NO881610L - Antistoff og fremgangsmaate for dets fremstilling og anvendelse, saerlig for diagnose. - Google Patents
Antistoff og fremgangsmaate for dets fremstilling og anvendelse, saerlig for diagnose.Info
- Publication number
- NO881610L NO881610L NO881610A NO881610A NO881610L NO 881610 L NO881610 L NO 881610L NO 881610 A NO881610 A NO 881610A NO 881610 A NO881610 A NO 881610A NO 881610 L NO881610 L NO 881610L
- Authority
- NO
- Norway
- Prior art keywords
- binder
- antibody
- animal
- hybridomas
- monoclonal antibody
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims description 35
- 238000004519 manufacturing process Methods 0.000 title claims description 11
- 238000003745 diagnosis Methods 0.000 title claims description 6
- 102000011409 Transcobalamins Human genes 0.000 claims description 44
- 108010023603 Transcobalamins Proteins 0.000 claims description 44
- 210000004408 hybridoma Anatomy 0.000 claims description 36
- 210000004027 cell Anatomy 0.000 claims description 30
- 238000003556 assay Methods 0.000 claims description 25
- 239000011230 binding agent Substances 0.000 claims description 22
- 239000012228 culture supernatant Substances 0.000 claims description 19
- 238000012216 screening Methods 0.000 claims description 19
- 238000003018 immunoassay Methods 0.000 claims description 16
- 241001465754 Metazoa Species 0.000 claims description 15
- 238000009739 binding Methods 0.000 claims description 14
- 238000002415 sodium dodecyl sulfate polyacrylamide gel electrophoresis Methods 0.000 claims description 12
- 239000007790 solid phase Substances 0.000 claims description 12
- 206010028980 Neoplasm Diseases 0.000 claims description 11
- 201000011510 cancer Diseases 0.000 claims description 10
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- 210000004798 organs belonging to the digestive system Anatomy 0.000 claims description 4
- 238000001514 detection method Methods 0.000 claims description 3
- 239000003446 ligand Substances 0.000 claims description 2
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- FDJOLVPMNUYSCM-WZHZPDAFSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+3].N#[C-].N([C@@H]([C@]1(C)[N-]\C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C(\C)/C1=N/C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C\C1=N\C([C@H](C1(C)C)CCC(N)=O)=C/1C)[C@@H]2CC(N)=O)=C\1[C@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H](N2C3=CC(C)=C(C)C=C3N=C2)O[C@@H]1CO FDJOLVPMNUYSCM-WZHZPDAFSA-L 0.000 description 4
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- NHBKXEKEPDILRR-UHFFFAOYSA-N 2,3-bis(butanoylsulfanyl)propyl butanoate Chemical compound CCCC(=O)OCC(SC(=O)CCC)CSC(=O)CCC NHBKXEKEPDILRR-UHFFFAOYSA-N 0.000 description 3
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- 229960003495 thiamine Drugs 0.000 description 1
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 description 1
- RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3046—Stomach, Intestines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62093233A JPS63258897A (ja) | 1987-04-17 | 1987-04-17 | 抗ｒ−バインダモノクロナ−ル抗体とその製法および用途 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO881610D0 NO881610D0 (no) | 1988-04-14 |
| NO881610L true NO881610L (no) | 1988-10-18 |
Family
ID=14076818
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO881610A NO881610L (no) | 1987-04-17 | 1988-04-14 | Antistoff og fremgangsmaate for dets fremstilling og anvendelse, saerlig for diagnose. |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0287012A3 (fr) |
| JP (1) | JPS63258897A (fr) |
| DK (1) | DK207488A (fr) |
| FI (1) | FI881631A (fr) |
| NO (1) | NO881610L (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7496411B2 (ja) * | 2019-08-09 | 2024-06-06 | シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレイテッド | 抗ブタｔｃｎ１モノクローナル抗体ならびにその作製方法および使用方法 |
-
1987
- 1987-04-17 JP JP62093233A patent/JPS63258897A/ja active Pending
-
1988
- 1988-04-07 FI FI881631A patent/FI881631A/fi not_active Application Discontinuation
- 1988-04-11 EP EP88105722A patent/EP0287012A3/fr not_active Withdrawn
- 1988-04-14 NO NO881610A patent/NO881610L/no unknown
- 1988-04-15 DK DK207488A patent/DK207488A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0287012A2 (fr) | 1988-10-19 |
| EP0287012A3 (fr) | 1990-01-10 |
| DK207488D0 (da) | 1988-04-15 |
| FI881631A0 (fi) | 1988-04-07 |
| FI881631A (fi) | 1988-10-18 |
| DK207488A (da) | 1988-10-18 |
| JPS63258897A (ja) | 1988-10-26 |
| NO881610D0 (no) | 1988-04-14 |
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