NO940853L - Acyloksyheksansyrederivater - Google Patents
AcyloksyheksansyrederivaterInfo
- Publication number
- NO940853L NO940853L NO940853A NO940853A NO940853L NO 940853 L NO940853 L NO 940853L NO 940853 A NO940853 A NO 940853A NO 940853 A NO940853 A NO 940853A NO 940853 L NO940853 L NO 940853L
- Authority
- NO
- Norway
- Prior art keywords
- substituted
- compounds
- formula
- carbon atoms
- unsubstituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
- C07K5/06052—Val-amino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Crystallography & Structural Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
Det blir beskrevet forbindelser med formel (!') V ^ H (I1) hvor T står for et acylradlkal med formel (Z), RZ 0-C (Z) hvor RZ står for Ikke-substltuert eller substituert hydrokarbyl hvor minst et av karbonatomene er erstattet med et heteroatcm med den forutsetning at et heteroaton Ikke er bundet direkte på karbonylet, på hvilken resten Rz er bundet, alkyl med 2 eller nere karbonatomer, lavalkenyl, lavalklnyl, aryl eller ikke-substltuert eller substituert amlno, og hvor restene RI( B1§ R2, RS, Aj, A2 og NR4R5 har betydningen son nevnt l beskrivelsen, og forløpere av disse. Forbindelsene er farmasøytisk vlrksonae blant annet for behandling av AIDS.Compounds of formula (I) V 1 H (I1) wherein T stands for an acyl radical of formula (Z), R 2 O-C (Z) wherein R 2 represents Unsubstituted or substituted hydrocarbyl wherein at least one of the carbon atoms is disclosed is substituted with a heteroate with the proviso that a heteroatone is not bonded directly to the carbonyl to which the residue R 2 is attached, alkyl of 2 or lower carbon atoms, lavalkenyl, lower alkyl, aryl or unsubstituted or substituted amino, and wherein the residues R 1 ( B1§ R2, RS, Aj, A2 and NR4R5 have the meaning as mentioned in the description, and precursors thereof, the compounds being pharmaceutical sites for the treatment of AIDS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH77293 | 1993-03-11 |
Publications (2)
Publication Number | Publication Date |
---|---|
NO940853D0 NO940853D0 (en) | 1994-03-10 |
NO940853L true NO940853L (en) | 1994-09-12 |
Family
ID=4194824
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO940853A NO940853L (en) | 1993-03-11 | 1994-03-10 | Acyloksyheksansyrederivater |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0618222A3 (en) |
JP (1) | JPH07316191A (en) |
KR (1) | KR940021577A (en) |
CN (1) | CN1112125A (en) |
AU (1) | AU678202B2 (en) |
CA (1) | CA2118661A1 (en) |
CZ (1) | CZ54194A3 (en) |
FI (1) | FI941064A (en) |
HU (1) | HUT67089A (en) |
IL (1) | IL108920A0 (en) |
MA (1) | MA23133A1 (en) |
MX (1) | MXPA94001822A (en) |
NO (1) | NO940853L (en) |
NZ (1) | NZ260056A (en) |
ZA (1) | ZA941668B (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT708085E (en) * | 1994-10-19 | 2002-11-29 | Novartis Ag | PROTEASE ASPARTATE SUBSTRATE ISOSTERATE ETERIS ANTERIORS |
US6037157A (en) | 1995-06-29 | 2000-03-14 | Abbott Laboratories | Method for improving pharmacokinetics |
EP1149843A4 (en) * | 1999-01-28 | 2012-06-06 | Chugai Pharmaceutical Co Ltd | Substituted phenethylamine derivatives |
AU2002237684A1 (en) | 2000-11-27 | 2002-06-03 | University Of Maryland, Baltimore | Methods of synthesizing and using derivatives of (2-(2-aminoethoxy)ethoxy) acetic acid |
US7479538B2 (en) | 2004-11-12 | 2009-01-20 | The Zhabilov Trust | Irreversibly-inactivated pepsinogen fragment and pharmaceutical compositions comprising the same for detecting, preventing, and treating HIV |
US8067531B2 (en) | 2004-11-12 | 2011-11-29 | The Zhabilov Trust | Inactivated pepsin fragments for modulating immune system activity against human malignant tumor cells |
US8309072B2 (en) | 2004-11-12 | 2012-11-13 | The Zhabilov Trust | Irreversibly-inactivated pepsinogen fragments for modulating immune function |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0532466A3 (en) * | 1991-09-12 | 1993-06-16 | Ciba-Geigy Ag | Derivatives of 5-amino-4-hydroxy-hexanoic acid and their therapeutical use |
-
1994
- 1994-03-02 EP EP94810133A patent/EP0618222A3/en not_active Withdrawn
- 1994-03-04 AU AU57588/94A patent/AU678202B2/en not_active Ceased
- 1994-03-07 FI FI941064A patent/FI941064A/en not_active Application Discontinuation
- 1994-03-09 CA CA002118661A patent/CA2118661A1/en not_active Abandoned
- 1994-03-09 NZ NZ260056A patent/NZ260056A/en unknown
- 1994-03-09 CZ CZ94541A patent/CZ54194A3/en unknown
- 1994-03-10 ZA ZA941668A patent/ZA941668B/en unknown
- 1994-03-10 HU HU9400720A patent/HUT67089A/en unknown
- 1994-03-10 NO NO940853A patent/NO940853L/en unknown
- 1994-03-10 IL IL10892094A patent/IL108920A0/en unknown
- 1994-03-10 CN CN94104099A patent/CN1112125A/en active Pending
- 1994-03-10 MA MA23440A patent/MA23133A1/en unknown
- 1994-03-10 KR KR1019940004652A patent/KR940021577A/en not_active Application Discontinuation
- 1994-03-11 MX MXPA94001822A patent/MXPA94001822A/en unknown
- 1994-03-11 JP JP6067908A patent/JPH07316191A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0618222A2 (en) | 1994-10-05 |
ZA941668B (en) | 1994-09-13 |
CA2118661A1 (en) | 1994-09-12 |
NO940853D0 (en) | 1994-03-10 |
CZ54194A3 (en) | 1994-10-19 |
AU5758894A (en) | 1994-09-15 |
JPH07316191A (en) | 1995-12-05 |
FI941064A0 (en) | 1994-03-07 |
EP0618222A3 (en) | 1997-01-02 |
MXPA94001822A (en) | 2004-09-09 |
IL108920A0 (en) | 1994-06-24 |
NZ260056A (en) | 1995-12-21 |
AU678202B2 (en) | 1997-05-22 |
MA23133A1 (en) | 1994-10-01 |
KR940021577A (en) | 1994-10-19 |
CN1112125A (en) | 1995-11-22 |
FI941064A (en) | 1994-09-12 |
HU9400720D0 (en) | 1994-06-28 |
HUT67089A (en) | 1995-01-30 |
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