NO951891D0 - Perfluoralkylsubstituerte benzoylguanidiner, fremgangsmåte for fremstilling derav, deres anvendelse som medikament eller diagnostikum samt medikament inneholdende forbindelsen - Google Patents

Perfluoralkylsubstituerte benzoylguanidiner, fremgangsmåte for fremstilling derav, deres anvendelse som medikament eller diagnostikum samt medikament inneholdende forbindelsen

Info

Publication number
NO951891D0
NO951891D0 NO951891A NO951891A NO951891D0 NO 951891 D0 NO951891 D0 NO 951891D0 NO 951891 A NO951891 A NO 951891A NO 951891 A NO951891 A NO 951891A NO 951891 D0 NO951891 D0 NO 951891D0
Authority
NO
Norway
Prior art keywords
perfluoroalkyl
diagnostic
drug
processes
compound
Prior art date
Application number
NO951891A
Other languages
English (en)
Other versions
NO951891L (no
NO304307B1 (no
Inventor
Hans-Werner Kleemann
Hans-Jochen Lang
Jan-Robert Schwark
Andreas Weichert
Wolfgang Scholz
Udo Albus
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO951891D0 publication Critical patent/NO951891D0/no
Publication of NO951891L publication Critical patent/NO951891L/no
Publication of NO304307B1 publication Critical patent/NO304307B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C07C317/46—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Pathology (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Vascular Medicine (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pyrrole Compounds (AREA)
NO951891A 1994-05-13 1995-05-12 Perfluoralkylsubstituerte benzoylguanidiner, deres anvendelse for fremstilling av medikamenter eller diagnostika, samt medikament inneholdende forbindelsen NO304307B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4417004A DE4417004A1 (de) 1994-05-13 1994-05-13 Perfluoralkyl-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Publications (3)

Publication Number Publication Date
NO951891D0 true NO951891D0 (no) 1995-05-12
NO951891L NO951891L (no) 1995-11-14
NO304307B1 NO304307B1 (no) 1998-11-30

Family

ID=6518126

Family Applications (1)

Application Number Title Priority Date Filing Date
NO951891A NO304307B1 (no) 1994-05-13 1995-05-12 Perfluoralkylsubstituerte benzoylguanidiner, deres anvendelse for fremstilling av medikamenter eller diagnostika, samt medikament inneholdende forbindelsen

Country Status (17)

