NO933268L - Fremgangsmaate for fremstilling av protein fra udoedelige celler dyrket in vivo - Google Patents

Fremgangsmaate for fremstilling av protein fra udoedelige celler dyrket in vivo

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Publication number
NO933268L
NO933268L NO93933268A NO933268A NO933268L NO 933268 L NO933268 L NO 933268L NO 93933268 A NO93933268 A NO 93933268A NO 933268 A NO933268 A NO 933268A NO 933268 L NO933268 L NO 933268L
Authority
NO
Norway
Prior art keywords
vivo
immune response
compromised
deadly
procedure
Prior art date
Application number
NO93933268A
Other languages
English (en)
Other versions
NO933268D0 (no
Inventor
David James Graham White
Johan Beyers Van Den Bogaerde
Original Assignee
Imutran Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919105532A external-priority patent/GB9105532D0/en
Application filed by Imutran Ltd filed Critical Imutran Ltd
Publication of NO933268L publication Critical patent/NO933268L/no
Publication of NO933268D0 publication Critical patent/NO933268D0/no

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Antistoffer eller protein av- ledet fra en gitt art kan fremstilles i et utvalgt diskordant beslektet verts- dyr ved dyrkning av en hybridom eller en annen udødelig proteinproduserende cellelinje i vertsdyrets bukhule, der- som både vertsdyrets humorale immun- respons og den cellemedierte immun- respons kompromitteres. Den humorale immunrespons kan kompromitteres kongenitalt; slik at f.eks. C3- manglende dyr kan anvendes. Den celle- medierte immunrespons kompromitteres fortrinnsvis ved administrering av syklosporin A. Dette muliggjør frem- stilling av humanavledete antistoffer in vivo, og tillater generelt oppgra- dering av in vivo-fremstillingsmetoder ved anvendelse av større dyr enn de for tiden vanligvis anvendte mus.
NO933268A 1991-03-15 1993-09-14 Fremgangsmaate for fremstilling av protein fra udoedelige celler dyrket in vivo NO933268D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919105532A GB9105532D0 (en) 1991-03-15 1991-03-15 Antibody production
PCT/GB1992/000459 WO1992016645A1 (en) 1991-03-15 1992-03-16 PROTEIN PRODUCTION FROM IMMORTAL CELLS GROWN $i(IN VIVO)

Publications (2)

Publication Number Publication Date
NO933268L true NO933268L (no) 1993-09-14
NO933268D0 NO933268D0 (no) 1993-09-14

Family

ID=26298594

Family Applications (1)

Application Number Title Priority Date Filing Date
NO933268A NO933268D0 (no) 1991-03-15 1993-09-14 Fremgangsmaate for fremstilling av protein fra udoedelige celler dyrket in vivo

Country Status (1)

Country Link
NO (1) NO933268D0 (no)

Also Published As

Publication number Publication date
NO933268D0 (no) 1993-09-14

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