NO953560D0 - Genetiske suppressorelementer assosiert med sensitivitet overfor kjemoterapeutiske medikamenter - Google Patents

Genetiske suppressorelementer assosiert med sensitivitet overfor kjemoterapeutiske medikamenter

Info

Publication number
NO953560D0
NO953560D0 NO953560A NO953560A NO953560D0 NO 953560 D0 NO953560 D0 NO 953560D0 NO 953560 A NO953560 A NO 953560A NO 953560 A NO953560 A NO 953560A NO 953560 D0 NO953560 D0 NO 953560D0
Authority
NO
Norway
Prior art keywords
sensitivity
chemotherapeutic drugs
elements associated
genetic suppressor
suppressor elements
Prior art date
Application number
NO953560A
Other languages
English (en)
Other versions
NO953560L (no
Inventor
Igor B Roninson
Andrei Gudkov
Original Assignee
Univ Illinois
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Illinois filed Critical Univ Illinois
Publication of NO953560D0 publication Critical patent/NO953560D0/no
Publication of NO953560L publication Critical patent/NO953560L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1072Differential gene expression library synthesis, e.g. subtracted libraries, differential screening
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1079Screening libraries by altering the phenotype or phenotypic trait of the host
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1082Preparation or screening gene libraries by chromosomal integration of polynucleotide sequences, HR-, site-specific-recombination, transposons, viral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67General methods for enhancing the expression
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90Isomerases (5.)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/44Multiple drug resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
NO953560A 1993-03-09 1995-09-08 Genetiske suppressorelementer assosiert med sensitivitet overfor kjemoterapeutiske medikamenter NO953560L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3308693A 1993-03-09 1993-03-09
PCT/US1994/002519 WO1994020618A1 (en) 1993-03-09 1994-03-08 Genetic suppressor elements associated with sensitivity to chemotherapeutic drugs

Publications (2)

Publication Number Publication Date
NO953560D0 true NO953560D0 (no) 1995-09-08
NO953560L NO953560L (no) 1995-11-02

Family

ID=21868485

Family Applications (1)

Application Number Title Priority Date Filing Date
NO953560A NO953560L (no) 1993-03-09 1995-09-08 Genetiske suppressorelementer assosiert med sensitivitet overfor kjemoterapeutiske medikamenter

Country Status (9)

Country Link
EP (1) EP0694068B1 (no)
JP (1) JPH08507919A (no)
KR (1) KR100267837B1 (no)
AT (1) ATE232557T1 (no)
CA (1) CA2157770A1 (no)
DE (1) DE69432120T2 (no)
NO (1) NO953560L (no)
WO (1) WO1994020618A1 (no)
ZA (1) ZA941637B (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5753432A (en) * 1990-10-19 1998-05-19 Board Of Trustees Of The University Of Illinois Genes and genetic elements associated with control of neoplastic transformation in mammalian cells
JPH09508006A (ja) * 1994-01-05 1997-08-19 ボード・オブ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・イリノイ キネシンと化学療法薬に対する感受性との関連
US6001632A (en) * 1996-05-15 1999-12-14 Incyte Pharmaceuticals, Inc. Human protein disulfide isomerase
US5798249A (en) * 1996-05-15 1998-08-25 Incyte Pharmaceuticals, Inc. Human protein disulfide isomerase
ATE304591T1 (de) * 1997-12-19 2005-09-15 Hk Pharmaceuticals Inc Nicht-bakterielles klonierungssystem zur verabreichung und expression von nukleinsäuren
DE69933856D1 (de) 1998-02-13 2006-12-14 Koester Hubert Verwendung von ribozymen zur bestimmung der funktion von genen
WO1999053098A1 (en) * 1998-04-09 1999-10-21 Iconix Pharmaceuticals Inc. Methods for identifying genetic determinants associated with modulation of test compound activity
WO2000053743A1 (en) * 1999-03-12 2000-09-14 Gpc Biotech, Inc. Methods and reagents for identifying synthetic genetic elements
WO2001040458A2 (en) * 1999-12-02 2001-06-07 Signalgene Inc. Preparation of sequence libraries from non-denatured rna and kits therefor
EP1276861A2 (en) * 2000-03-24 2003-01-22 Maxygen, Inc. Methods for modulating cellular and organismal phenotypes

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5217889A (en) * 1990-10-19 1993-06-08 Roninson Igor B Methods and applications for efficient genetic suppressor elements

Also Published As

Publication number Publication date
WO1994020618A1 (en) 1994-09-15
JPH08507919A (ja) 1996-08-27
EP0694068B1 (en) 2003-02-12
EP0694068A1 (en) 1996-01-31
NO953560L (no) 1995-11-02
DE69432120T2 (de) 2003-12-11
KR960701202A (ko) 1996-02-24
KR100267837B1 (ko) 2001-03-02
DE69432120D1 (de) 2003-03-20
ZA941637B (en) 1995-02-22
CA2157770A1 (en) 1994-09-15
ATE232557T1 (de) 2003-02-15

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