Country Link
US (1) US5571842A (no)
EP (1) EP0686627B1 (no)
JP (1) JP3802582B2 (no)
KR (1) KR100376194B1 (no)
CN (1) CN1054373C (no)
AT (1) ATE169903T1 (no)
AU (1) AU687521B2 (no)
CA (1) CA2149285C (no)
DE (2) DE4417004A1 (no)
DK (1) DK0686627T3 (no)
ES (1) ES2121256T3 (no)
FI (1) FI952290A (no)
HU (1) HU223537B1 (no)
IL (1) IL113688A (no)
NO (1) NO304307B1 (no)
NZ (1) NZ272103A (no)
TW (1) TW418185B (no)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4412334A1 (de) * 1994-04-11 1995-10-19 Hoechst Ag Substituierte N-Heteroaroylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4430916A1 (de) * 1994-08-31 1996-03-07 Merck Patent Gmbh Alkyl-benzoylguanidin-Derivate
DE19517848A1 (de) * 1995-05-16 1996-11-21 Merck Patent Gmbh Fluorhaltige Benzoylguanidine
US5847172A (en) * 1995-06-07 1998-12-08 Magainin Pharmaceuticals Inc. Certain aminosterol compounds and pharmaceutical compositions including these compounds
US5994336A (en) * 1995-06-07 1999-11-30 Magainin Pharmaceuticals Inc. Method of inhibiting proliferation of cells by administering an aminosterol compound
DE19531138A1 (de) * 1995-08-24 1997-02-27 Merck Patent Gmbh Alkenyl-benzoylguanidin-Derivate
EP0765867A1 (de) * 1995-09-27 1997-04-02 Hoechst Aktiengesellschaft Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Antiarrhytmika oder Diagnostikum sowie sie enthaltendes Medikament
DE19540995A1 (de) * 1995-11-03 1997-05-07 Hoechst Ag Substituierte Sulfonimidamide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19542306A1 (de) * 1995-11-14 1997-05-15 Hoechst Ag Sulfonylamino-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
PL316439A1 (en) * 1995-11-20 1997-05-26 Hoechst Ag Novel substituted derivatives of benzoyloguanidine, method of obtaining them, their application in production of pharmaceutic and diagnostic agents and pharmaceutic agent as such
DE19546736A1 (de) * 1995-12-14 1997-06-19 Hoechst Ag Substituierte Chromanylsulfonyl(thio)harnstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung pharmazeutischer Präparate
DE19608161A1 (de) 1996-03-04 1997-09-11 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19621319A1 (de) * 1996-05-28 1997-12-04 Hoechst Ag Bis-ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
US7214711B2 (en) * 1998-12-23 2007-05-08 Neurotherapeutics Pharma Llc Method of treating migraine headache without aura
US6495601B1 (en) 1998-12-23 2002-12-17 Cytoscan Sciences Llc Methods and compositions for treating conditions of the central and peripheral nervous systems using non-synaptic mechanisms
US8722668B2 (en) * 1998-12-23 2014-05-13 Daryl W. Hochman Methods and compositions for the treatment of neuropathic pain and neuropsychiatric disorders
US20060025387A1 (en) * 1998-12-23 2006-02-02 Cytoscan Sciences Llc Compositions and methods for the treatment of disorders of the central and peripheral nervous systems
AU2384500A (en) * 1998-12-23 2000-07-12 Cytoscan Sciences L.L.C. Compounds, methods of screening and methods of treatment for central and peripheral nervous system disorders
US8008283B2 (en) * 1998-12-23 2011-08-30 Neurotherapeutics Pharma, Inc. Methods and compositions for the treatment of neuropsychiatric disorders
US7375138B2 (en) * 2002-05-18 2008-05-20 Sanofi-Aventis Deutschland Gmbh Pentafluorosulfanylbenzoylguanidines, processes for their preparation, their use as medicaments or diagnostic aids, and medicaments comprising them
DE10222192A1 (de) * 2002-05-18 2003-11-27 Aventis Pharma Gmbh Pentafluorsulfuranyl-benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE10226462A1 (de) * 2002-06-13 2003-12-24 Aventis Pharma Gmbh Fluorierte Cycloalkyl-derivatisierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, sowie sie enthaltendes Medikament
US6878748B2 (en) * 2002-06-13 2005-04-12 Aventis Pharma Deutschland Gmbh Fluorinated cycloalkyl-derivatized benzoylguanidines, process for their preparation, their uses as medicament, and medicament containing them
DE10338554A1 (de) * 2003-08-22 2005-03-31 Aventis Pharma Deutschland Gmbh Pentafluorosulfanylphenyl-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
US7381841B2 (en) * 2003-08-22 2008-06-03 Sanofi-Aventis Deutschland Gmbh Pentafluorosulfanylphenyl-substituted benzoylguanidines, processes for their preparation, their use as medicament or diagnostic aid, and medicament comprising them
DE10353204A1 (de) * 2003-11-13 2005-06-16 Aventis Pharma Deutschland Gmbh Verfahren zur Herstellung von 4-Pentafluorsulfanyl-benzoylguanidinen
OA13285A (en) * 2003-11-13 2007-01-31 Sanofi Aventis Deutschland Pentafluorosulfanyl benzoylguanidines, method for their production, their use as medicaments or diagnostic agents and medicament containing the same.
US20050124666A1 (en) * 2003-11-13 2005-06-09 Aventis Pharma Deutschland Gmbh Pentafluorosulfanylbenzoylguanidines, process for their preparation, use as a medicament or diagnostic aid, and medicament comprising same
JP2009511629A (ja) * 2005-10-17 2009-03-19 ニューロセラピューティクス ファーマ， インコーポレイテッド 中枢神経系疾患の調節に有用な利尿薬様化合物類似体
KR200484534Y1 (ko) 2017-07-18 2017-09-20 김경학 조립식 베개

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3780027A (en) * 1970-04-29 1973-12-18 Merck & Co Inc Anthranilic acid derivatives
DE3929582A1 (de) * 1989-09-06 1991-03-07 Hoechst Ag Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament
EP0556673B1 (de) * 1992-02-15 1997-09-17 Hoechst Aktiengesellschaft Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
ATE139526T1 (de) * 1992-02-15 1996-07-15 Hoechst Ag 3,5-substituierte benzoylguanidine, mit antiarrythmischer wirkung und inhibierender wirkung auf die proliferationen von zellen
DE59304166D1 (de) * 1992-07-01 1996-11-21 Hoechst Ag 3,4,5-Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
TW250477B (no) * 1992-12-15 1995-07-01 Hoechst Ag
DE4318658A1 (de) * 1993-06-04 1994-12-08 Hoechst Ag Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Also Published As

