NO953437D0 - Inhibitorer for Herpes virus ribonukleotid-reduktase - Google Patents

Inhibitorer for Herpes virus ribonukleotid-reduktase

Info

Publication number
NO953437D0
NO953437D0 NO953437A NO953437A NO953437D0 NO 953437 D0 NO953437 D0 NO 953437D0 NO 953437 A NO953437 A NO 953437A NO 953437 A NO953437 A NO 953437A NO 953437 D0 NO953437 D0 NO 953437D0
Authority
NO
Norway
Prior art keywords
alkyl
nhch
amino acid
inhibitors
herpes virus
Prior art date
Application number
NO953437A
Other languages
English (en)
Norwegian (no)
Other versions
NO953437L (no
Inventor
Robert Deziel
Neil Moss
Original Assignee
Bio Mega Boehringer Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Mega Boehringer Ingelheim filed Critical Bio Mega Boehringer Ingelheim
Publication of NO953437L publication Critical patent/NO953437L/no
Publication of NO953437D0 publication Critical patent/NO953437D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
NO953437A 1993-03-03 1995-09-01 Inhibitorer for Herpes virus ribonukleotid-reduktase NO953437D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2554093A 1993-03-03 1993-03-03
PCT/CA1994/000106 WO1994020528A1 (en) 1993-03-03 1994-02-28 Inhibitors of herpes viral ribonucleotide reductase

Publications (2)

Publication Number Publication Date
NO953437L NO953437L (no) 1995-09-01
NO953437D0 true NO953437D0 (no) 1995-09-01

Family

ID=21826675

Family Applications (1)

Application Number Title Priority Date Filing Date
NO953437A NO953437D0 (no) 1993-03-03 1995-09-01 Inhibitorer for Herpes virus ribonukleotid-reduktase

Country Status (27)

Country Link
US (1) US5476841A (de)
EP (1) EP0618226B1 (de)
JP (1) JPH08507760A (de)
KR (1) KR960701090A (de)
CN (1) CN1118601A (de)
AT (1) ATE197802T1 (de)
AU (1) AU683450B2 (de)
BG (1) BG99889A (de)
BR (1) BR9406346A (de)
CA (1) CA2157196C (de)
CZ (1) CZ224295A3 (de)
DE (1) DE69426337T2 (de)
DK (1) DK0618226T3 (de)
ES (1) ES2152269T3 (de)
FI (1) FI954048A0 (de)
GR (1) GR3035295T3 (de)
HU (1) HUT72894A (de)
IL (1) IL108818A0 (de)
LV (1) LV11037B (de)
NO (1) NO953437D0 (de)
NZ (1) NZ262073A (de)
PL (1) PL310447A1 (de)
PT (1) PT618226E (de)
SG (1) SG65553A1 (de)
SK (1) SK106095A3 (de)
WO (1) WO1994020528A1 (de)
ZA (1) ZA941449B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5846941A (en) * 1992-03-12 1998-12-08 Boehringer Ingelheim (Canada) Ltd. Isosteric antiherpes peptide derivatives II
US5830864A (en) * 1992-03-12 1998-11-03 Boehringer Ingelheim (Canada), Ltd. Antiherpes peptide derivatives having a ureido n-terminus
CA2152541C (en) * 1995-06-23 1998-12-15 Boehringer Ingelheim (Canada) Ltd./ Boehringer Ingelheim (Canada) Ltee Herpes ribonucleotide reductase inhibitors
US5948935A (en) * 1997-01-23 1999-09-07 Boehringer Ingelheim (Canada) Ltd. Process and intermediates for (s)-α-amino-1-carboxycyclopentaneacetic acid
US8029815B2 (en) * 2004-04-28 2011-10-04 Elford Howard L Methods for treating or preventing restenosis and other vascular proliferative disorders
EP2030615A3 (de) * 2007-08-13 2009-12-02 ELFORD, Howard L. Ribonukleotidreduktase-Inhibitoren zur Verwendung für die Behandlung oder Vorbeugung von Nervenentzündung- oder Autoimmunerkrankungen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE118785T1 (de) * 1989-07-07 1995-03-15 Bio Mega Boehringer Ingelheim Pentapeptidderivate, wirksam gegen herpes, die eine ersetzte asparaginsäureseitenkette enthalten.
JPH03181498A (ja) * 1989-12-07 1991-08-07 Merck & Co Inc ペプチド抗ウイルス剤
CA2033448C (en) * 1990-12-31 1996-11-26 Boehringer Ingelheim (Canada) Ltd./ Boehringer Ingelheim (Canada) Ltee Antiherpes compositions and method of use

Also Published As

Publication number Publication date
NO953437L (no) 1995-09-01
AU683450B2 (en) 1997-11-13
BR9406346A (pt) 1996-02-21
ES2152269T3 (es) 2001-02-01
FI954048A (fi) 1995-08-29
ATE197802T1 (de) 2000-12-15
JPH08507760A (ja) 1996-08-20
IL108818A0 (en) 1994-06-24
ZA941449B (en) 1994-10-14
SK106095A3 (en) 1996-02-07
PL310447A1 (en) 1995-12-11
CA2157196C (en) 2000-06-13
HU9502570D0 (en) 1995-11-28
AU6151694A (en) 1994-09-26
EP0618226A1 (de) 1994-10-05
CN1118601A (zh) 1996-03-13
DK0618226T3 (da) 2000-12-27
NZ262073A (en) 1997-07-27
FI954048A0 (fi) 1995-08-29
PT618226E (pt) 2001-03-30
GR3035295T3 (en) 2001-04-30
CZ224295A3 (en) 1996-02-14
DE69426337T2 (de) 2001-05-31
LV11037A (lv) 1996-02-20
DE69426337D1 (de) 2001-01-04
CA2157196A1 (en) 1994-09-15
HUT72894A (en) 1996-06-28
US5476841A (en) 1995-12-19
SG65553A1 (en) 1999-06-22
EP0618226B1 (de) 2000-11-29
WO1994020528A1 (en) 1994-09-15
BG99889A (en) 1996-02-28
KR960701090A (ko) 1996-02-24
LV11037B (en) 1996-06-20

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NO953437L (no) Inhibitorer for Herpes virus ribonukleotid-reduktase
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