NO940853L - Acyloksyheksansyrederivater - Google Patents

Acyloksyheksansyrederivater

Info

Publication number
NO940853L
NO940853L NO940853A NO940853A NO940853L NO 940853 L NO940853 L NO 940853L NO 940853 A NO940853 A NO 940853A NO 940853 A NO940853 A NO 940853A NO 940853 L NO940853 L NO 940853L
Authority
NO
Norway
Prior art keywords
substituted
compounds
formula
carbon atoms
unsubstituted
Prior art date
Application number
NO940853A
Other languages
English (en)
Other versions
NO940853D0 (no
Inventor
Guido Bold
Marc Lang
Alexander Fassler
Hans-Georg Capraro
Shripad Bhagwat
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO940853D0 publication Critical patent/NO940853D0/no
Publication of NO940853L publication Critical patent/NO940853L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06052—Val-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Det blir beskrevet forbindelser med formel (!') V ^ H (I1) hvor T står for et acylradlkal med formel (Z), RZ 0-C (Z) hvor RZ står for Ikke-substltuert eller substituert hydrokarbyl hvor minst et av karbonatomene er erstattet med et heteroatcm med den forutsetning at et heteroaton Ikke er bundet direkte på karbonylet, på hvilken resten Rz er bundet, alkyl med 2 eller nere karbonatomer, lavalkenyl, lavalklnyl, aryl eller ikke-substltuert eller substituert amlno, og hvor restene RI( B1§ R2, RS, Aj, A2 og NR4R5 har betydningen son nevnt l beskrivelsen, og forløpere av disse. Forbindelsene er farmasøytisk vlrksonae blant annet for behandling av AIDS.
NO940853A 1993-03-11 1994-03-10 Acyloksyheksansyrederivater NO940853L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH77293 1993-03-11

Publications (2)

Publication Number Publication Date
NO940853D0 NO940853D0 (no) 1994-03-10
NO940853L true NO940853L (no) 1994-09-12

Family

ID=4194824

Family Applications (1)

Application Number Title Priority Date Filing Date
NO940853A NO940853L (no) 1993-03-11 1994-03-10 Acyloksyheksansyrederivater

Country Status (15)

Country Link
EP (1) EP0618222A3 (no)
JP (1) JPH07316191A (no)
KR (1) KR940021577A (no)
CN (1) CN1112125A (no)
AU (1) AU678202B2 (no)
CA (1) CA2118661A1 (no)
CZ (1) CZ54194A3 (no)
FI (1) FI941064A (no)
HU (1) HUT67089A (no)
IL (1) IL108920A0 (no)
MA (1) MA23133A1 (no)
MX (1) MXPA94001822A (no)
NO (1) NO940853L (no)
NZ (1) NZ260056A (no)
ZA (1) ZA941668B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT708085E (pt) * 1994-10-19 2002-11-29 Novartis Ag Eteres antivirais de isosteros de substrato de aspartato protease
US6037157A (en) 1995-06-29 2000-03-14 Abbott Laboratories Method for improving pharmacokinetics
KR100440643B1 (ko) * 1999-01-28 2004-07-21 쥬가이 세이야쿠 가부시키가이샤 치환 페네틸아민 유도체
WO2002042259A2 (en) * 2000-11-27 2002-05-30 University Of Maryland, Baltimore Methods of synthesizing and using derivatives of [2-(2-aminoethoxy)ethoxy] acetic acid
US7479538B2 (en) 2004-11-12 2009-01-20 The Zhabilov Trust Irreversibly-inactivated pepsinogen fragment and pharmaceutical compositions comprising the same for detecting, preventing, and treating HIV
US8067531B2 (en) 2004-11-12 2011-11-29 The Zhabilov Trust Inactivated pepsin fragments for modulating immune system activity against human malignant tumor cells
US8309072B2 (en) 2004-11-12 2012-11-13 The Zhabilov Trust Irreversibly-inactivated pepsinogen fragments for modulating immune function

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0532466A3 (en) * 1991-09-12 1993-06-16 Ciba-Geigy Ag Derivatives of 5-amino-4-hydroxy-hexanoic acid and their therapeutical use

Also Published As

Publication number Publication date
MXPA94001822A (es) 2004-09-09
CZ54194A3 (en) 1994-10-19
CA2118661A1 (en) 1994-09-12
EP0618222A3 (en) 1997-01-02
AU5758894A (en) 1994-09-15
FI941064A (fi) 1994-09-12
HU9400720D0 (en) 1994-06-28
ZA941668B (en) 1994-09-13
NZ260056A (en) 1995-12-21
MA23133A1 (fr) 1994-10-01
AU678202B2 (en) 1997-05-22
IL108920A0 (en) 1994-06-24
KR940021577A (ko) 1994-10-19
FI941064A0 (fi) 1994-03-07
CN1112125A (zh) 1995-11-22
JPH07316191A (ja) 1995-12-05
HUT67089A (en) 1995-01-30
EP0618222A2 (de) 1994-10-05
NO940853D0 (no) 1994-03-10

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