NO941781L - Ikke-radioaktiv immunanalyse - Google Patents
Ikke-radioaktiv immunanalyseInfo
- Publication number
- NO941781L NO941781L NO941781A NO941781A NO941781L NO 941781 L NO941781 L NO 941781L NO 941781 A NO941781 A NO 941781A NO 941781 A NO941781 A NO 941781A NO 941781 L NO941781 L NO 941781L
- Authority
- NO
- Norway
- Prior art keywords
- assay
- peptide
- modified
- modified product
- enzyme
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/80—Fluorescent dyes, e.g. rhodamine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/103332—Bilirubin or uric acid standard or control
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/104165—Lipid, cholesterol, or triglyceride standard or control
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/104998—Glucose, ketone, nitrate standard or control
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/105831—Protein or peptide standard or control [e.g., hemoglobin, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/106664—Blood serum or blood plasma standard or control
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Analysebestemmelse og rensing av proteiner, og spesielt en ikke-radio-aktiv analysebestemmelse og rensing av proteinkinaser, fosfataser og prote-aser, ved inkubasjon av enzymet med et modifisert substratpeptid for å danne et modifisert produktpeptid under be-tingelser hvor enzymet er aktivt. Det modifiserte produktpeptid og det modifiserte substratpeptid atskilles der-etter, og det modifiserte produktpeptid måles. Analysesett og biologiske reagenser for utførelse av analyse-bestemmelsene er også beskrevet.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US79192891A | 1991-11-12 | 1991-11-12 | |
PCT/US1992/009595 WO1993010461A1 (en) | 1991-11-12 | 1992-11-12 | Non-radioactive enzyme assay |
Publications (2)
Publication Number | Publication Date |
---|---|
NO941781D0 NO941781D0 (no) | 1994-05-11 |
NO941781L true NO941781L (no) | 1994-06-29 |
Family
ID=25155249
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO941781A NO941781L (no) | 1991-11-12 | 1994-05-11 | Ikke-radioaktiv immunanalyse |
Country Status (7)
Country | Link |
---|---|
US (1) | US5580747A (no) |
EP (1) | EP0646242A4 (no) |
JP (1) | JPH07501444A (no) |
AU (1) | AU3129493A (no) |
CA (1) | CA2121842A1 (no) |
NO (1) | NO941781L (no) |
WO (1) | WO1993010461A1 (no) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5527688A (en) * | 1994-04-08 | 1996-06-18 | Pierce Chemical Company | Rapid assays for protein kinase activity |
US5698411A (en) * | 1995-05-18 | 1997-12-16 | Coulter Corporation | Method for determining activity of enzymes in metabolically active whole cells |
US5733719A (en) * | 1995-05-18 | 1998-03-31 | Coulter Corporation | Method of making an assay compound |
WO1996036729A1 (en) * | 1995-05-18 | 1996-11-21 | Coulter International Corp. | An assay reagent and a method of making and using the assay reagent |
US5776720A (en) * | 1995-05-18 | 1998-07-07 | Coulter Corporation | Assay reagent |
US5871946A (en) * | 1995-05-18 | 1999-02-16 | Coulter Corporation | Method for determining activity of enzymes in metabolically active whole cells |
US5747276A (en) * | 1995-09-15 | 1998-05-05 | The Scripps Research Institute | Screening methods for the identification of novel antibiotics |
US20030036106A1 (en) * | 1996-10-28 | 2003-02-20 | Burke Thomas J. | Kinase and phosphatase activity measurement using fluorescence polarization |
EP0938586A4 (en) * | 1996-10-28 | 2002-01-30 | Panvera Corp | MEASURING KINASE ACTIVITY BY MEANS OF FLUORESCENT POLARISATION |
AU6770398A (en) * | 1997-03-28 | 1998-10-22 | Mycotox, Inc. | Histidine kinase assay |
US6342611B1 (en) | 1997-10-10 | 2002-01-29 | Cytovia, Inc. | Fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for capsases and other enzymes and the use thereof |
US6974676B1 (en) * | 1998-01-12 | 2005-12-13 | Roar Holding, Llc | Assay methods for transfer proteins that normalize for acceptor concentration |
JP3091176B2 (ja) * | 1998-02-18 | 2000-09-25 | 株式会社ヘレナ研究所 | 分離分析検査データ処理装置 |
US5869275A (en) * | 1998-07-20 | 1999-02-09 | Huang; Eric Z. | Affinity ultrafiltration assay for transferase activity |
WO2000004914A1 (en) | 1998-07-21 | 2000-02-03 | Cytovia, Inc. | Novel fluorescence dyes and their applications for whole cell fluorescence screening assays for caspases, peptidases, proteases and other enzymes and the use thereof |
US6410255B1 (en) * | 1999-05-05 | 2002-06-25 | Aurora Biosciences Corporation | Optical probes and assays |
US6562571B1 (en) * | 1999-05-25 | 2003-05-13 | University Of Rochester | Human heme-regulated initiation factor 2-α kinase |
US6280965B1 (en) | 1999-05-26 | 2001-08-28 | Nova Southeastern University | Simple non-radioactive assay for estimating protein kinase C and protein phosphatase-1 |
AU2001265231B2 (en) * | 2000-05-31 | 2006-07-06 | Promega Corporation | Assay for kinases and phosphatases |
AU2001278135A1 (en) | 2000-08-03 | 2002-02-18 | Cytovia, Inc. | Method of identifying immunosuppressive agents |
EP1199370B1 (en) * | 2000-10-18 | 2004-04-21 | Evotec OAI AG | Process for detecting dephosphorylation of phosphorylated threonine or serine by phosphatase activity |
US6942778B1 (en) * | 2000-11-28 | 2005-09-13 | Nanogen, Inc. | Microstructure apparatus and method for separating differently charged molecules using an applied electric field |
WO2002043828A2 (en) * | 2000-11-28 | 2002-06-06 | Nanogen, Inc. | Microtiter plate format device and methods for separating differently charged molecules using an electric field |
US20020123068A1 (en) * | 2001-01-31 | 2002-09-05 | Dwyer Brian P. | Water-soluble, fluorescent, & electrophoretically mobile peptidic substrates for enzymatic reactions and methods for their use in high-throughput screening assays |
US7291698B2 (en) | 2001-09-04 | 2007-11-06 | Stephen Eliot Zweig | Synthetic substrate for high specificity enzymatic assays |
AU2002339973B2 (en) * | 2001-09-24 | 2007-10-18 | Applied Genetics Incorporated Dermatics | Stabilization of T4 endonuclease V |
GB0126976D0 (en) * | 2001-11-09 | 2002-01-02 | Microsens Biophage Ltd | Multiple virus reaction assay |
US6942987B2 (en) * | 2002-05-15 | 2005-09-13 | Pharmacopeia Drug Discovery, Inc. | Methods for measuring kinase activity |
US7195884B2 (en) * | 2002-07-19 | 2007-03-27 | Promega Corp. | Methods and kits for transferases |
US7619059B2 (en) | 2003-07-29 | 2009-11-17 | Life Technologies Corporation | Bimolecular optical probes |
CA2445420A1 (en) | 2003-07-29 | 2005-01-29 | Invitrogen Corporation | Kinase and phosphatase assays |
US7727752B2 (en) | 2003-07-29 | 2010-06-01 | Life Technologies Corporation | Kinase and phosphatase assays |
US20070231838A1 (en) * | 2006-04-03 | 2007-10-04 | Garton Andrew J | Method for the assay of rock kinase activity in cells |
WO2009100447A2 (en) | 2008-02-08 | 2009-08-13 | The Regents Of The University Of California | Detection of degradative enzymes and biomolecules in bodily fluids |
DE102010019245A1 (de) * | 2010-05-03 | 2012-01-19 | Basf Coatings Gmbh | Verfahren zur autophoretischen Beschichtung, Beschichtungsmittel und Mehrschichtlackierung |
WO2012145399A2 (en) * | 2011-04-20 | 2012-10-26 | Traxxsson, Llc | Methods of diagnosing cancer in a patient |
US9187567B2 (en) | 2011-05-18 | 2015-11-17 | Parkinson's Institute | Assay to determine LRRK2 activity in parkinson's disease |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4016258A (en) * | 1975-08-05 | 1977-04-05 | Said Sami I | Vasoactive intestinal peptide from fowl |
US4681842A (en) * | 1983-01-12 | 1987-07-21 | Boehringer Mannheim Gmbh | Process and reagent for the differentiated determination of isoenzymes of alkaline phosphatase |
US4687732A (en) * | 1983-06-10 | 1987-08-18 | Yale University | Visualization polymers and their application to diagnostic medicine |
DE3485587D1 (de) * | 1983-08-16 | 1992-04-23 | Univ Georgia Res Found | Herstellung von aminocyclopropancarbonsaeuren und von peptiden. |
US4748111A (en) * | 1984-03-12 | 1988-05-31 | Molecular Diagnostics, Inc. | Nucleic acid-protein conjugate used in immunoassay |
EP0155854B1 (en) * | 1984-03-22 | 1990-09-26 | Bresatec Limited | Non-radioactive biological probes |
US4912033A (en) * | 1985-11-14 | 1990-03-27 | Washington University | Creatine kinase MB determination method |
US4803157A (en) * | 1986-01-31 | 1989-02-07 | Eastman Kodak Company | Hydrolyzable fluorescent substrates for phosphatases and analytical use thereof |
ATE79635T1 (de) * | 1986-04-01 | 1992-09-15 | Wako Pure Chem Ind Ltd | Peptid-derivate und methode zur messung der wirksamkeit von physiologisch aktiven verbindungen, die dieselben als substraten benuetzen. |
JPH0821004B2 (ja) * | 1987-08-31 | 1996-03-04 | 富士通株式会社 | データ処理装置のデータ保護方式 |
JP2866872B2 (ja) * | 1989-03-14 | 1999-03-08 | 工業技術院長 | 血圧降下剤 |
US5242801A (en) * | 1990-08-06 | 1993-09-07 | University Of Iowa Research Foundation | Diagnosing malignant hyperthermia susceptibility by detection of abnormal proteolytic enzyme digestion fragments of the ryanodine receptor |
-
1992
- 1992-11-12 EP EP92925108A patent/EP0646242A4/en not_active Withdrawn
- 1992-11-12 WO PCT/US1992/009595 patent/WO1993010461A1/en not_active Application Discontinuation
- 1992-11-12 JP JP5509337A patent/JPH07501444A/ja active Pending
- 1992-11-12 AU AU31294/93A patent/AU3129493A/en not_active Abandoned
- 1992-11-12 CA CA002121842A patent/CA2121842A1/en not_active Abandoned
-
1994
- 1994-01-21 US US08/185,448 patent/US5580747A/en not_active Expired - Fee Related
- 1994-05-11 NO NO941781A patent/NO941781L/no unknown
Also Published As
Publication number | Publication date |
---|---|
CA2121842A1 (en) | 1993-05-27 |
EP0646242A1 (en) | 1995-04-05 |
WO1993010461A1 (en) | 1993-05-27 |
US5580747A (en) | 1996-12-03 |
AU3129493A (en) | 1993-06-15 |
EP0646242A4 (en) | 1997-12-03 |
NO941781D0 (no) | 1994-05-11 |
JPH07501444A (ja) | 1995-02-16 |
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