NO882791L - Fremgangsmaate for fremstilling av enkeltkjede urokinase. - Google Patents

Fremgangsmaate for fremstilling av enkeltkjede urokinase.

Info

Publication number
NO882791L
NO882791L NO88882791A NO882791A NO882791L NO 882791 L NO882791 L NO 882791L NO 88882791 A NO88882791 A NO 88882791A NO 882791 A NO882791 A NO 882791A NO 882791 L NO882791 L NO 882791L
Authority
NO
Norway
Prior art keywords
upa
human
dna
promoter
scu
Prior art date
Application number
NO88882791A
Other languages
English (en)
Norwegian (no)
Other versions
NO882791D0 (no
Inventor
Giovanni Cassani
Marialuisa Nolli
Frederica Maria Robbiati
Angelo Corti
Francesco Blasi
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878718877A external-priority patent/GB8718877D0/en
Application filed by Lepetit Spa filed Critical Lepetit Spa
Publication of NO882791D0 publication Critical patent/NO882791D0/no
Publication of NO882791L publication Critical patent/NO882791L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6456Plasminogen activators
    • C12N9/6462Plasminogen activators u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21073Serine endopeptidases (3.4.21) u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
NO88882791A 1987-08-10 1988-06-23 Fremgangsmaate for fremstilling av enkeltkjede urokinase. NO882791L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878718877A GB8718877D0 (en) 1987-08-10 1987-08-10 Preparing single chain urokinase
US17333788A 1988-03-24 1988-03-24

Publications (2)

Publication Number Publication Date
NO882791D0 NO882791D0 (no) 1988-06-23
NO882791L true NO882791L (no) 1989-02-13

Family

ID=26292587

Family Applications (1)

Application Number Title Priority Date Filing Date
NO88882791A NO882791L (no) 1987-08-10 1988-06-23 Fremgangsmaate for fremstilling av enkeltkjede urokinase.

Country Status (12)

Country Link
EP (1) EP0303028A1 (de)
JP (1) JPH01132378A (de)
KR (1) KR890003950A (de)
CN (1) CN1033289A (de)
AU (1) AU1834488A (de)
DK (1) DK340488A (de)
FI (1) FI882977A (de)
HU (1) HU208712B (de)
IL (1) IL86801A0 (de)
NO (1) NO882791L (de)
NZ (1) NZ225143A (de)
PT (1) PT87836A (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE901849A1 (en) * 1989-07-19 1991-06-19 Gruenenthal Gmbh Plasmids, their preparation and their use in the manufacture¹of a plasminogen activator
CN1062016C (zh) * 1996-09-27 2001-02-14 中国人民解放军军事医学科学院生物工程研究所 重组人糖基化尿激酶原的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3585097D1 (de) * 1984-02-27 1992-02-20 Green Cross Corp Herstellung menschlicher urokinase.
JPS62149625A (ja) * 1985-12-25 1987-07-03 Green Cross Corp:The 生理活性物質の製造方法

Also Published As

Publication number Publication date
AU1834488A (en) 1989-02-16
EP0303028A1 (de) 1989-02-15
NZ225143A (en) 1991-01-29
DK340488D0 (da) 1988-06-21
KR890003950A (ko) 1989-04-19
PT87836A (pt) 1989-06-30
FI882977A0 (fi) 1988-06-22
HUT47324A (en) 1989-02-28
JPH01132378A (ja) 1989-05-24
CN1033289A (zh) 1989-06-07
DK340488A (da) 1989-02-11
NO882791D0 (no) 1988-06-23
IL86801A0 (en) 1988-11-30
FI882977A (fi) 1989-02-11
HU208712B (en) 1993-12-28

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