Publication number Publication date
HU223537B1 (hu) 2004-08-30
KR950032098A (ko) 1995-12-20
HUT71800A (en) 1996-02-28
ATE169903T1 (de) 1998-09-15
CN1054373C (zh) 2000-07-12
AU1799995A (en) 1995-11-23
EP0686627B1 (de) 1998-08-19
IL113688A (en) 1999-06-20
TW418185B (en) 2001-01-11
FI952290A0 (fi) 1995-05-11
AU687521B2 (en) 1998-02-26
KR100376194B1 (ko) 2003-05-17
EP0686627A3 (de) 1996-01-31
ES2121256T3 (es) 1998-11-16
HU9501407D0 (en) 1995-06-28
CA2149285C (en) 2007-09-18
DE59503234D1 (de) 1998-09-24
JPH07304729A (ja) 1995-11-21
CA2149285A1 (en) 1995-11-14
NZ272103A (en) 1996-10-28
EP0686627A2 (de) 1995-12-13
DE4417004A1 (de) 1995-11-16
NO951891L (no) 1995-11-14
CN1126201A (zh) 1996-07-10
JP3802582B2 (ja) 2006-07-26
IL113688A0 (en) 1995-08-31
FI952290A (fi) 1995-11-14
US5571842A (en) 1996-11-05
DK0686627T3 (da) 1999-05-25
NO304307B1 (no) 1998-11-30

Similar Documents

Publication Publication Date Title
NO951891L (no) Perfluoralkylsubstituerte benzoylguanidiner, fremgangsmåte for fremstilling derav, deres anvendelse som medikament eller diagnostikum samt medikament inneholdende forbindelsen
BR9407832A (pt) Fenilsulfoniluréias processo para sua preparação e seu uso como herbicida e reguladores de crescimento de plantas
NO952450D0 (no) Fenylsubstituerte alkenylkarboksylsyreguanidider som bærer perfluoralkylgrupper, fremgangsmåte for fremstilling derav, deres anvendelse som medikament eller diagnostikum samt mediakament inneholdende forbindelsen
SE7514518L (sv) Azolyl-(1)-metaner och salter derav till anvendning som lekemedel och sett for deras framstellning
NO945015D0 (no) Substituerte 1-oxo-1,2-dihydro-isochinolinoyl- og 1,1-dioxo-2H-1,2-benzotiazinoylguanidiner, fremgangsmåte for fremstilling og anvendelse som medikament eller diagnostikum
ES2184770T3 (es) Guanididas de acido alquil-carboxilico sustituidas con fenilo y portadoras de grupos pperfluoralquilo, procedimiento para su preparacion, su uso como medicamento o agente de diagnostico asi como medicamentos que las contienen.
NO872409D0 (no) Substituerte 4-benzylpiperazinyl-forbindelser.
NO305751B1 (no) Substituerte benzensulfonylurinstoffer og -tiourinstoffer, deres anvendelse for fremstilling av medikament eller diagnostikum, sÕvel som legemidler inneholdende forbindelsene
FI954190A (fi) Heterosykli-N-oksidisubstituoituja bentsoyyliguanidiinejä, menetelmä niiden valmistamiseksi, niiden käyttö lääkeaineena tai diagnostisena aineena sekä välituotteita niiden valmistamiseksi
NO305242B1 (no) Arylbenzoylguanidiner, farmas°ytiske preparater som inneholder minst Ún slik forbindelse, samt anvendelse av forbindelsene til fremstilling av legemidler
ATE108775T1 (de) N-phenyl-piperidyl-4-amine und diese enthaltende arzneimittel.
SE7708900L (sv) Herbicida foreningar och medel samt framstellning derav
NO305243B1 (no) Benzoylguanidinderivater, farmas°ytiske preparater som inneholder minst Ún slik forbindelse, samt anvendelse av forbindelsene til fremstilling av et legemiddel
FI954257A0 (fi) Bisyklisen oksatsolin ja tiatsolin substituoituja eettereitä
PT89147A (pt) Processo para a preparacao de novas feniletanolaminas e de composicoes farmaceuticas e de estimulantes de potencia ou de nutrientes para animais que as contem
NL7304808A (en) Bis-imidazolium cpds - for use as bactericides

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees