NO940028L - - Google Patents

Info

Publication number
NO940028L
NO940028L NO940028A NO940028A NO940028L NO 940028 L NO940028 L NO 940028L NO 940028 A NO940028 A NO 940028A NO 940028 A NO940028 A NO 940028A NO 940028 L NO940028 L NO 940028L
Authority
NO
Norway
Prior art keywords
alkyl
formula
group
hydrogen
phenyl
Prior art date
Application number
NO940028A
Other languages
English (en)
Norwegian (no)
Other versions
NO940028D0 (no
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO940028D0 publication Critical patent/NO940028D0/no
Publication of NO940028L publication Critical patent/NO940028L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22Bridged ring systems
    • C07D221/28Morphinans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO940028A 1993-01-06 1994-01-04 O-aryletere av morfinaner NO940028D0 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US113593A 1993-01-06 1993-01-06

Publications (2)

Publication Number Publication Date
NO940028D0 NO940028D0 (no) 1994-01-04
NO940028L true NO940028L (OSRAM) 1994-07-07

Family

ID=21694554

Family Applications (1)

Application Number Title Priority Date Filing Date
NO940028A NO940028D0 (no) 1993-01-06 1994-01-04 O-aryletere av morfinaner

Country Status (23)

Country Link
EP (1) EP0612730B1 (OSRAM)
JP (1) JP2501298B2 (OSRAM)
KR (1) KR940018094A (OSRAM)
CN (1) CN1097006A (OSRAM)
AT (1) ATE154931T1 (OSRAM)
AU (1) AU681601B2 (OSRAM)
BR (1) BR9400021A (OSRAM)
CA (1) CA2110337A1 (OSRAM)
CZ (1) CZ2294A3 (OSRAM)
DE (1) DE69311887T2 (OSRAM)
DK (1) DK0612730T3 (OSRAM)
ES (1) ES2105061T3 (OSRAM)
FI (1) FI940041L (OSRAM)
GR (1) GR3024891T3 (OSRAM)
HU (2) HUT66061A (OSRAM)
IL (1) IL108247A (OSRAM)
MX (1) MX9400177A (OSRAM)
NO (1) NO940028D0 (OSRAM)
NZ (1) NZ250580A (OSRAM)
PL (1) PL175365B1 (OSRAM)
TW (1) TW264473B (OSRAM)
UY (1) UY23706A1 (OSRAM)
ZA (1) ZA939806B (OSRAM)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9522176D0 (en) * 1995-10-30 1996-01-03 Iaf Biochem Int Morphinan derivatives having neuroprotective activity
EP1384720A1 (en) * 1996-06-13 2004-01-28 SUMIKA FINE CHEMICALS Co., Ltd. Process for drying paroxetine hydrochloride
FR2752163B1 (fr) * 1996-08-12 1998-10-30 Pf Medicament Utilisation de l'efaroxan pour la fabricaton de medicament destine au traitement de la maladie de huntington
GB9706753D0 (en) * 1997-04-03 1997-05-21 Pharmacia & Upjohn Spa Aralkoxy-morphinan derivatives
KR100425881B1 (ko) * 2001-03-14 2004-04-03 고광호 신규한 몰피난 유도체
CN103405431B (zh) * 2002-05-17 2016-04-13 台湾J药品有限公司 阿片和阿片样化合物及其用途
DE10229842A1 (de) * 2002-07-03 2004-02-05 Helmut Prof. Dr. Schmidhammer Morphinanderivate und deren quartäre Ammoniumsalze substituiert in Position 14, Herstellungsverfahren und Verwendung
US20040204862A1 (en) 2003-04-11 2004-10-14 Wainer Irving W. Computer-based model for identification and characterization for non-competitive inhibitors of nicotinic acetylcholine receptors and related ligand-gated ion channel receptors
US8017622B2 (en) 2003-05-16 2011-09-13 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
CN102325776A (zh) * 2009-02-23 2012-01-18 马林克罗特公司 (+)-吗啡喃*季盐及其制备方法
CN103044327B (zh) * 2013-01-07 2014-12-17 苏州立新制药有限公司 一种右美沙芬的制备方法
KR20170052684A (ko) * 2014-09-14 2017-05-12 아바니르 파마슈티컬스, 인코포레이티드 치매에서의 초조함을 치료하기 위한 덱스트로메토르판 화합물 및 퀴니딘을 포함하는 약제학적 조성물
US20160243112A1 (en) * 2015-02-25 2016-08-25 Alkermes, Inc. Treatments for alzheimer's related diseases and disorders
WO2022045301A1 (ja) * 2020-08-28 2022-03-03 日本ケミファ株式会社 新規銅触媒を用いたジアリールエーテル骨格を有するモルヒナン誘導体の製造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI773636A7 (fi) * 1976-12-06 1978-06-07 Hoffmann La Roche Nya fenylderivat
US4113729A (en) * 1976-12-06 1978-09-12 Hoffmann-La Roche Inc. 3-Phenoxymorphinans and derivatives thereof
US4806543A (en) * 1986-11-25 1989-02-21 Board Of Trustees Of The Leland Stanford Junior University Method and compositions for reducing neurotoxic injury

Also Published As

Publication number Publication date
CN1097006A (zh) 1995-01-04
AU5280793A (en) 1994-07-14
FI940041A7 (fi) 1994-07-07
DK0612730T3 (da) 1998-02-02
CZ2294A3 (en) 1994-07-13
BR9400021A (pt) 1994-07-26
HU9400002D0 (en) 1994-05-30
KR940018094A (ko) 1994-08-16
ES2105061T3 (es) 1997-10-16
UY23706A1 (es) 1994-06-05
TW264473B (OSRAM) 1995-12-01
HUT66061A (en) 1994-09-28
IL108247A (en) 1998-02-22
CA2110337A1 (en) 1994-07-07
NZ250580A (en) 1996-07-26
EP0612730A1 (en) 1994-08-31
EP0612730B1 (en) 1997-07-02
FI940041L (fi) 1994-07-07
AU681601B2 (en) 1997-09-04
NO940028D0 (no) 1994-01-04
JP2501298B2 (ja) 1996-05-29
FI940041A0 (fi) 1994-01-05
DE69311887D1 (de) 1997-08-07
MX9400177A (es) 1994-07-29
HU211290A9 (en) 1995-11-28
GR3024891T3 (en) 1998-01-30
IL108247A0 (en) 1994-04-12
DE69311887T2 (de) 1998-01-15
ZA939806B (en) 1994-07-06
ATE154931T1 (de) 1997-07-15
PL301784A1 (en) 1994-07-11
PL175365B1 (pl) 1998-12-31
JPH06316564A (ja) 1994-11-15

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