NO882469L - Fremgangsmaate for produksjon av proteiner ved bruk av induserbare ekspresjonssystemer i genetisk modifiserte eukaryote vertsceller formert in vivo. - Google Patents

Fremgangsmaate for produksjon av proteiner ved bruk av induserbare ekspresjonssystemer i genetisk modifiserte eukaryote vertsceller formert in vivo.

Info

Publication number
NO882469L
NO882469L NO882469A NO882469A NO882469L NO 882469 L NO882469 L NO 882469L NO 882469 A NO882469 A NO 882469A NO 882469 A NO882469 A NO 882469A NO 882469 L NO882469 L NO 882469L
Authority
NO
Norway
Prior art keywords
cells
gene
plasmid
tumor
promoter
Prior art date
Application number
NO882469A
Other languages
English (en)
Norwegian (no)
Other versions
NO882469D0 (no
Inventor
Peter Bromley
Michel Dreano
Michel Fischbach
Xavier Fouillet
Prudent Padieu
Richard Voellmy
Original Assignee
Battelle Memorial Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Battelle Memorial Institute filed Critical Battelle Memorial Institute
Publication of NO882469D0 publication Critical patent/NO882469D0/no
Publication of NO882469L publication Critical patent/NO882469L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/61Growth hormone [GH], i.e. somatotropin
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • A01K67/0271Chimeric vertebrates, e.g. comprising exogenous cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/001Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
    • C12N2830/002Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/80Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/85Vector systems having a special element relevant for transcription from vertebrates mammalian

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Environmental Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Animal Husbandry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO882469A 1986-10-15 1988-06-03 Fremgangsmaate for produksjon av proteiner ved bruk av induserbare ekspresjonssystemer i genetisk modifiserte eukaryote vertsceller formert in vivo. NO882469L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP86810455A EP0263908B1 (en) 1986-10-15 1986-10-15 Method for the production of proteins by means of inducible expression systems in genetically modified eukaryotic host-cells multiplicated in-vivo
PCT/EP1987/000599 WO1988002778A1 (en) 1986-10-15 1987-10-12 Method for the production of proteins by means of inducible expression systems in genetically modified eukaryotic host-cells multiplicated in-vivo

Publications (2)

Publication Number Publication Date
NO882469D0 NO882469D0 (no) 1988-06-03
NO882469L true NO882469L (no) 1988-06-03

Family

ID=8196470

Family Applications (1)

Application Number Title Priority Date Filing Date
NO882469A NO882469L (no) 1986-10-15 1988-06-03 Fremgangsmaate for produksjon av proteiner ved bruk av induserbare ekspresjonssystemer i genetisk modifiserte eukaryote vertsceller formert in vivo.

Country Status (12)

