NO875299L - Insulinpreparat for ikke-paranteral administrasjon. - Google Patents
Insulinpreparat for ikke-paranteral administrasjon.Info
- Publication number
- NO875299L NO875299L NO875299A NO875299A NO875299L NO 875299 L NO875299 L NO 875299L NO 875299 A NO875299 A NO 875299A NO 875299 A NO875299 A NO 875299A NO 875299 L NO875299 L NO 875299L
- Authority
- NO
- Norway
- Prior art keywords
- pct
- insulin
- insulin preparation
- sec
- possibly
- Prior art date
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title abstract 8
- 102000004877 Insulin Human genes 0.000 title abstract 5
- 108090001061 Insulin Proteins 0.000 title abstract 5
- 229940125396 insulin Drugs 0.000 title abstract 4
- 238000002360 preparation method Methods 0.000 title abstract 2
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000004026 insulin derivative Substances 0.000 abstract 1
- 239000000178 monomer Substances 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 238000001179 sorption measurement Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Otolaryngology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK179286A DK179286D0 (da) | 1986-04-18 | 1986-04-18 | Insulinpraeparat |
| PCT/DK1987/000038 WO1987006137A1 (en) | 1986-04-18 | 1987-04-14 | An insulin preparation for non-parenteral administration |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO875299D0 NO875299D0 (no) | 1987-12-17 |
| NO875299L true NO875299L (no) | 1987-12-17 |
Family
ID=8108089
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO875299A NO875299L (no) | 1986-04-18 | 1987-12-17 | Insulinpreparat for ikke-paranteral administrasjon. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5053389A (da) |
| EP (1) | EP0267208B1 (da) |
| JP (1) | JPH01500116A (da) |
| AT (1) | ATE66614T1 (da) |
| AU (1) | AU598543B2 (da) |
| CA (1) | CA1283358C (da) |
| DE (1) | DE3772521D1 (da) |
| DK (2) | DK179286D0 (da) |
| ES (1) | ES2007607A6 (da) |
| FI (1) | FI87529C (da) |
| IL (1) | IL82209A0 (da) |
| NO (1) | NO875299L (da) |
| WO (1) | WO1987006137A1 (da) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2062227T3 (es) * | 1989-08-21 | 1994-12-16 | Hoffmann La Roche | Composiciones farmaceuticas no parenterales para la insulina. |
| IL99699A (en) * | 1990-10-10 | 2002-04-21 | Autoimmune Inc | Drug with the option of oral, intra-intestinal, or inhaled dosing for suppression of autoimmune response associated with type I diabetes |
| FR2686899B1 (fr) | 1992-01-31 | 1995-09-01 | Rhone Poulenc Rorer Sa | Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant. |
| US6131567A (en) * | 1993-01-29 | 2000-10-17 | Aradigm Corporation | Method of use of monomeric insulin as a means for improving the reproducibility of inhaled insulin |
| EP1607086A1 (en) * | 1993-01-29 | 2005-12-21 | Aradigm Corporation | Method of use of monomeric insulin as a means for improving the reproducibility of inhaled insulin |
| TW404844B (en) | 1993-04-08 | 2000-09-11 | Oxford Biosciences Ltd | Needleless syringe |
| US6893664B1 (en) | 1996-06-17 | 2005-05-17 | Powderject Research Limited | Particle delivery techniques |
| US5948751A (en) * | 1996-06-20 | 1999-09-07 | Novo Nordisk A/S | X14-mannitol |
| UA65549C2 (uk) * | 1996-11-05 | 2004-04-15 | Елі Ліллі Енд Компані | Спосіб регулювання ожиріння шляхом периферійного введення аналогів та похідних glp-1 (варіанти) та фармацевтична композиція |
| SI0884053T1 (en) * | 1997-06-13 | 2003-02-28 | Eli Lilly And Company | Stable insulin formulations |
| ZA984697B (en) | 1997-06-13 | 1999-12-01 | Lilly Co Eli | Stable insulin formulations. |
| US20010053761A1 (en) * | 1998-01-08 | 2001-12-20 | Dimarchi Richard Dennis | Method for administering aspb28-human insulin |
| US6350458B1 (en) | 1998-02-10 | 2002-02-26 | Generex Pharmaceuticals Incorporated | Mixed micellar drug deliver system and method of preparation |
| US7070799B1 (en) * | 1998-02-10 | 2006-07-04 | Generex Pharmaceuticals, Inc. | Method for administering insulin to the buccal region |
| US6221378B1 (en) | 1998-02-10 | 2001-04-24 | Generex Pharmaceuticals Incorporated | Mixed micellar delivery system and method of preparation |
