NO933819D0 - Analysesystemer for neurotrofinaktivitet - Google Patents

Analysesystemer for neurotrofinaktivitet

Info

Publication number
NO933819D0
NO933819D0 NO933819A NO933819A NO933819D0 NO 933819 D0 NO933819 D0 NO 933819D0 NO 933819 A NO933819 A NO 933819A NO 933819 A NO933819 A NO 933819A NO 933819 D0 NO933819 D0 NO 933819D0
Authority
NO
Norway
Prior art keywords
image
systems
neurotrophin
activity analysis
bdnf
Prior art date
Application number
NO933819A
Other languages
English (en)
Other versions
NO933819L (no
Inventor
Stephen P Squinto
David Glass
Thomas H Aldrich
Peter Distephano
Trevor Stitt
Mark E Furth
George D Yancopoulos
Peter C Maison-Pierre
Piotr Masiakowski
Nancy Ip
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of NO933819D0 publication Critical patent/NO933819D0/no
Publication of NO933819L publication Critical patent/NO933819L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82Translation products from oncogenes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475Assays involving growth factors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Oncology (AREA)
  • Toxicology (AREA)
  • Neurosurgery (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Saccharide Compounds (AREA)
NO933819A 1991-04-23 1993-10-22 Analysesystemer for neurotrofinaktivitet NO933819L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US69019991A 1991-04-23 1991-04-23
US73655991A 1991-07-26 1991-07-26
PCT/US1992/003376 WO1992018149A1 (en) 1991-04-23 1992-04-23 Assay systems for neurotrophin activity

Publications (2)

Publication Number Publication Date
NO933819D0 true NO933819D0 (no) 1993-10-22
NO933819L NO933819L (no) 1993-12-20

Family

ID=27104557

Family Applications (1)

Application Number Title Priority Date Filing Date
NO933819A NO933819L (no) 1991-04-23 1993-10-22 Analysesystemer for neurotrofinaktivitet

Country Status (19)

Country Link
EP (2) EP1001024B1 (no)
JP (1) JPH06509413A (no)
AT (2) ATE336576T1 (no)
AU (1) AU676664B2 (no)
CA (1) CA2109100A1 (no)
CZ (1) CZ223793A3 (no)
DE (2) DE69232496T2 (no)
DK (1) DK0589961T3 (no)
ES (1) ES2170056T3 (no)
FI (1) FI934701A (no)
HK (1) HK1024935A1 (no)
HU (1) HUT66051A (no)
IE (1) IE921316A1 (no)
IL (1) IL101661A (no)
NO (1) NO933819L (no)
NZ (1) NZ242468A (no)
PT (1) PT100423A (no)
SK (1) SK116593A3 (no)
WO (1) WO1992018149A1 (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ242813A (en) * 1991-05-21 1996-09-25 Regeneron Pharma Neurotrophin -4 (nt-4), its use as a pharmaceutical, diagnostic kits, chimeric preproproteins, vectors, recombinant nt-4
WO1993025684A1 (en) * 1992-06-12 1993-12-23 Regeneron Pharmaceuticals, Inc. Therapeutic and diagnostic methods based on neurotrophin-4 expression
JPH07246040A (ja) * 1993-07-06 1995-09-26 Takeda Chem Ind Ltd ニューロトロフィン−3遺伝子が不活性化された胚幹細胞および該遺伝子発現不全動物
US5625121A (en) * 1993-09-02 1997-04-29 Bristol-Myers Squibb Company Mice deficient in nerve growth factor receptors encoded by trkB
US5753225A (en) * 1993-12-03 1998-05-19 The Regents Of The University Of California Antibodies that mimic actions of neurotrophins
US6867179B1 (en) 1994-08-31 2005-03-15 Trustees Of Boston University Methods of inducing hair growth and coloration
US6103689A (en) * 1994-08-31 2000-08-15 Trustees Of Boston University Methods of inducing hair growth and coloration
US7196055B2 (en) 1994-08-31 2007-03-27 Trustees Of Boston University Inhibition of apoptosis in keratinocytes by a ligand of p75 nerve growth factor receptor
BR9708390A (pt) * 1996-03-28 2000-01-04 Trustees O Boston University Método para identificar uma substância que altera a pigmentação nos melanócitos epidérmicos de vertebrados, substância que inibe, intensifica ou modula a fosforização da tirosinase mediada pela proteìna c-beta quinase, uso de um agente que modula ou inibe a fosforização de um resìduo de serina ou de treonina mediada pela proteìna c-beta quinase, uso em peptìdeo que especificamente interfere na fosforização de resìduos de serina/treonina mediada pela proteìna c-beta quinase, uso de uma construção de dna ou de um peptìdeo para fabricar um medicamento para diminuir a pigmentação na pela, cabelo, lã ou pelo de vertebrados e uso de uma substância que modula a fosforização da tirosinase mediada pela proteìna c-beta quinase.
EP0890105B1 (en) * 1996-03-29 2006-11-22 The Trustees Of Boston University Methods related to Alzheimer's disease for diagnosis, manufacture of medicaments and screening of substances and beta-amyloid related peptides
GB9807781D0 (en) * 1998-04-09 1998-06-10 Univ Bristol Therapeutic agent
EP2789630A1 (en) 2013-04-09 2014-10-15 EngMab AG Bispecific antibodies against CD3e and ROR1
CA2963692A1 (en) 2014-10-09 2016-04-14 Engmab Ag Bispecific antibodies against cd3epsilon and ror1

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4963481A (en) * 1985-12-18 1990-10-16 Genetics Institute Inc Promoter system
US5231001A (en) * 1991-03-14 1993-07-27 The United States Of America As Represented By The Department Of Health And Human Services Trk tyrosine kinase receptor is the physiological receptor for nerve growth factor
CA2062377A1 (en) * 1991-03-21 1992-09-22 Mariano Barbacid Method for detection of neuroactive substances
US5843749A (en) * 1991-07-26 1998-12-01 Regeneron Pharmaceuticals, Inc. Ehk and Ror tyrosine kinases

Also Published As

Publication number Publication date
ES2170056T3 (es) 2002-08-01
EP0589961B1 (en) 2002-03-20
FI934701A (fi) 1993-12-22
FI934701A0 (fi) 1993-10-25
EP1001024A2 (en) 2000-05-17
HUT66051A (en) 1994-09-28
EP0589961A4 (en) 1994-11-02
CA2109100A1 (en) 1992-10-29
AU676664B2 (en) 1997-03-20
DE69232496D1 (de) 2002-04-25
IL101661A (en) 1998-02-08
EP0589961A1 (en) 1994-04-06
CZ223793A3 (en) 1994-08-17
HU9303012D0 (en) 1994-03-28
IE921316A1 (en) 1992-11-04
NZ242468A (en) 1994-12-22
ATE336576T1 (de) 2006-09-15
NO933819L (no) 1993-12-20
JPH06509413A (ja) 1994-10-20
ATE214733T1 (de) 2002-04-15
EP1001024B1 (en) 2006-08-16
SK116593A3 (en) 1994-11-09
IL101661A0 (en) 1992-12-30
HK1024935A1 (en) 2000-10-27
PT100423A (pt) 1993-08-31
DE69233649D1 (de) 2006-09-28
DE69232496T2 (de) 2002-10-10
WO1992018149A1 (en) 1992-10-29
EP1001024A3 (en) 2004-02-18
AU2014992A (en) 1992-11-17
DK0589961T3 (da) 2002-05-27

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