NO950221L - Nye asyliske amidingruppeinneholdende difosfonsyrederivater, fremgangsmåte for fremstilling derav samt legemidler inneholdende slike - Google Patents

Nye asyliske amidingruppeinneholdende difosfonsyrederivater, fremgangsmåte for fremstilling derav samt legemidler inneholdende slike

Info

Publication number
NO950221L
NO950221L NO950221A NO950221A NO950221L NO 950221 L NO950221 L NO 950221L NO 950221 A NO950221 A NO 950221A NO 950221 A NO950221 A NO 950221A NO 950221 L NO950221 L NO 950221L
Authority
NO
Norway
Prior art keywords
pct
carbon atoms
possibly
preparation
alkyl
Prior art date
Application number
NO950221A
Other languages
English (en)
Other versions
NO304792B1 (no
NO950221D0 (no
Inventor
Harald Zilch
Frieder Bauss
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of NO950221L publication Critical patent/NO950221L/no
Publication of NO950221D0 publication Critical patent/NO950221D0/no
Publication of NO304792B1 publication Critical patent/NO304792B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/3804Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se) not used, see subgroups
    • C07F9/3839Polyphosphonic acids
    • C07F9/3873Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
NO945015A 1992-07-21 1995-01-20 Nye asykliske amidingruppeinneholdende difosfonsyrederivater, anvendelse derav for fremstilling av le gemidler samt legemidler inneholdende slike NO304792B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4223940A DE4223940A1 (de) 1992-07-21 1992-07-21 Neue acyclische Amidingruppen-haltige Diphosphonsäurederivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
PCT/EP1993/001833 WO1994002492A1 (de) 1992-07-21 1993-07-13 Neue acyclische amidingruppen-haltige diphosphonsäurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel

Publications (3)

Publication Number Publication Date
NO950221L true NO950221L (no) 1995-01-20
NO950221D0 NO950221D0 (no) 1995-01-20
NO304792B1 NO304792B1 (no) 1999-02-15

Family

ID=6463698

Family Applications (1)

Application Number Title Priority Date Filing Date
NO945015A NO304792B1 (no) 1992-07-21 1995-01-20 Nye asykliske amidingruppeinneholdende difosfonsyrederivater, anvendelse derav for fremstilling av le gemidler samt legemidler inneholdende slike

Country Status (20)

Country Link
US (1) US5543561A (no)
EP (1) EP0651757B1 (no)
JP (1) JP3489830B2 (no)
KR (1) KR100246809B1 (no)
CN (1) CN1040110C (no)
AT (1) ATE148467T1 (no)
AU (1) AU670307B2 (no)
CA (1) CA2138127C (no)
DE (2) DE4223940A1 (no)
DK (1) DK0651757T3 (no)
ES (1) ES2099960T3 (no)
FI (1) FI109698B (no)
GR (1) GR3023109T3 (no)
HU (1) HU221496B (no)
IL (1) IL106393A (no)
MX (1) MX9304313A (no)
NO (1) NO304792B1 (no)
NZ (1) NZ254130A (no)
WO (1) WO1994002492A1 (no)
ZA (1) ZA935224B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW258729B (no) * 1992-06-22 1995-10-01 Ciba Geigy
US6298081B1 (en) 1996-05-31 2001-10-02 Telefonaktiebolaget Lm Ericsson (Publ) Channel hopping in a radio communications system
KR100327786B1 (ko) * 1999-03-25 2002-03-14 유승필 4-아미노-1-하이드록시부틸리덴-1,1-비스포스폰산 또는 이의 염의 제조방법
MXPA02010740A (es) * 2000-05-05 2003-03-10 Hoffmann La Roche Composicion farmaceutica similar al gel para la administracion subcutanea que comprende acidos bisfosfonicos o sus sales.
KR100327787B1 (ko) * 2001-02-27 2002-03-15 유승필 4-아미노-1-하이드록시부틸리덴-1,1-비스포스폰산 일나트륨 삼수화물의 제조방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1196315B (it) * 1984-10-29 1988-11-16 Gentili Ist Spa Procedimento per la preparazione di acidi difosfonici
DE3930130A1 (de) * 1989-09-09 1991-03-21 Boehringer Mannheim Gmbh Neue amidingruppen-haltige diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
EP0531253B1 (en) * 1991-08-27 1997-01-08 Ciba-Geigy Ag N-substituted aminomethanediphosphonic acids
TW222637B (no) * 1991-12-12 1994-04-21 Hoechst Ag
TW258729B (no) * 1992-06-22 1995-10-01 Ciba Geigy
EP0600371B1 (de) * 1992-12-02 1999-02-03 Hoechst Aktiengesellschaft Guanidinalkyl-1, 1-bisphosphonsäurederivate, Verfahren zu ihrer Herstellung und ihre Verwendung
US5366965A (en) * 1993-01-29 1994-11-22 Boehringer Mannheim Gmbh Regimen for treatment or prophylaxis of osteoporosis

Also Published As

Publication number Publication date
CA2138127A1 (en) 1994-02-03
HU221496B (en) 2002-10-28
EP0651757A1 (de) 1995-05-10
KR100246809B1 (ko) 2000-04-01
NO304792B1 (no) 1999-02-15
FI950259A0 (fi) 1995-01-20
JP3489830B2 (ja) 2004-01-26
IL106393A0 (en) 1993-11-15
WO1994002492A1 (de) 1994-02-03
EP0651757B1 (de) 1997-01-29
JPH09502158A (ja) 1997-03-04
GR3023109T3 (en) 1997-07-30
ES2099960T3 (es) 1997-06-01
CN1084852A (zh) 1994-04-06
MX9304313A (es) 1994-02-28
DK0651757T3 (da) 1997-07-28
DE59305351D1 (de) 1997-03-13
HU9500180D0 (en) 1995-03-28
CN1040110C (zh) 1998-10-07
ATE148467T1 (de) 1997-02-15
NZ254130A (en) 1996-11-26
DE4223940A1 (de) 1994-01-27
NO950221D0 (no) 1995-01-20
AU4568093A (en) 1994-02-14
CA2138127C (en) 2006-01-24
IL106393A (en) 1999-05-09
FI950259A (fi) 1995-01-20
US5543561A (en) 1996-08-06
HUT72603A (en) 1996-05-28
KR950702566A (ko) 1995-07-29
AU670307B2 (en) 1996-07-11
ZA935224B (en) 1995-01-20
FI109698B (fi) 2002-09-30

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Legal Events

Date Code Title Description
MK1K Patent expired