| US6849263B2 (en) * | 1998-12-21 | 2005-02-01 | Generex Pharmaceutical Incorporated | Pharmaceutical compositions for buccal delivery of pain relief medications |
| US6375975B1 (en) | 1998-12-21 | 2002-04-23 | Generex Pharmaceuticals Incorporated | Pharmaceutical compositions for buccal and pulmonary application |
| US7087215B2 (en) * | 1998-12-21 | 2006-08-08 | Generex Pharmaceuticals Incorporated | Methods of administering and enhancing absorption of pharmaceutical agents |
| US6451286B1 (en) | 1998-12-21 | 2002-09-17 | Generex Pharmaceuticals Incorporated | Pharmaceutical compositions for buccal and pulmonary administration comprising an alkali metal alkyl sulfate and at least three micelle-forming compounds |
| US6294153B1 (en) | 1998-12-21 | 2001-09-25 | Generex Pharmaceuticals, Inc. | Aerosol pharmaceutical formulation for pulmonary and nasal delivery |
| US6350432B1 (en) | 1999-03-19 | 2002-02-26 | Generex Pharmaceuticals Incorporated | Pressurized container having an aerosolized pharmaceutical composition |
| JP2003501404A (ja) | 1999-06-04 | 2003-01-14 | デルルックス ファーマシューティカル コーポレイション | 薬剤の脱水粒子からなる製剤およびこれの調製方法 |
| GB2355009A (en) * | 1999-07-30 | 2001-04-11 | Univ Glasgow | Peptides conjugated to bile acids/salts |
| AU2001266557A1 (en) | 2000-04-12 | 2001-10-23 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| US8061006B2 (en) * | 2001-07-26 | 2011-11-22 | Powderject Research Limited | Particle cassette, method and kit therefor |
| JP5424521B2 (ja) | 2001-12-21 | 2014-02-26 | ヒューマン ジノーム サイエンシーズ, インコーポレイテッド | アルブミン融合タンパク質 |
| CA2513213C (en) | 2003-01-22 | 2013-07-30 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| US8147426B2 (en) * | 2003-12-31 | 2012-04-03 | Nipro Diagnostics, Inc. | Integrated diagnostic test system |
| CA2652989A1 (en) * | 2006-06-08 | 2007-12-13 | Diabecore Medical Inc. | Derivatized insulin oligomers |
| ES2579229T3 (es) | 2007-03-13 | 2016-08-08 | Jds Therapeutics, Llc | Procedimientos y composiciones para la liberación sostenida de cromo |
| WO2008132224A2 (en) | 2007-04-30 | 2008-11-06 | Novo Nordisk A/S | Method for drying a protein composition, a dried protein composition and a pharmaceutical composition comprising the dried protein |
| WO2009002867A2 (en) | 2007-06-26 | 2008-12-31 | Nutrition 21, Inc. | Multiple unit dosage form having a therapeutic agents in combination with a nutritional supplement |
| EP2077132A1 (en) | 2008-01-02 | 2009-07-08 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dispensing device, storage device and method for dispensing a formulation |
| EP2662472B1 (de) | 2009-03-31 | 2019-02-27 | Boehringer Ingelheim International Gmbh | Verfahren zur Beschichtung einer Oberfläche eines Bauteils |
| US9265910B2 (en) | 2009-05-18 | 2016-02-23 | Boehringer Ingelheim International Gmbh | Adapter, inhalation device, and nebulizer |
| US10016568B2 (en) | 2009-11-25 | 2018-07-10 | Boehringer Ingelheim International Gmbh | Nebulizer |
| EP2504052B1 (en) | 2009-11-25 | 2022-07-27 | Boehringer Ingelheim International GmbH | Nebulizer |
| WO2011064163A1 (en) | 2009-11-25 | 2011-06-03 | Boehringer Ingelheim International Gmbh | Nebulizer |
| JP5874724B2 (ja) | 2010-06-24 | 2016-03-02 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ネブライザ |
| CN105749253A (zh) | 2011-03-01 | 2016-07-13 | Jds治疗有限公司 | 用于预防和治疗糖尿病、低血糖症及相关病症的胰岛素和铬组合物 |
| EP2694220B1 (de) | 2011-04-01 | 2020-05-06 | Boehringer Ingelheim International GmbH | Medizinisches gerät mit behälter |
| US9827384B2 (en) | 2011-05-23 | 2017-11-28 | Boehringer Ingelheim International Gmbh | Nebulizer |
| WO2013152894A1 (de) | 2012-04-13 | 2013-10-17 | Boehringer Ingelheim International Gmbh | Zerstäuber mit kodiermitteln |
| US9744313B2 (en) | 2013-08-09 | 2017-08-29 | Boehringer Ingelheim International Gmbh | Nebulizer |
| PL2835146T3 (pl) | 2013-08-09 | 2021-04-06 | Boehringer Ingelheim International Gmbh | Nebulizator |
| PL3139979T3 (pl) | 2014-05-07 | 2023-12-27 | Boehringer Ingelheim International Gmbh | Jednostka, nebulizator i sposób |
