fr) |
| KR (1) | KR960700762A (fr) |
| AT (1) | ATE179078T1 (fr) |
| AU (1) | AU692154B2 (fr) |
| CA (1) | CA2156619A1 (fr) |
| DE (2) | DE4310999C2 (fr) |
| HU (1) | HUT73489A (fr) |
| NO (1) | NO953868L (fr) |
| NZ (1) | NZ263795A (fr) |
| WO (1) | WO1994022493A1 (fr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4311022C2 (de) * | 1993-03-31 | 1996-07-11 | Diagnostikforschung Inst | Bifunktionelle chalkogenatom-unterbrochene Chelatbildner vom Typ S¶3¶N¶2¶ für radioaktive Isotope und deren Metallkomplexe, Verfahren zu ihrer Herstellung sowie diese enthaltende pharmazeutische Mittel |
| DE19536781A1 (de) * | 1995-09-21 | 1997-03-27 | Diagnostikforschung Inst | Bifunktionelle sulfidhaltige Sulfonamid-Chelatbildner vom Typ XSNS für radioaktive Isotope |
| DE19536785A1 (de) * | 1995-09-21 | 1997-03-27 | Diagnostikforschung Inst | Bifunktionelle sulfidhaltige Sulfonamid-Chelatbildner vom Typ S¶2¶NY für radioaktive Isotope |
| DE19652374A1 (de) * | 1996-12-04 | 1998-06-10 | Schering Ag | Verwendung von Endothelin-Konjugaten in der Therapie, neue Endothelin-Konjugate, diese enthaltende Mittel, sowie Verfahren zu deren Herstellung |
| PT2260875E (pt) * | 2002-05-06 | 2014-06-25 | Endocyte Inc | Agentes de imagiologia direcionados para recetor de folato |
| US20080058674A1 (en) * | 2006-08-29 | 2008-03-06 | Lex Jansen | Tissue extraction device and method of using the same |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57188527A (en) * | 1981-04-21 | 1982-11-19 | Amersham Int Plc | Diagnosis of kidney function |
| EP0089143A1 (fr) * | 1982-03-16 | 1983-09-21 | AMERSHAM INTERNATIONAL plc | Diagnostic pour le fonctionnement des reins |
| US4980147A (en) * | 1984-06-25 | 1990-12-25 | University Of Utah Research Foundation | Radiolabeled technetium chelates for use in renal function determinations |
| DE3680924D1 (de) * | 1985-01-14 | 1991-09-26 | Neorx Corp | Metall-radionuklid markiertes protein fuer diagnose und therapie. |
| DE3762624D1 (de) * | 1986-05-28 | 1990-06-13 | Mallinckrodt Inc | Technetiumchelate fuer die bestimmung der nierenfunktion. |
| US4861869A (en) * | 1986-05-29 | 1989-08-29 | Mallinckrodt, Inc. | Coupling agents for joining radionuclide metal ions with biologically useful proteins |
| US5198208A (en) * | 1987-07-16 | 1993-03-30 | Nycomed Imaging As | Aminopolycarboxylic acids and derivatives thereof |
| AU1995392A (en) * | 1991-05-08 | 1992-12-21 | Mallinckrodt Medical, Inc. | Technetium chelates to be used for determining the renal function |
| JPH0570484A (ja) * | 1991-09-12 | 1993-03-23 | Hitachi Chem Co Ltd | ペプチドおよびその塩 |
| AU3610593A (en) * | 1992-02-06 | 1993-09-03 | Mallinckrodt Medical, Inc. | Ligands for improving metal chelate formation kinetics |
| DE4311023C2 (de) * | 1993-03-31 | 1996-05-02 | Diagnostikforschung Inst | Bifunktionelle chalkogenatom-unterbrochene Chelatbildner von Typ XN¶1¶S¶1¶O¶1¶ für radioaktive Isotope, deren Metallkomplexe, Verfahren zu ihrer Herstellung sowie diese enthaltende pharmazeutische Mittel |
| DE4311021A1 (de) * | 1993-03-31 | 1994-10-27 | Diagnostikforschung Inst | Bifunktionelle Chelatbildner, deren Technetium- und Rhenium-Komplexe, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende radiopharmazeutische Mittel |
| DE4311022C2 (de) * | 1993-03-31 | 1996-07-11 | Diagnostikforschung Inst | Bifunktionelle chalkogenatom-unterbrochene Chelatbildner vom Typ S¶3¶N¶2¶ für radioaktive Isotope und deren Metallkomplexe, Verfahren zu ihrer Herstellung sowie diese enthaltende pharmazeutische Mittel |
-
1993
- 1993-03-31 DE DE4310999A patent/DE4310999C2/de not_active Expired - Lifetime
-
1994
- 1994-03-29 AT AT94912442T patent/ATE179078T1/de not_active IP Right Cessation
- 1994-03-29 NZ NZ263795A patent/NZ263795A/en unknown
- 1994-03-29 US US08/530,326 patent/US5961954A/en not_active Expired - Fee Related
- 1994-03-29 JP JP6521543A patent/JPH08511237A/ja active Pending
- 1994-03-29 WO PCT/DE1994/000372 patent/WO1994022493A1/fr active IP Right Grant
- 1994-03-29 AU AU65018/94A patent/AU692154B2/en not_active Ceased
- 1994-03-29 EP EP94912442A patent/EP0692981B1/fr not_active Expired - Lifetime
- 1994-03-29 HU HU9502869A patent/HUT73489A/hu unknown
- 1994-03-29 DE DE59408144T patent/DE59408144D1/de not_active Expired - Lifetime
- 1994-03-29 KR KR1019950703670A patent/KR960700762A/ko not_active Application Discontinuation
- 1994-03-29 CA CA002156619A patent/CA2156619A1/fr not_active Abandoned
-
1995
- 1995-09-29 NO NO953868A patent/NO953868L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR960700762A (ko) | 1996-02-24 |
| JPH08511237A (ja) | 1996-11-26 |
| DE4310999A1 (de) | 1994-10-06 |
| US5961954A (en) | 1999-10-05 |
| WO1994022493A1 (fr) | 1994-10-13 |
| ATE179078T1 (de) | 1999-05-15 |
| EP0692981B1 (fr) | 1999-04-21 |
| HU9502869D0 (en) | 1995-11-28 |
| DE4310999C2 (de) | 1996-07-18 |
| AU692154B2 (en) | 1998-06-04 |
| NO953868D0 (no) | 1995-09-29 |
| AU6501894A (en) | 1994-10-24 |
| EP0692981A1 (fr) | 1996-01-24 |
| DE59408144D1 (de) | 1999-05-27 |
| NZ263795A (en) | 1997-01-29 |
| HUT73489A (en) | 1996-08-28 |
| CA2156619A1 (fr) | 1994-10-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO303732B1 (no) | Porfyrinkompleksforbindelser, farmasoytisk middel inneholdende minst ett av disse og anvendelse av minst ett av disse for fremstilling av midler for NMR- eller radiodiagnostikk, samt for radioterapi | |
| FI102892B1 (fi) | Kelaatinmuodostaja radioaktiivisten isotooppien kompleksointiin, sen metallikompleksit ja näiden käyttö diagnostiikassa | |
| DE3477884D1 (en) | Bisamide bisthiol compounds useful for making technetium radiodiagnostic renal agents | |
| ATE76401T1 (de) | Durch estergruppen substituierte diamindithiole und davon abgeleitete radioaktiv markierte komplexe. | |
| NO953867L (no) | Chelatorer av typen XN1S1O1 for radioaktive isotoper, deres metallkomplekser og deres anvendelse i diagnostikk og terapi | |
| EP0692978A4 (fr) | Formulations radiopharmaceutiques ayant des agents reducteurs non stanneux | |
| NO953868L (no) | Chelatorer av typen XN1S1X' for radioaktive isotoper, deres metallkomplekser og deres anvendelse i diagnostikk og terapi | |
| WO1997010852A3 (fr) | Agents de chelation amidosulfoniques sulfures bifonctionnels du type xsns pour isotopes radioactifs | |
| WO1997010853A3 (fr) | Agents de formation de chelates de nicotinamide bifonctionnels du type n2s2 pour isotopes radioactifs | |
| HU9502867D0 (en) | Type s3n2 chelators for radioactive isotopes, their metal complexes and their diagnostic and therapeutical use | |
| WO1997012636A3 (fr) | Agents de chelation amidosulfoniques sulfures bifonctionnels du type s2ny pour isotopes radioactifs | |
| HU9501878D0 (en) | Derivated dtpa complexes, pharmaceuticals containing these compounds, their use as nmr-and radiographic contrasting agents and process for producing the same | |
| PL312794A1 (en) | Tris(isonitril)copper sulphates(i) for production of complexes of radioactive nuclides | |
| CA2064063A1 (fr) | Preparation d'agents therapeutiques a base de phosphonate de rhenium | |
| NZ213567A (en) | Radioactive aminocarboxylic acid complexes for treatment of calcified tumours | |
| JPH05502219A (ja) | 安定な治療用放射性核種およびそれを調製する方法 | |
| NO961743L (no) | N-alkyl-peptid-chelatdannere, deres metallkomplekser med radionuklider, fremgangsmåte ved deres fremstilling og radiofarmasöytiske sammensetninger inneholdende disse forbindelser | |
| JPH03148289A (ja) | テクネチウム―９９ｍジオキシム―イミン錯体のボロン酸付加体 | |
| ES8705389A1 (es) | Un procedimiento para preparar una sal de quelato con heterociclo nitrogenado | |
| WO1997012850A3 (fr) | Agents chelateurs bifonctionnels au sulfonamide de type xsny contenant des sulfures pour isotopes radioactifs |