NO913543L - Fremgangsmaate for fremstilling av 3-(1h-indazol-3-yl)-4-pyridinaminer og mellomprodukter, og anvendelse som medikamenter. - Google Patents

Fremgangsmaate for fremstilling av 3-(1h-indazol-3-yl)-4-pyridinaminer og mellomprodukter, og anvendelse som medikamenter.

Info

Publication number
NO913543L
NO913543L NO91913543A NO913543A NO913543L NO 913543 L NO913543 L NO 913543L NO 91913543 A NO91913543 A NO 91913543A NO 913543 A NO913543 A NO 913543A NO 913543 L NO913543 L NO 913543L
Authority
NO
Norway
Prior art keywords
hydrogen
loweralkyl
pyridinamines
indazol
intermediates
Prior art date
Application number
NO91913543A
Other languages
English (en)
Norwegian (no)
Other versions
NO913543D0 (no
Inventor
Richard Charles Effland
Joseph Thomas Klein
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of NO913543D0 publication Critical patent/NO913543D0/no
Publication of NO913543L publication Critical patent/NO913543L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO91913543A 1990-09-10 1991-09-09 Fremgangsmaate for fremstilling av 3-(1h-indazol-3-yl)-4-pyridinaminer og mellomprodukter, og anvendelse som medikamenter. NO913543L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/579,751 US5051430A (en) 1990-09-10 1990-09-10 3-(1H-indazol-3-yl)-4-pyridinamines

Publications (2)

Publication Number Publication Date
NO913543D0 NO913543D0 (no) 1991-09-09
NO913543L true NO913543L (no) 1992-03-11

Family

ID=24318208

Family Applications (1)

Application Number Title Priority Date Filing Date
NO91913543A NO913543L (no) 1990-09-10 1991-09-09 Fremgangsmaate for fremstilling av 3-(1h-indazol-3-yl)-4-pyridinaminer og mellomprodukter, og anvendelse som medikamenter.

Country Status (20)

Country Link
US (1) US5051430A (de)
EP (1) EP0475352B1 (de)
JP (1) JP3042915B2 (de)
KR (1) KR100203236B1 (de)
AT (1) ATE123493T1 (de)
AU (1) AU640590B2 (de)
CA (1) CA2050875C (de)
CZ (1) CZ280883B6 (de)
DE (1) DE69110219T2 (de)
DK (1) DK0475352T3 (de)
ES (1) ES2074618T3 (de)
FI (1) FI914219A (de)
HU (1) HUT59126A (de)
IE (1) IE67442B1 (de)
IL (1) IL99434A (de)
NO (1) NO913543L (de)
NZ (1) NZ239692A (de)
PL (1) PL295728A1 (de)
PT (1) PT98911B (de)
ZA (1) ZA917141B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL288420A1 (en) * 1989-12-27 1992-06-15 Hoechst Roussel Pharma Method of obtaining derivatives of aminopyridinylomethanoles and aminomethylpyridine amines
US7211594B2 (en) 2000-07-31 2007-05-01 Signal Pharmaceuticals, Llc Indazole compounds and compositions thereof as JNK inhibitors and for the treatment of diseases associated therewith
US6897231B2 (en) 2000-07-31 2005-05-24 Signal Pharmaceuticals, Inc. Indazole derivatives as JNK inhibitors and compositions and methods related thereto
CN1300116C (zh) * 2001-04-16 2007-02-14 卫材株式会社 1h－吲唑化合物
EP1720855A4 (de) * 2004-03-02 2008-12-17 Smithkline Beecham Corp Hemmer der akt aktivität
US7812045B2 (en) * 2005-03-30 2010-10-12 Daewoong Pharmaceutical Co., Ltd. Antifungal triazole derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU198036B (en) * 1983-08-22 1989-07-28 Hoechst Roussel Pharma Process for production of derivatives of 3-piperidil-/1h/-indasole and medical preparatives containing them

Also Published As

Publication number Publication date
PT98911A (pt) 1992-07-31
ZA917141B (en) 1992-04-29
CS277691A3 (en) 1992-04-15
IE913157A1 (en) 1992-03-11
IL99434A (en) 1995-08-31
PT98911B (pt) 1999-02-26
US5051430A (en) 1991-09-24
EP0475352A1 (de) 1992-03-18
KR920006346A (ko) 1992-04-27
FI914219A0 (fi) 1991-09-06
HUT59126A (en) 1992-04-28
CZ280883B6 (cs) 1996-04-17
CA2050875C (en) 2002-07-16
JPH04247079A (ja) 1992-09-03
KR100203236B1 (ko) 1999-06-15
ES2074618T3 (es) 1995-09-16
IL99434A0 (en) 1992-08-18
DE69110219T2 (de) 1995-11-09
EP0475352B1 (de) 1995-06-07
NZ239692A (en) 1994-01-26
CA2050875A1 (en) 1992-03-11
AU640590B2 (en) 1993-08-26
AU8371691A (en) 1992-03-12
ATE123493T1 (de) 1995-06-15
IE67442B1 (en) 1996-04-03
PL295728A1 (en) 1993-05-04
FI914219A (fi) 1992-03-11
HU912901D0 (en) 1992-01-28
DE69110219D1 (de) 1995-07-13
JP3042915B2 (ja) 2000-05-22
DK0475352T3 (da) 1995-10-16
NO913543D0 (no) 1991-09-09

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