| EP3139984B1 (en) | 2014-05-07 | 2021-04-28 | Boehringer Ingelheim International GmbH | Nebulizer |
| TWI607770B (zh) | 2014-05-07 | 2017-12-11 | 百靈佳殷格翰國際股份有限公司 | 噴霧器及其容器 |
| US11865121B2 (en) | 2016-02-11 | 2024-01-09 | Nutrition21, LLC | Chromium containing compositions for improving health and fitness |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1381274A (en) * | 1971-01-28 | 1975-01-22 | Nat Res Dev | Insulin derivatives |
| IE36225B1 (en) * | 1971-01-28 | 1976-09-15 | Nat Res Dev | Improvements relating to insulin derivatives |
| GB1381273A (en) * | 1971-01-28 | 1975-01-22 | Nat Res Dev | Insulin derivatives |
| DK135268A (da) * | 1973-02-09 | |||
| US4153689A (en) * | 1975-06-13 | 1979-05-08 | Takeda Chemical Industries, Ltd. | Stable insulin preparation for nasal administration |
| US4164573A (en) * | 1975-06-13 | 1979-08-14 | Galinsky Alvin M | Composition and method for making a suppository for introducing a hypoglycemic agent into a mammal |
| GB1554157A (en) * | 1975-06-13 | 1979-10-17 | Takeda Chemical Industries Ltd | Stable insulin preparation for intra nasal administration |
| GB1527605A (en) * | 1975-08-20 | 1978-10-04 | Takeda Chemical Industries Ltd | Insulin preparation for intranasal administration |
| US4442090A (en) * | 1980-11-09 | 1984-04-10 | Kyoto Yakuhin Kogyo Kabushiki Kaisha | Absorption-promoting compounds, compositions thereof with pharmaceuticals and/or bases for rectal administration and method of use |
| DE3382112D1 (de) * | 1982-04-30 | 1991-02-21 | Ajinomoto Kk | Pharmazeutische zusammensetzung. |
| JPS58189118A (ja) * | 1982-04-30 | 1983-11-04 | Takeda Chem Ind Ltd | 経鼻投与製剤 |
| US4534894A (en) * | 1982-11-17 | 1985-08-13 | The Rockefeller University | Process for sulphation and phosphorylation of proteins and peptides |
| JPS59163313A (ja) * | 1983-03-09 | 1984-09-14 | Teijin Ltd | 経鼻投与用ペプチドホルモン類組成物 |
| IL68769A (en) * | 1983-05-23 | 1986-02-28 | Hadassah Med Org | Pharmaceutical compositions containing insulin for oral administration |
| US4746508A (en) * | 1983-06-06 | 1988-05-24 | Beth Israel Hospital Assn. | Drug administration |
| JPS60224616A (ja) * | 1984-04-24 | 1985-11-09 | Teijin Ltd | 経鼻投与用組成物 |
-
1986
- 1986-04-18 DK DK179286A patent/DK179286D0/da not_active Application Discontinuation
-
1987
- 1987-04-10 CA CA000534467A patent/CA1283358C/en not_active Expired - Lifetime
- 1987-04-13 IL IL82209A patent/IL82209A0/xx not_active IP Right Cessation
- 1987-04-14 JP JP62502696A patent/JPH01500116A/ja active Pending
- 1987-04-14 DE DE8787902450T patent/DE3772521D1/de not_active Expired - Lifetime
- 1987-04-14 EP EP87902450A patent/EP0267208B1/en not_active Expired - Lifetime
- 1987-04-14 AU AU73561/87A patent/AU598543B2/en not_active Ceased
- 1987-04-14 WO PCT/DK1987/000038 patent/WO1987006137A1/en not_active Ceased
- 1987-04-14 AT AT87902450T patent/ATE66614T1/de active
- 1987-04-14 US US07/132,969 patent/US5053389A/en not_active Expired - Fee Related
- 1987-04-15 ES ES8701124A patent/ES2007607A6/es not_active Expired
- 1987-12-08 DK DK642587A patent/DK160460C/da not_active IP Right Cessation
- 1987-12-16 FI FI875533A patent/FI87529C/fi not_active IP Right Cessation
- 1987-12-17 NO NO875299A patent/NO875299L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU598543B2 (en) | 1990-06-28 |
| FI87529C (fi) | 1993-01-25 |
| ES2007607A6 (es) | 1989-07-01 |
| US5053389A (en) | 1991-10-01 |
| DE3772521D1 (de) | 1991-10-02 |
| JPH01500116A (ja) | 1989-01-19 |
| DK642587D0 (da) | 1987-12-08 |
| FI875533L (fi) | 1987-12-16 |
| EP0267208A1 (en) | 1988-05-18 |
| IL82209A0 (en) | 1987-10-30 |
| ATE66614T1 (de) | 1991-09-15 |
| CA1283358C (en) | 1991-04-23 |
| DK642587A (da) | 1987-12-08 |
| DK160460C (da) | 1991-08-26 |
| AU7356187A (en) | 1987-11-09 |
| DK179286D0 (da) | 1986-04-18 |
| FI875533A0 (fi) | 1987-12-16 |
| EP0267208B1 (en) | 1991-08-28 |
| DK160460B (da) | 1991-03-18 |
| NO875299D0 (no) | 1987-12-17 |
| WO1987006137A1 (en) | 1987-10-22 |
| FI87529B (fi) | 1992-10-15 |
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