SG52470A1 - Process for preparing macrocyclic chelating agents and formation of chelates and conjugates thereof - Google Patents
Process for preparing macrocyclic chelating agents and formation of chelates and conjugates thereofInfo
- Publication number
- SG52470A1 SG52470A1 SG1996004996A SG1996004996A SG52470A1 SG 52470 A1 SG52470 A1 SG 52470A1 SG 1996004996 A SG1996004996 A SG 1996004996A SG 1996004996 A SG1996004996 A SG 1996004996A SG 52470 A1 SG52470 A1 SG 52470A1
- Authority
- SG
- Singapore
- Prior art keywords
- chelates
- conjugates
- formation
- chelating agents
- macrocyclic chelating
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title 1
- 239000002738 chelating agent Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6524—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1093—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having three nitrogen atoms as the only ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86807892A | 1992-04-13 | 1992-04-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG52470A1 true SG52470A1 (en) | 1998-09-28 |
Family
ID=25351031
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG1996004996A SG52470A1 (en) | 1992-04-13 | 1993-04-13 | Process for preparing macrocyclic chelating agents and formation of chelates and conjugates thereof |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0662842A1 (en) |
| JP (1) | JPH07505886A (en) |
| AU (1) | AU694074B2 (en) |
| CA (1) | CA2117775A1 (en) |
| NO (1) | NO943847D0 (en) |
| SG (1) | SG52470A1 (en) |
| WO (1) | WO1993020852A2 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0783326B1 (en) * | 1994-09-07 | 2004-02-04 | The Dow Chemical Company | Process for preparing macrocyclic chelating agents and formation of chelates and conjugates thereof |
| EP1617876B1 (en) * | 2003-04-15 | 2014-05-14 | Algeta AS | Thorium-227 for use in radiotherapy of soft tissue disease |
| US20090208421A1 (en) | 2008-02-19 | 2009-08-20 | Dominique Meyer | Process for preparing a pharmaceutical formulation of contrast agents |
| JP5376130B2 (en) * | 2009-03-24 | 2013-12-25 | 独立行政法人日本原子力研究開発機構 | Separation and purification of carrier-free 177Lu capable of antibody labeling |
| GB201002508D0 (en) | 2010-02-12 | 2010-03-31 | Algeta As | Product |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4885363A (en) * | 1987-04-24 | 1989-12-05 | E. R. Squibb & Sons, Inc. | 1-substituted-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs |
| US4994560A (en) * | 1987-06-24 | 1991-02-19 | The Dow Chemical Company | Functionalized polyamine chelants and radioactive rhodium complexes thereof for conjugation to antibodies |
| DE353450T1 (en) * | 1988-06-24 | 1990-09-06 | The Dow Chemical Co., Midland, Mich. | MACROCYCLIC BIFUNCTIONAL CHELATORS, COMPLEXES OF THEM AND THEIR CONJUGATED ANTIBODIES. |
| BR8907282A (en) * | 1988-12-23 | 1991-03-12 | Dow Chemical Co | PROCESS TO PREPARE METAL COMPLEXES OPERATED WITH ISOTIOCIANATE |
-
1993
- 1993-04-13 SG SG1996004996A patent/SG52470A1/en unknown
- 1993-04-13 JP JP5518572A patent/JPH07505886A/en active Pending
- 1993-04-13 CA CA 2117775 patent/CA2117775A1/en not_active Abandoned
- 1993-04-13 WO PCT/US1993/003483 patent/WO1993020852A2/en not_active Application Discontinuation
- 1993-04-13 EP EP93912231A patent/EP0662842A1/en not_active Ceased
-
1994
- 1994-10-12 NO NO943847A patent/NO943847D0/en unknown
-
1997
- 1997-07-09 AU AU28563/97A patent/AU694074B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| NO943847L (en) | 1994-10-12 |
| AU694074B2 (en) | 1998-07-09 |
| AU2856397A (en) | 1997-10-30 |
| AU4285093A (en) | 1993-11-18 |
| JPH07505886A (en) | 1995-06-29 |
| NO943847D0 (en) | 1994-10-12 |
| WO1993020852A3 (en) | 1993-11-25 |
| EP0662842A1 (en) | 1995-07-19 |
| AU677006B2 (en) | 1997-04-10 |
| CA2117775A1 (en) | 1993-10-28 |
| WO1993020852A2 (en) | 1993-10-28 |
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