Country Link
US (1) US5614381A (enExample)
EP (2) EP0263908B1 (enExample)
JP (1) JP2509271B2 (enExample)
AT (1) ATE67787T1 (enExample)
AU (1) AU612607B2 (enExample)
CA (1) CA1319631C (enExample)
DE (1) DE3681738D1 (enExample)
DK (1) DK320888D0 (enExample)
ES (1) ES2038602T3 (enExample)
NO (1) NO882469L (enExample)
WO (1) WO1988002778A1 (enExample)
ZA (1) ZA877656B (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL85728A (en) * 1987-03-25 1993-01-14 Bio Mega Inc Fluorine containing atrial natriuretic peptides, their preparation and pharmaceutical compositions containing them
JP2796547B2 (ja) * 1987-09-11 1998-09-10 ジェネンテク,インコーポレイテッド 組換え細胞培養中でのポリペプチド発現の増大法
EP0390857A4 (en) * 1987-12-15 1991-04-17 The Trustees Of Princeton University Transgenic testing systems for mutagens and carcinogens
ZA892518B (en) * 1988-04-08 1989-12-27 Intracel Corp Method for the in-vivo production and testing of proteins by recombinant gene expression in selected host-cells
WO1990001543A1 (fr) * 1988-07-29 1990-02-22 Intracel Corporation Procede d'expression genetique de proteines heterologues par des cellules transfectees in vivo
GB8928884D0 (en) * 1989-12-21 1990-02-28 Feldmann Marc Transformed cell lines
GB9003791D0 (en) * 1990-02-20 1990-04-18 Ludwig Inst Cancer Res Transgenic animals,cell lines therefrom,and their use
US5866759A (en) * 1991-02-20 1999-02-02 Ludwig Institute For Cancer Research Transgenic mice expressing TSSV40 large T antigen
US5877398A (en) * 1993-01-29 1999-03-02 University Of British Columbia Biological systems incorporating stress-inducible genes and reporter constructs for environmental biomonitoring and toxicology
JP2001501458A (ja) 1996-08-15 2001-02-06 アメリカ合衆国 ヒートショックタンパク質プロモーターと局部加熱との組合せを利用した遺伝子発現の場所的及び時期的制御
IT1294450B1 (it) * 1997-08-28 1999-03-25 Consiglio Nazionale Ricerche Animali transgenici per lo studio di agenti tossici chimici fisici o biologici
US7098191B2 (en) * 1997-11-03 2006-08-29 The Arizona Board Of Reagents Hyperthermic inducible expression vectors for gene therapy and methods of use thereof
US6709858B1 (en) * 1997-11-03 2004-03-23 The Arizona Board Of Regents On Behalf Of The University Of Arizona Hyperthermic inducible expression vectors for gene therapy and methods of use thereof
US7279565B2 (en) * 1998-05-05 2007-10-09 Richard Voellmy Molecular regulatory circuits to achieve sustained activation of genes of interest by a single stress
AUPQ233799A0 (en) 1999-08-19 1999-09-09 Minister For Agriculture, Minister For Land And Water Conservation For And On Behalf Of The State Of New South Wales Recombinant sub-unit vaccine
US20030044398A1 (en) * 2001-03-20 2003-03-06 Robl James M. Methods for producing antibodies in mammals
CA2349506C (en) * 2001-06-14 2009-12-08 Duke University A method for selective expression of therapeutic genes by hyperthermia
WO2006037215A1 (en) * 2004-10-04 2006-04-13 National Research Council Of Canada Expression system, components thereof and methods of use
US7935788B2 (en) * 2004-10-04 2011-05-03 National Research Council Of Canada Reverse cumate repressor mutant

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4399216A (en) * 1980-02-25 1983-08-16 The Trustees Of Columbia University Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
JPS5729294A (en) * 1980-07-30 1982-02-17 Hayashibara Biochem Lab Inc Preparation of human insulin
JPS5852634B2 (ja) * 1980-12-05 1983-11-24 株式会社林原生物化学研究所 ウロキナ−ゼの製造法
IE56720B1 (en) * 1983-02-07 1991-11-20 Battelle Memorial Institute Methods and compositions for expression of competent eukaryotic gene products
WO1987005935A1 (en) * 1986-04-04 1987-10-08 Battelle Memorial Institute At Columbus, Ohio Gene Methods and compositions for expression of competent eukaryotic gene products
AU8108687A (en) * 1986-09-30 1988-04-21 Smithkline Beckman Corporation Cell transfection
PT87363B (pt) * 1987-05-01 1993-11-30 Gen Hospital Corp Metodo para alterar a concentracao de um produto genetico

Also Published As

Publication number Publication date
WO1988002778A1 (en) 1988-04-21
US5614381A (en) 1997-03-25
AU612607B2 (en) 1991-07-18
DE3681738D1 (enExample) 1991-10-31
EP0263908B1 (en) 1991-09-25
EP0263908A1 (en) 1988-04-20
NO882469D0 (no) 1988-06-03
JP2509271B2 (ja) 1996-06-19
ATE67787T1 (de) 1991-10-15
DK320888A (da) 1988-06-13
AU8078487A (en) 1988-05-06
EP0285642A1 (en) 1988-10-12
JPH01501439A (ja) 1989-05-25
ES2038602T3 (es) 1993-08-01
ZA877656B (en) 1988-04-18
DK320888D0 (da) 1988-06-13
CA1319631C (en) 1993-06-29

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