NO921449L - Karbamater av rapamycin - Google Patents

Karbamater av rapamycin

Info

Publication number
NO921449L
NO921449L NO92921449A NO921449A NO921449L NO 921449 L NO921449 L NO 921449L NO 92921449 A NO92921449 A NO 92921449A NO 921449 A NO921449 A NO 921449A NO 921449 L NO921449 L NO 921449L
Authority
NO
Norway
Prior art keywords
rapamycin
carbamates
Prior art date
Application number
NO92921449A
Other languages
English (en)
Norwegian (no)
Other versions
NO921449D0 (no
Inventor
Wenling Kao
Robert Lewis Vogel
John Henry Musser
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/686,728 external-priority patent/US5118678A/en
Priority claimed from US07/837,048 external-priority patent/US5194447A/en
Application filed by American Home Prod filed Critical American Home Prod
Publication of NO921449D0 publication Critical patent/NO921449D0/no
Publication of NO921449L publication Critical patent/NO921449L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Transplantation (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO92921449A 1991-04-17 1992-04-10 Karbamater av rapamycin NO921449L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/686,728 US5118678A (en) 1991-04-17 1991-04-17 Carbamates of rapamycin
US07/837,048 US5194447A (en) 1992-02-18 1992-02-18 Sulfonylcarbamates of rapamycin

Publications (2)

Publication Number Publication Date
NO921449D0 NO921449D0 (no) 1992-04-10
NO921449L true NO921449L (no) 1992-10-19

Family

ID=27103855

Family Applications (1)

Application Number Title Priority Date Filing Date
NO92921449A NO921449L (no) 1991-04-17 1992-04-10 Karbamater av rapamycin

Country Status (12)

Country Link
EP (1) EP0509795A2 (member.php)
JP (1) JPH05112573A (member.php)
KR (1) KR920019798A (member.php)
AU (1) AU642592B2 (member.php)
CZ (1) CZ117392A3 (member.php)
FI (1) FI921595L (member.php)
HU (1) HU9201254D0 (member.php)
IE (1) IE921249A1 (member.php)
MX (1) MX9201710A (member.php)
NO (1) NO921449L (member.php)
NZ (1) NZ242367A (member.php)
SK (1) SK117392A3 (member.php)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5776943A (en) * 1991-05-14 1998-07-07 American Home Products Corporation Rapamycin metabolites
US5118677A (en) * 1991-05-20 1992-06-02 American Home Products Corporation Amide esters of rapamycin
WO1993018043A1 (en) * 1992-03-05 1993-09-16 American Home Products Corporation Novel rapamycin 42-sulfonates and 42-(n-carboalkoxy)sulfamates useful as immunosuppressive agents
GB9307491D0 (en) * 1993-04-08 1993-06-02 Sandoz Ltd Organic compounds
CH686761A5 (de) 1993-05-27 1996-06-28 Sandoz Ag Galenische Formulierungen.
CA2175215C (en) * 1993-11-19 2008-06-03 Yat Sun Or Semisynthetic analogs of rapamycin (macrolides) being immunomodulators
US5527907A (en) * 1993-11-19 1996-06-18 Abbott Laboratories Macrolide immunomodulators
US5362718A (en) 1994-04-18 1994-11-08 American Home Products Corporation Rapamycin hydroxyesters
EP2298311B1 (en) 1999-01-13 2012-05-09 Bayer HealthCare LLC w-Carboxy aryl substituted diphenyl ureas as p38 kinase inhibitors
US8124630B2 (en) 1999-01-13 2012-02-28 Bayer Healthcare Llc ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
DE60012192T2 (de) * 1999-08-18 2005-09-08 Wyeth Wasserlösliche sdz-rad ester
ES2425739T3 (es) 2002-02-11 2013-10-17 Bayer Healthcare Llc Sorafenib-tosilato para el tratamiento de enfermedades caracterizadas por angiogénesis anormal
US7557129B2 (en) 2003-02-28 2009-07-07 Bayer Healthcare Llc Cyanopyridine derivatives useful in the treatment of cancer and other disorders
CA2526636C (en) 2003-05-20 2012-10-02 Bayer Pharmaceuticals Corporation Diaryl ureas for diseases mediated by pdgfr
BR122016015715B8 (pt) 2003-07-23 2021-05-25 Bayer Healthcare Llc composições farmacêuticas de metilamida de ácido 4[4-[3-(4-cloro-3-trifluorometilfenil)-ureido]-3-fluorofenóxi)-piridina-2-carboxílico
WO2005042567A1 (en) * 2003-11-03 2005-05-12 Altachem Pharma Ltd. Rapamycin peptides conjugates: synthesis and uses thereof
US8021849B2 (en) 2004-11-05 2011-09-20 Siemens Healthcare Diagnostics Inc. Methods and kits for the determination of sirolimus in a sample
CA2602010A1 (en) 2005-03-07 2006-09-14 Wyeth Oxepane isomer of 42-o-(2-hydroxy)ethyl-rapamycin
US7189582B2 (en) 2005-04-27 2007-03-13 Dade Behring Inc. Compositions and methods for detection of sirolimus
CN113660983A (zh) * 2019-01-25 2021-11-16 诺瑟拉有限公司 氨基甲酸酯衍生物及其用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4885171A (en) * 1978-11-03 1989-12-05 American Home Products Corporation Use of rapamycin in treatment of certain tumors
US4316885A (en) * 1980-08-25 1982-02-23 Ayerst, Mckenna And Harrison, Inc. Acyl derivatives of rapamycin
US4650803A (en) * 1985-12-06 1987-03-17 University Of Kansas Prodrugs of rapamycin
EP0487593A1 (en) * 1989-08-18 1992-06-03 FISONS plc Macrocyclic compounds
PT98990A (pt) * 1990-09-19 1992-08-31 American Home Prod Processo para a preparacao de esteres de acidos carboxilicos de rapamicina
US5118677A (en) * 1991-05-20 1992-06-02 American Home Products Corporation Amide esters of rapamycin

Also Published As

Publication number Publication date
NZ242367A (en) 1994-07-26
KR920019798A (ko) 1992-11-20
AU642592B2 (en) 1993-10-21
EP0509795A2 (en) 1992-10-21
EP0509795A3 (member.php) 1994-03-23
SK117392A3 (en) 1995-04-12
HU9201254D0 (en) 1992-07-28
JPH05112573A (ja) 1993-05-07
FI921595A0 (fi) 1992-04-10
MX9201710A (es) 1993-01-01
CZ117392A3 (en) 1993-09-15
NO921449D0 (no) 1992-04-10
FI921595A7 (fi) 1992-10-18
IE921249A1 (en) 1992-10-21
AU1488092A (en) 1992-10-22
FI921595L (fi) 1992-10-18

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