NO943847D0 - Process for preparing macrocyclic chelating agents and forming chelates and conjugates thereof - Google Patents

Process for preparing macrocyclic chelating agents and forming chelates and conjugates thereof

Info

Publication number
NO943847D0
NO943847D0 NO943847A NO943847A NO943847D0 NO 943847 D0 NO943847 D0 NO 943847D0 NO 943847 A NO943847 A NO 943847A NO 943847 A NO943847 A NO 943847A NO 943847 D0 NO943847 D0 NO 943847D0
Authority
NO
Norway
Prior art keywords
conjugates
chelating agents
macrocyclic chelating
forming chelates
preparing macrocyclic
Prior art date
Application number
NO943847A
Other languages
Norwegian (no)
Other versions
NO943847L (en
Inventor
Roberta C Cheng
William A Fordyce
Jr William J Kruper
George R Litwinski
Original Assignee
Dow Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Chemical Co filed Critical Dow Chemical Co
Publication of NO943847D0 publication Critical patent/NO943847D0/en
Publication of NO943847L publication Critical patent/NO943847L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6524—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1093—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having three nitrogen atoms as the only ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
NO943847A 1992-04-13 1994-10-12 Process for preparing macrocyclic chelating agents and forming chelates and conjugates thereof NO943847L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86807892A 1992-04-13 1992-04-13
PCT/US1993/003483 WO1993020852A2 (en) 1992-04-13 1993-04-13 Macrocyclic chelating agents, chelates and conjugates thereof

Publications (2)

Publication Number Publication Date
NO943847D0 true NO943847D0 (en) 1994-10-12
NO943847L NO943847L (en) 1994-10-12

Family

ID=25351031

Family Applications (1)

Application Number Title Priority Date Filing Date
NO943847A NO943847L (en) 1992-04-13 1994-10-12 Process for preparing macrocyclic chelating agents and forming chelates and conjugates thereof

Country Status (7)

Country Link
EP (1) EP0662842A1 (en)
JP (1) JPH07505886A (en)
AU (1) AU694074B2 (en)
CA (1) CA2117775A1 (en)
NO (1) NO943847L (en)
SG (1) SG52470A1 (en)
WO (1) WO1993020852A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE258806T1 (en) * 1994-09-07 2004-02-15 Dow Chemical Co METHOD FOR PRODUCING MACROCYCLIC AGENTS AND THEIR CHELATES AND CONJUGATES
JP5006032B2 (en) * 2003-04-15 2012-08-22 アルゲッタ エイエス Use of thorium-227 in radiotherapy of soft tissue diseases
US20090208421A1 (en) 2008-02-19 2009-08-20 Dominique Meyer Process for preparing a pharmaceutical formulation of contrast agents
JP5376130B2 (en) * 2009-03-24 2013-12-25 独立行政法人日本原子力研究開発機構 Separation and purification of carrier-free 177Lu capable of antibody labeling
GB201002508D0 (en) 2010-02-12 2010-03-31 Algeta As Product

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4885363A (en) * 1987-04-24 1989-12-05 E. R. Squibb & Sons, Inc. 1-substituted-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs
US4994560A (en) * 1987-06-24 1991-02-19 The Dow Chemical Company Functionalized polyamine chelants and radioactive rhodium complexes thereof for conjugation to antibodies
IL90730A0 (en) * 1988-06-24 1990-01-18 Dow Chemical Co Macrocyclic bifunctional chelants,complexes thereof and their antibody conjugates
JP2930708B2 (en) * 1988-12-23 1999-08-03 ザ ダウ ケミカル カンパニー Method for producing isothiocyanato-functionalized metal complex

Also Published As

Publication number Publication date
JPH07505886A (en) 1995-06-29
WO1993020852A3 (en) 1993-11-25
NO943847L (en) 1994-10-12
SG52470A1 (en) 1998-09-28
WO1993020852A2 (en) 1993-10-28
AU694074B2 (en) 1998-07-09
CA2117775A1 (en) 1993-10-28
AU677006B2 (en) 1997-04-10
AU4285093A (en) 1993-11-18
EP0662842A1 (en) 1995-07-19
AU2856397A (en) 1997-10-30

Similar Documents

Publication Publication Date Title
HU912755D0 (en) Water-soluble taxole derivatives and process for producing said compounds
NO970444L (en) Process for the preparation of metals and other elements
HU9202347D0 (en) Chelate producing agents
NO176438C (en) Tris-maleimido compounds and trivalent coupling agent
SK60895A3 (en) Taxane derivatives and process for their preparation
EP0475731A3 (en) Development process
DK0635004T3 (en) 4-Diphenylmethylpiperidine derivatives and process for their preparation
EP0446034A3 (en) Development apparatus
GB2240104B (en) New arylvinylamide derivatives and process for their preparation
ZA915595B (en) Carbostyril derivatives
DE69114260T2 (en) Pipe connection and process therefor.
NO964551D0 (en) Imidazole derivatives and process for their preparation
NO943847D0 (en) Process for preparing macrocyclic chelating agents and forming chelates and conjugates thereof
EP0459465A3 (en) Hiv-protease inhibitors and process for their preparation
EP0485749A3 (en) Chemical modification of antibodies for creating of immunoconjugates
ZA911927B (en) Labdanes and process for their preparation
CS199791A3 (en) Aminodiole derivatives and process for preparing thereof
EP0443796A3 (en) Development process
EP0554358A4 (en) Chelating agents
AU3216289A (en) Paramagnetic compounds comprising chelating moiety, linker group macro molecule and paramagnetic metal
DE69101944D1 (en) Gas dispenser and method.
EP0482867A3 (en) Development apparatus
EP0460465A3 (en) Process for the preparation of styrene derivatives having a double bond in an ethylene-extended chain and ethylene-extended styrene derivatives
DE440606T1 (en) Macrocyclic chelating agents and chelates made therefrom.
HUT64426A (en) Cash gate for toys