NO911174L - Kermesbaer antiviralt protein (pap)-monoklonalt antistoffkonjugat. - Google Patents

Kermesbaer antiviralt protein (pap)-monoklonalt antistoffkonjugat.

Info

Publication number
NO911174L
NO911174L NO91911174A NO911174A NO911174L NO 911174 L NO911174 L NO 911174L NO 91911174 A NO91911174 A NO 91911174A NO 911174 A NO911174 A NO 911174A NO 911174 L NO911174 L NO 911174L
Authority
NO
Norway
Prior art keywords
pap
monoclonal antibody
kermesbaer
antiviral protein
antibody conjugate
Prior art date
Application number
NO91911174A
Other languages
English (en)
Other versions
NO911174D0 (no
Inventor
Fatih M Uckun
Joyce M Zarling
Original Assignee
Univ Minnesota
Oncogen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Minnesota, Oncogen filed Critical Univ Minnesota
Publication of NO911174D0 publication Critical patent/NO911174D0/no
Publication of NO911174L publication Critical patent/NO911174L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6849—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
    • A61K47/6817—Toxins
    • A61K47/6819—Plant toxins
    • A61K47/6825—Ribosomal inhibitory proteins, i.e. RIP-I or RIP-II, e.g. Pap, gelonin or dianthin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Botany (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Kermesbær antiviralt protein (PAP)- monoklonale antistoffkonjugater som er istand til å inhibere virusreplikasjon i pattedyrceller uten detekterbar cytotok- sisitet er fremskaffet.
NO91911174A 1989-07-25 1991-03-22 Kermesbaer antiviralt protein (pap)-monoklonalt antistoffkonjugat. NO911174L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38531489A 1989-07-25 1989-07-25
US50352290A 1990-03-30 1990-03-30
PCT/US1990/003921 WO1991001145A1 (en) 1989-07-25 1990-07-12 Pokeweed antiviral protein - monoclonal antibody conjugates

Publications (2)

Publication Number Publication Date
NO911174D0 NO911174D0 (no) 1991-03-22
NO911174L true NO911174L (no) 1991-05-24

Family

ID=27010961

Family Applications (1)

Application Number Title Priority Date Filing Date
NO91911174A NO911174L (no) 1989-07-25 1991-03-22 Kermesbaer antiviralt protein (pap)-monoklonalt antistoffkonjugat.

Country Status (17)

Country Link
EP (1) EP0441917B1 (no)
JP (1) JP3109678B2 (no)
KR (1) KR920700698A (no)
AT (1) ATE137410T1 (no)
AU (1) AU631674B2 (no)
CA (1) CA2037900C (no)
DE (1) DE69026812T2 (no)
DK (1) DK0441917T3 (no)
ES (1) ES2087158T3 (no)
FI (1) FI911447A0 (no)
GR (1) GR1002180B (no)
IE (1) IE74143B1 (no)
IL (1) IL95134A (no)
NO (1) NO911174L (no)
NZ (1) NZ234607A (no)
PT (1) PT94789B (no)
WO (1) WO1991001145A1 (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0425604U (no) * 1990-06-27 1992-02-28
GB9217124D0 (en) * 1992-08-13 1992-09-23 Antisoma Ltd Medical treatment
US6576236B1 (en) * 1994-07-01 2003-06-10 Dana Farber Cancer Institute Methods for stimulating T cell responses by manipulating a common cytokine receptor γ chain
US5919457A (en) * 1996-01-11 1999-07-06 Regents Of The University Of Minnesota TXU-5/B53-PAP antiviral biotherapeutic agent for the treatment of AIDS
KR101972836B1 (ko) 2011-04-12 2019-04-29 노보 노르디스크 에이/에스 이중 아실화된 ｇｌｐ-1 유도체

Also Published As

Publication number Publication date
DK0441917T3 (da) 1996-09-16
PT94789A (pt) 1991-03-20
IL95134A (en) 1996-01-31
IE74143B1 (en) 1997-07-02
EP0441917A1 (en) 1991-08-21
DE69026812T2 (de) 1996-11-28
NO911174D0 (no) 1991-03-22
ES2087158T3 (es) 1996-07-16
FI911447A0 (fi) 1991-03-25
NZ234607A (en) 1992-10-28
WO1991001145A1 (en) 1991-02-07
CA2037900C (en) 1999-11-16
PT94789B (pt) 1997-04-30
GR1002180B (en) 1996-03-11
AU631674B2 (en) 1992-12-03
AU6140590A (en) 1991-02-22
CA2037900A1 (en) 1991-01-26
DE69026812D1 (de) 1996-06-05
IL95134A0 (en) 1991-06-10
IE902593A1 (en) 1991-02-27
GR900100550A (el) 1991-12-10
JPH04502625A (ja) 1992-05-14
ATE137410T1 (de) 1996-05-15
KR920700698A (ko) 1992-08-10
JP3109678B2 (ja) 2000-11-20
EP0441917B1 (en) 1996-05-01

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