IT1294450B1 - Animali transgenici per lo studio di agenti tossici chimici fisici o biologici - Google Patents

Animali transgenici per lo studio di agenti tossici chimici fisici o biologici

Info

Publication number
IT1294450B1
IT1294450B1 ITMI971972A IT1294450B1 IT 1294450 B1 IT1294450 B1 IT 1294450B1 IT MI971972 A ITMI971972 A IT MI971972A IT 1294450 B1 IT1294450 B1 IT 1294450B1
Authority
IT
Italy
Prior art keywords
study
physical
transgenic animals
toxic agents
biological chemical
Prior art date
Application number
Other languages
English (en)
Inventor
Maria Grazia Sacco
Luigi Zecca
Peter Bromley
Romeo Roncucci
Libero A Clerici
Paolo Vezzoni
Original Assignee
Consiglio Nazionale Ricerche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consiglio Nazionale Ricerche filed Critical Consiglio Nazionale Ricerche
Priority to ITMI971972 priority Critical patent/IT1294450B1/it
Priority to AU86469/98A priority patent/AU8646998A/en
Priority to CA002302220A priority patent/CA2302220A1/en
Priority to JP2000508783A priority patent/JP2001514848A/ja
Priority to PCT/IT1998/000231 priority patent/WO1999011772A1/en
Priority to EP98937782A priority patent/EP1029037A1/en
Publication of ITMI971972A1 publication Critical patent/ITMI971972A1/it
Application granted granted Critical
Publication of IT1294450B1 publication Critical patent/IT1294450B1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A01K67/0278—Knock-in vertebrates, e.g. humanised vertebrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00—Modified animals
    • A01K2207/15—Humanized animals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/20—Animal model comprising regulated expression system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0393—Animal model comprising a reporter system for screening tests

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Environmental Sciences (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Plant Substances (AREA)
ITMI971972 1997-08-28 1997-08-28 Animali transgenici per lo studio di agenti tossici chimici fisici o biologici IT1294450B1 (it)

Priority Applications (6)

Application Number Priority Date Filing Date Title
ITMI971972 IT1294450B1 (it) 1997-08-28 1997-08-28 Animali transgenici per lo studio di agenti tossici chimici fisici o biologici
AU86469/98A AU8646998A (en) 1997-08-28 1998-08-11 Transgenic animals for the study of biological, physical and chemical toxic agents
CA002302220A CA2302220A1 (en) 1997-08-28 1998-08-11 Transgenic animals for the study of biological, physical and chemical toxic agents
JP2000508783A JP2001514848A (ja) 1997-08-28 1998-08-11 生物的、物理的ならびに化学的な毒性因子の研究用トランスジェニック動物
PCT/IT1998/000231 WO1999011772A1 (en) 1997-08-28 1998-08-11 Transgenic animals for the study of biological, physical and chemical toxic agents
EP98937782A EP1029037A1 (en) 1997-08-28 1998-08-11 Transgenic animals bearing stress sensitive regulatory sequences

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI971972 IT1294450B1 (it) 1997-08-28 1997-08-28 Animali transgenici per lo studio di agenti tossici chimici fisici o biologici

Publications (2)

Publication Number Publication Date
ITMI971972A1 ITMI971972A1 (it) 1999-02-28
IT1294450B1 true IT1294450B1 (it) 1999-03-25

Family

ID=11377792

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI971972 IT1294450B1 (it) 1997-08-28 1997-08-28 Animali transgenici per lo studio di agenti tossici chimici fisici o biologici

Country Status (6)

Country Link
EP (1) EP1029037A1 (it)
JP (1) JP2001514848A (it)
AU (1) AU8646998A (it)
CA (1) CA2302220A1 (it)
IT (1) IT1294450B1 (it)
WO (1) WO1999011772A1 (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1141359B1 (en) 1998-12-17 2006-10-04 Xenogen Corporation Non-invasive evaluation of physiological response in a mammal
ITTO20020729A1 (it) * 2002-08-14 2004-02-15 Consorzio Interuniversitario Per Le Biotecnologie Cellule di mammifero non umano geneticamente modificate, procedimento per la loro produzione e utilizzo in test di tossicita'.
DE102007035238A1 (de) 2007-07-27 2009-01-29 Christian-Albrechts-Universität Zu Kiel Biologisches Effektmonitoring mittels transgener Hydra

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0263908B1 (en) * 1986-10-15 1991-09-25 Battelle Memorial Institute Method for the production of proteins by means of inducible expression systems in genetically modified eukaryotic host-cells multiplicated in-vivo
ZA892518B (en) * 1988-04-08 1989-12-27 Intracel Corp Method for the in-vivo production and testing of proteins by recombinant gene expression in selected host-cells
CA2088379A1 (en) * 1993-01-29 1994-07-30 University Of British Columbia Biological systems incorporating stress-inducible genes and reporter constructs for environmental biomonitoring and toxicology
AU5619298A (en) * 1997-01-03 1998-07-31 University Technology Corporation Beta-amyloid toxicity

Also Published As

Publication number Publication date
JP2001514848A (ja) 2001-09-18
WO1999011772A1 (en) 1999-03-11
ITMI971972A1 (it) 1999-02-28
EP1029037A1 (en) 2000-08-23
CA2302220A1 (en) 1999-03-11
AU8646998A (en) 1999-03-22

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Legal Events

Date Code Title Description
0001 Granted